Night shift workers often have trouble falling asleep when they go to bed, and also have trouble staying awake at work because their natural circadian rhythm and sleep-wake cycle is disrupted.  In the case of jet lag, circadian rhythms become out of sync with the time of day when people fly to a different time zone, creating a mismatch between their internal clock and the actual clock. 
Of all the sleep tips you could ever read or hear about, the most important one is to stick to one sleep schedule—every day. This means going to bed and waking up at the same time each day. When sleep has a regular rhythm, your biological clock will be in sync and all of your other bodily functions will go smoother, including your sleep. You are probably squirming as you read this tip, thinking about your own sleep issues and how you have anything but a regular sleep routine.
The hypothalamus, a peanut-sized structure deep inside the brain, contains groups of nerve cells that act as control centers affecting sleep and arousal.  Within the hypothalamus is the suprachiasmatic nucleus (SCN) – clusters of thousands of cells that receive information about light exposure directly from the eyes and control your behavioral rhythm.  Some people with damage to the SCN sleep erratically throughout the day because they are not able to match their circadian rhythms with the light-dark cycle.  Most blind people maintain some ability to sense light and are able to modify their sleep/wake cycle.
Tossing and turning all night never feels good—and most Americans are all too familiar with it. An estimated 164 million people struggle with sleep at least once a week, according to a 2016 survey from Consumer Reports. Insomnia can do worse than just tire you out the next day. If you're suffering from chronic lack of sleep, it can take a toll on your overall health.
Keep your room cool, clean, dark, and quiet. Do your best to keep the temperature in your bedroom just below 70 °F (21 °C). Sleeping in a hot and uncomfortable area is not a good or relaxing way to sleep, so do your best to get air regulation throughout the room. Clean up regularly, and change your sheets every 1 to 2 weeks, or whenever they’re dirty. A cluttered space can increase stress, and it can be tough to relax if your sheets are smelly.[14]

You've followed the usual tips for getting enough sleep — sleeping on a regular schedule, avoiding caffeine and daytime naps, exercising regularly, avoiding lighted screens before bed, and managing stress. Still, it's been weeks and a good night's sleep remains elusive. Is it time for an over-the-counter sleep aid? Here's what you need to know if you're considering medication to help you sleep.


In traditional Chinese medicine, insomnia often stems from kidney energy weakness. This syndrome is not necessarily related to kidney disease in Western medicine. A few signs of kidney energy weakness are a low backache, tiredness and fatigue, and a burst of energy at about 11 pm in the evening. Women in menopause often experience this type of insomnia. People who are taking anti-estrogenic drugs such as tamoxifen also experience this type of insomnia, however, they should not take herbal combinations such as the herbal formula liu wei di huang that may increase estrogen levels.
Routinely sleeping less than six or seven hours a night demolishes your immune system, more than doubling your risk of cancer. Insufficient sleep is a key lifestyle factor determining whether or not you will develop Alzheimer’s disease. Inadequate sleep—even moderate reductions for just one week—disrupts blood sugar levels so profoundly that you would be classified as pre-diabetic. Short sleeping increases the likelihood of your coronary arteries becoming blocked and brittle, setting you on a path toward cardiovascular disease, stroke, and congestive heart failure. Fitting Charlotte Brontë’s prophetic wisdom that “a ruffled mind makes a restless pillow,” sleep disruption further contributes to all major psychiatric conditions, including depression, anxiety, and suicidality.
How glycine works: Glycine is considered among the most important amino acids for the body. It exerts widespread influence over our bodies’ systems, structure, and general health, including cardiovascular, cognitive, and metabolic health. Glycine helps the body make serotonin, a hormone and neurotransmitter that has significant effects on sleep and mood.
The herb Vitex agnus castus (chaste tree) may help insomnia during menstrual periods or insomnia that is a side effect of premenstrual syndrome (PMS). In one study, women with moderate to severe premenstrual syndrome were treated with either a vitex agnus castus extract or a placebo for three menstrual cycles. Participants were asked to document their symptoms with a PMS diary with a daily rating scale of 17 symptoms. They reported fewer symptoms, especially less insomnia and negative affect, but their cramps didn't improve. However, chasteberry should not be used by anyone on birth control pills, hormone replacement therapy, or dopamine-related medications, according to the National Center for Complementary and Integrative Health.
The most important thing is taking that time off—it’s more conducive to your productivity. A lot of times people think they can like fight through and push harder and harder and harder to get better results, but sleep can give you that, too. When you transition in and out of sleep, your brain produces theta waves, which help you think more divergently. That’s why a lot of times when you wake up from a power nap or from sleeping, you’ll be able to solve that intractable problem that you couldn’t earlier in the day. That’s one of the reasons I think taking a break—whether it’s meditation or nap—during that circadian dip can be much more conducive to productivity.
