Hi Carol, Sorry to hear you are in such pain. Hopefully the results of the x-ray will show a way forward to solve the problem. You may benefit from physiotherapy to prevent frozen shoulder, or gentle chiropractic manipulation to correct misalignments of tiny joints – this certainly helped my other half who experienced a similar problem. A topical treatment containing capsaicin may help by damping down nerve generated pain. Magnetic therapy and using a heatlamp are other non-drug approaches which have been shown to improve circulation and boost healing of shoulder problems. Anti-inflammatories such as omega-3, turmeric or rosehip are other options. I hope you feel more comfortable soon. Best wishes, Sarah B

The main advantage of topical NSAIDs is the reduced exposure of the rest of the body to the product, which reduces the side effect profile. Given the toxicity of NSAIDs is related in part to the dose, it follows that topical treatments should have a better toxicity profile. Consequently, the cardiovascular risks of topical diclofenac, even in those with a high baseline risk of disease, should be negligible with the topical forms.

Despite what a majority of people may have been made to believe concerning the issue of anti-inflammatory creams and the pain-relieving creams the truth is that the two types of creams differ immensely. Pain relief creams serve the important function of disrupting the transmission of pain signals from different parts of the body to the brain thus allowing you to feeling a sense of temporary pain relief. However, most cream pain relievers would not have elements that would help reduce inflammation or swelling. Nevertheless, the anti-inflammatory creams and the pain relief creams both can be used for arthritis flare-ups and dealing with minor sports injuries. Nevertheless, for those people who may have never used these types of medications before or those who may not be sure of the type to use it is important to consult with the doctor before using such a product. Most all, never use the anti-inflammatory creams on a child or expectant mother unless who check in with your doctor.
When used together, menthol and methly salicylate create vasodilation (opening of the blood vessels) close to the surface of the skin.  Increased blood flow to the area of application is said to have pain-killing on the nerve receptors in the treated area.  When combined, these two ingredients also work together to form a class of treatment called counterirritants. Counterirritants work by tricking the body into feeling sensations other than pain. The menthol and methyl salicylate in muscle creams create conflicting feelings of warmth and cold. When the nervous system sends both of these sensations, at the same time, they compete with and ultimately block pain signals from travelling to the brain.  Together these ingredients, when delivered in muscle creams or sports balms, work to create a powerful 1-2 punch, killing pain and providing relief to aching muscles and joints.

Different creams and gels combine different pain-relieving ingredients for a greater, synergistic effect. The most effective natural ingredients are arnica, cannabidiol CBD oil, glucosamine, chondroitin, celadrin, comfrey root, capsicum, MSM and Green-lipped mussel extracts. The most effective pharmaceutical pain relief gel are those containing diclofenac, which is a stronger version of ibuprofen.
The US governmental agencies, through the FDA and others, routinely inspect the manufacture of vitamins or supplements made in this country, as they do for any other food product.[30,63,74] Contaminants, such as the recently discovered high lead content found in various Ayurvedic preparations that were made by an Indian manufacturer and imported into the US,[30,61,63,74,102] are generally thought to be uncommon, but can be a concern when purchasing imported supplements.
I use my Rogue Fitness Supernova ($40; roguefitness.com) for self-myofascial release (SMR). By applying pressure directly to sore muscles with my supernova, I am able to roll out knots (or adhesions) on the muscle. This allows the body to bring blood flow to troubled areas by transporting nutrients and oxygen to the muscles for faster repair." — Troy Brooks, YG Studios and founder TB Elite Fitness

"I love Elemental Herbs All Good Herbal Freeze with Arnica ($20; allgoodproducts.com) because the combination of menthol and arnica is incredibly cooling. Also, it's all-natural and super easy to just spray onto my sore areas. I also like Arnica Muscle and Joint Gel by Naturopathica ($28; naturopathica.com), which is a gel. You can rub it in and it really targets the sore muscles and joints." —Holly Rilinger, master Flywheel instructor, creator of LIFTED
Pain-relief gels and creams are available in the sizes and styles you need. We have roll ons for those spots that need concentrated effort. We have spray on pain-relief for those hard to reach spots. We even have individual packets for easy travel. Are you a coach or personal trainer with the need for large amounts of pain-relief? Save time and money by purchasing our bulk sizes. Pain relief gels are available in gallon sizes. Ointments are available in jars of up to five pounds each.
I am allergic to anti-inflammatory pills since they affect my stomach. I don't like the bad side effects they give either. So I look to topical anti-inflammatory cream to help when I have back, hip and/or shoulders sprains and strains. I have tried endless products: Penetrex, Aspercreme, Australian dream, Celadrin and so on. Out of these, Muscle Care works best for pain management. However, I do have some skin reactions to it so I have to give it a rest. When that happens, I use Topricin which works quite well. However, to me, SynthaFlex works as well, if not better. On top of that, it gives a strong cool menthol effect which Topricin doesn't. So when I overwork some muscles, I like to use SynthaFlex and/or Topricin. When my skin reactions calm down, I go back to using Muscle Care from time to time. I also use a roller to stretch which also helps. I hope this review gives others a better sense of what might work for them.
For example, water therapy is gentle on your body because the water supports the weight of your body and provides gentle resistance. The exercise is done in warm water, which is also soothing. There are many land-based exercise programs that can provide a gentle, endorphin-producing form of exercise, such as tai chi, or yoga programs designed for people with chronic pain conditions.
1., 2., and 3. Ginger, Turmeric, & Holy Basil – This set of herbs forms a sort of trinity in Ayurvedic medicine. All of them have anti-inflammatory properties. Turmeric (a curry ingredient) contains curcumins which ease inflammatory conditions like rheumatoid arthritis and psoriasis, according to the Methodist Research Institute in Indianapolis. “Each herb has its own scientific database of evidence,” says James Dillard, MD, author of The Chronic Pain Solution.

