This third one is what I study. The “synaptic homeostasis hypothesis” is this idea that during the day, we make all these connections with the world around us. It used to be like, “Don’t go over there—the lions live there now.” Now it’s like, “What did Barbara say to me in the office?” These excitatory connections we make during the day result in the neurons in our brains getting overall higher activation. Then during the nighttime when we sleep, we have a downregulating process where the things that didn’t really matter to your survival sink to the bottom, and the things that are most relevant to your survival rise to the top. What deep sleep does is all the neural processing, and what REM sleep [rapid-eye-movement sleep] and light sleep do is basically integrate that into your long-term personality and understanding of the world.
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There are several different types of prescription sleeping pills, classified as sedative hypnotics. In general, these medications act by working on receptors in the brain to slow down the nervous system. Some medications are used more for inducing sleep, while others are used for staying asleep. Some last longer than others in your system (a longer half-life), and some have a higher risk of becoming habit forming.
Do not use in children under 12 years of age. Ask a doctor before use if you have: a breathing problem such as asthma, emphysema or chronic bronchitis; glaucoma; trouble urinating due to an enlarged prostate gland. Ask a doctor or pharmacist before use if you are taking any other drugs. When using this product: avoid alcoholic beverages; take only at bedtime. Stop use and ask a doctor if: sleeplessness persists continuously for more than two weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
How magnesium works: Magnesium plays a widespread role in the human body, helping regulate and many essential functions. One of magnesium’s most important roles is to enable healthy enzyme function. Magnesium is involved in more than 300 different enzyme-related reactions in the body’s cells. This mineral helps regulate blood pressure, cholesterol and blood sugar, and helps to control the body’s stress response. Getting sufficient magnesium helps the body maintain healthy levels of GABA, a neurotransmitter that promotes sleep, as well as elevating and stabilizing mood.
If your mind tends to race as soon as your head hits the pillow, put the brakes on this sleep-stealing habit by distracting yourself from rehashing the day’s events. One tip Breus offers his patients: Count down from 300 in multiples of three. “Because this task is mathematically complicated to do in your head,” he explains, “it forces your brain to focus on something else besides your worries.”
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What happens if you sleep with your eyes open? People sometimes sleep with their eyes open, which is known medically as nocturnal lagophthalmos. Symptoms caused by this condition include redness and blurry vision. Treatment options include eye drops, moisture goggles, or even surgery. It does not usually have serious complications. Learn more about it here. Read now
Clusters of sleep-promoting neurons in many parts of the brain become more active as we get ready for bed.  Nerve-signaling chemicals called neurotransmitters can “switch off” or dampen the activity of cells that signal arousal or relaxation.  GABA is associated with sleep, muscle relaxation, and sedation.  Norepinephrine and orexin (also called hypocretin) keep some parts of the brain active while we are awake.  Other neurotransmitters that shape sleep and wakefulness include acetylcholine, histamine, adrenaline, cortisol, and serotonin.
To start, we collected a list of 200 products widely available at drugstores and supplement shops, from Walgreens and CVS to Vitacost and Amazon. We limited the list to products marketed for adults and available without a prescription. We also made sure to include both natural and synthetic options — the common active ingredients in each work a little differently.
You’ve got an early day tomorrow, and you know you should be asleep — but instead you’re just lying there, wide awake, watching the minutes tick by on the clock. It’s called sleep-onset insomnia, and the irony is, the more you worry about falling asleep, the less likely you’ll be able to. But there are some easy things you can do to break the cycle. Below we discuss simple changes to your lifestyle and your sleep environment that can help you fall asleep faster and get a more restful night’s sleep.
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