A very helpful tool to track your sleep time and patterns is a sleep diary. Used in sleep research and clinical settings, a sleep diary is a handy reference to help people become familiar with their own natural patterns of sleep and wakefulness. The information that you will record in the sleep diary is simple and straightforward. It includes the time you go to bed, the time you wake up, your total hours of sleep, and whether you had any nighttime awakenings (and if so, how long you were awake) and any daytime naps. In addition, noting how you feel upon awakening (refreshed or tired), and how you feel at different times of the day will enable you to become more aware of your patterns, and help you determine if you are getting adequate sleep. Just keeping track of your sleep in this way may help improve your situation. If you need more help to improve your sleep, refer to Adopt Good Sleep Habits and Address Your Sleep Issues.
What you’re eating and drinking and when you’re enjoying it affects your sleep. Try to finish eating 2 to 3 hours before bedtime so your whole system is ready to relax. Drink alcohol in the early evening instead of right before bed so your body has time to digest it before you hit the sack. Make caffeine a morning-only drink and stick to other beverages in the afternoon and evening. Caffeine stays in your system longer than you might think and can disrupt your sleep.
She happens to be a licensed wellness practitioner who studies meditation, stress, and breathing techniques, and she told me it would change my life. You simply breathe in through your nose for four seconds, hold your breath for seven seconds, and exhale through your mouth for eight seconds. She explained that the studied combination of numbers has a chemical-like effect on our brains and would slow my heart rate and soothe me right to sleep that night. “It works,” she told me. “It’s crazy.”
The promise is in the name, and so far I haven’t been disappointed. I’ve tried every app like this one that I could find on the App Store, and this is by far “the best bank for its buck” I’m sure you could find one that has more features, but for a monthly subscription. It does what it promises and wakes me up when I’m already close to waking, and it’s gotten me to work on time every day that I’ve used it. I feel significantly better on mornings when I use Sleep Better than on mornings when I don’t. Great app. The only thing I wish they’d change is more comprehensive sleep statistics and information. I don’t know what some of their charts mean. For instance, how do they calculate my sleep efficiency? To me, 96% sleep efficiency should mean that I wake up feeling peppy and walking on sunshine. While I have woken up feeling much better most nights, there have been one or two mornings when I woke up feeling groggy because I’d only allowed myself five hours of sleep (not the app’s fault) and it still said I had 96-98% sleep efficiency. That doesn’t make sense to me unless they just mean out of the little sleep I happened to get that night. Overall, a great app, and I highly recommend it.
“This is a stimulus control theory,” says Meltzer. “Everything in life has a stimulus value, even your bed,” meaning your body should recognize that lying in bed means it’s time to go to sleep. To give your bed that value, the only things you should be doing in it are sleep and sex, she explains. “Getting out of bed if you can’t sleep is the hardest one to do, but it’s so important. If you’re spending 10 hours in bed, but only sleeping six, that’s really bad. Your bed becomes a place for thinking, worrying, watching TV, and not for sleeping.”
“By far the most common thing I recommend to patients is to take melatonin,” says Barone. The hormone, which is produced by the brain in preparation for sleep, is also available in pill and liquid form, which you can get at any health food store or pharmacy—good news because some modern behaviors can interfere with its natural production. “When we’re exposed to TVs, computers and phones with backlit displays, that tricks the brain into thinking it’s light out and it doesn’t make as much melatonin as it should.”
Melatonin supplements may improve sleep quality and morning alertness in older adults with insomnia. Timed-release melatonin is used to treat primary insomnia in people over age 55 in the European Union and elsewhere. In most studies on melatonin for insomnia in older adults, melatonin was taken up to two hours before bedtime for up to 13 weeks. The timing is important—when melatonin is taken in the morning, it delays circadian rhythms but advances them when taken in the afternoon or early evening.
The promise is in the name, and so far I haven’t been disappointed. I’ve tried every app like this one that I could find on the App Store, and this is by far “the best bank for its buck” I’m sure you could find one that has more features, but for a monthly subscription. It does what it promises and wakes me up when I’m already close to waking, and it’s gotten me to work on time every day that I’ve used it. I feel significantly better on mornings when I use Sleep Better than on mornings when I don’t. Great app. The only thing I wish they’d change is more comprehensive sleep statistics and information. I don’t know what some of their charts mean. For instance, how do they calculate my sleep efficiency? To me, 96% sleep efficiency should mean that I wake up feeling peppy and walking on sunshine. While I have woken up feeling much better most nights, there have been one or two mornings when I woke up feeling groggy because I’d only allowed myself five hours of sleep (not the app’s fault) and it still said I had 96-98% sleep efficiency. That doesn’t make sense to me unless they just mean out of the little sleep I happened to get that night. Overall, a great app, and I highly recommend it.
This secret was revealed in a 1981 book called "Relax and Win: Championship Performance," but has gained traction online in recent months. It's a meditation method designed specially for soldiers trying to fall asleep in difficult conditions. It's said to work for 96 percent of people after six weeks of practice. Here's how the Independent describes it:
These changes in the body's circadian rhythm coincide with a busy time in life. For most teens, the pressure to do well in school is more intense than when they were kids, and it's harder to get by without studying hard. And teens also have other time demands — everything from sports and other extracurricular activities to working a part-time job to save money for college.
Gallup has reported that over the past 50 years, we’re sleeping a whole hour less per night than we did in the 1950s. That’s a lot. A lot of that has to do with having TV on all the time, and mobile phones are taking it to the next level. But I think the biggest issue right now is the lack of work/life balance. I mean, I’m an entrepreneur, so I feel like I’m basically always “on”. A lot of people have jobs where they’re getting emails all hours the night, and there’s no longer a nine-to-five schedule.
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Create the right sleeping environment. Studies show that people sleep best in a dark room that is slightly on the cool side. Close your blinds or curtains (and make sure they're heavy enough to block out light) and turn down the thermostat (pile on extra blankets or wear PJs if you're cold). Lots of noise can be a sleep turnoff, too. Use a nature sounds or white-noise machine (or app!) if you need to block out a noisy environment.
Certain protein-rich foods like milk, eggs, peanuts, and soy contain an amino acid called tryptophan that causes sleepiness, says Alissa Rumsey, MS, RD, founder of Alissa Rumsey Nutrition and Wellness. For best results, combine these foods with a source of carbohydrates, which help more tryptophan enter the brain. Some recommendations: roasted soybeans, peanuts, sunflower seeds, cheddar cheese, canned tuna, and pistachios. You don't need much: "Even smaller snacks can provide a tryptophan dose that studies have shown to be significant in helping with sleep," Rumsey says.
Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.
The artificial (or “blue”) light emitted by screens can disrupt our bodies’ preparations for sleep by stimulating daytime hormones. Dubious bargain: trading sleep for Leno and Letterman. Basner M, Dinges DF. Sleep, 2009, Jul.;32(6):0161-8105. Reduce exposure by turning off TVs, phones, and computers at least one hour before bedtime. Can’t give up the Daily Show? At least dim a screen’s brightness, either manually or with the help of automated programs.
Melatonin. Melatonin is a naturally occurring hormone that increases at night. It is triggered by darkness and its levels remain elevated throughout the night until suppressed by the light of morning. Although melatonin does not appear to be particularly effective for treating most sleep disorders, it can help sleep problems caused by jet lag and shift work. Simple exposure to light at the right time, however, might be just as effective. If you take melatonin, be aware that it can interfere with certain blood pressure and diabetes medications. It’s best to stick with low doses—1 to 3 milligrams for most people—to minimize side effects and next-day drowsiness.
Melatonin has been used successfully for sleep enhancement in healthy individuals, as well as to reduce feelings of jet lag during global travels. This natural hormone is also being tested as a sleep aid with the elderly and other populations. In addition, studies are focusing on whether or not melatonin can help improve sleep patterns in individuals with depression.
Benzodiazepines are the oldest class of sleep medications still commonly in use. Benzodiazepines as a group are thought to have a higher risk of dependence than other insomnia sedative hypnotics and are classified as controlled substances. Primarily used to treat anxiety disorders, benzodiazepines that have been approved to treat insomnia include estazolam (brand name ProSom), flurazepam (Dalmane), quazepam (Doral), temazepam (Restoril), and triazolam (Halcion).

Clusters of sleep-promoting neurons in many parts of the brain become more active as we get ready for bed.  Nerve-signaling chemicals called neurotransmitters can “switch off” or dampen the activity of cells that signal arousal or relaxation.  GABA is associated with sleep, muscle relaxation, and sedation.  Norepinephrine and orexin (also called hypocretin) keep some parts of the brain active while we are awake.  Other neurotransmitters that shape sleep and wakefulness include acetylcholine, histamine, adrenaline, cortisol, and serotonin.
Sleeping with Fido isn’t so bad, according to a new Mayo Clinic study that found people who had a dog in the bedroom slept better than those who didn’t. But don’t let your pooch crawl under the covers: Participants who snuggled with their pets had poorer sleep quality than those who didn’t. If pet "co-sleeping" sounds like the insomnia cure for you, be sure your furry friend sleeps on the floor or in a pet bed of their own nearby so you both get an undisturbed, restful sleep. (Here are 5 ways to lose weight with your pet—so you can both live longer.)
Before recommending any action, your health care provider will explore with you a variety of possible causes for your sleep problems, including pain or depression. If necessary, he or she may recommend a sleep test (also known as a polysomnographic evaluation or sleep lab). Based on your symptoms, medical history and specific needs, your health care provider will be able to make a personalized treatment plan to help you achieve restful sleep.

The basal forebrain, near the front and bottom of the brain, also promotes sleep and wakefulness, while part of the midbrain acts as an arousal system.  Release of adenosine (a chemical by-product of cellular energy consumption) from cells in the basal forebrain and probably other regions supports your sleep drive.  Caffeine counteracts sleepiness by blocking the actions of adenosine.
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You know a good night’s sleep is the key to a happy and well-rested tomorrow. And getting enough shut-eye can help you drive more safely, maintain a healthy weight, and even lower your risk for heart disease and diabetes. But if you’re stuck in a cycle of tossing and turning—and then start stressing about the fact that you’re tossing and turning—it's all too easy to feel frustrated. Not so fast: With these tips you’ll be snoozing within minutes of your head hitting the pillow.
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