Ingredients:Active ingredients (in cream): Belladonna 3X, Capsicum 3X, Colocynthis 3X, Gnaphalium Polycephalum 3X, Hypericum Perforatum 3X, Magnesia Phosphorica 3X, Rhus Tox 3X. Inactive ingredients Water, Polyacrylamide, C13-14 Isoparaffin, Propylene Glycol, Methylparaben, Propylparaben, Capsicum Annuum Resin, Lavandula Angustifolia (Lavender) Oil, Salvia Officinalis (Sage) Leaf Oil, Laureth-7, Aloe Barbadensis Leaf Juice, Magnesium Ascorbyl Phosphate, Tocopheryl Acetate, Folic Acid, Retinyl Palmitate, Calendula Officinalis Flower Extract, Salvia Officinalis (Sage) Leaf Extract, Achillea Millefolium Extract, Sambucus Nigra Flower Extract, Foeniculum Vulgare (Fennel) Seed Extract, Citrus Aurantium Dulcis (Orange) Flower Extract, Rosa Canina Flower Extract, Ger anium Maculatum Extract.
Customers say that while they were skeptical at first, they are pleasantly surprised by just how well this lotion from Two Old Goats works to relieve arthritis pain. Its name come from its key ingredient—goat’s milk—which is blended with essential oils, including lavender, rosemary, peppermint, and eucalyptus in a formula designed to penetrate deep into your joints and muscles. All those oils also act as a moisturizer so it keeps your skin looking great too, and the pump bottle makes it easy to dispense.
Bromelian is a mix of proteolytic enzymes (those found in pineapples), which have been used for centuries to help indigestion and reduce inflammation. Studies indicate this product helps reduce pain associated with arthritis, especially when used in combination with some other natural pain-relieving agents making it a great natural remedy for inflammation and pain.
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Most of the active research with resveratrol has been done in neuro and cardioprotection, but several studies are being reported on resveratrol’s use for arthritic joint pain. Elmali et al, reported in 2007 using animals that intra-articular injection of resveratrol protects cartilage and reduces the inflammatory reaction in simulated knee osteoarthritis. The anti-inflammatory properties of resveratrol have also been observed in experimental animal models with paw edema, which is attributed to suppression of inflammatory prostaglandin synthesis.[29] Resveratrol is also a potent and specific inhibitor of TNF-α- and IL-1b-induced NF-kB activation. Resveratrol shows the anti-inflammatory properties as it suppresses COX-2 by blocking NF-kB activation.
“My husband and I prefer more natural, holistic pain relievers, and we were thrilled when we found Relief cream. We take it with us everywhere we go, use it religiously for joint pain, and recommend it to everyone we know. Relief is FAR superior to Biofreeze; there truly is NO comparison. Relief smells better, feels better, and just plain works better. Thank you so much for a natural alternative to pain medications that come with some really nasty 'side effects.'” *
“I cannot even tell you how AMAZING this stuff is. I never do reviews, but this product most certainly deserves one. I have dealt with MANY injuries, I was in a bad car wreck, and I have had more surgeries than I could count on both hands. My main area of pain is my upper back and neck. I have bulging disks, cervical stenosis, degenerative disk disease that causes horrible spasms, swelling, tension, and PAIN. I also have cancer and several other issues that put my pain level over the top every day. I have seen neurosurgeons, all of whom say they will eventually need to operate. I have done absolutely every possible treatment other than a spinal fusion, have had probably 10 injections, and they even went and tried to burn the nerve endings throughout my entire cervical spine, yet nothing worked. I can't even begin to tell you the medications the doctors have tried, each of which help some, but you get to a point where you don't want to constantly take medications forever. One day I was at my spine doctor's office and they had a bottle of Relief pain cream on the counter. While I was waiting there I asked the staff some questions about Relief and thought "yea, yea, but can I try it?" So, I put some on, and thought, "HOLY COW! What is this! Whatever this is, it's amazing!" Then and there I literally bought the rest of the supply they had on-hand because I couldn't believe how much it helped relieve my pains and aches. That night, I couldn't sleep because I was in so much pain, and none of my medications were helping. I felt like I was dying. So again, I put on some Relief cream and it helped soooo much. Since that day I never, ever, go anywhere without Relief! I will use this pain cream forever and continue to tell everyone I know about it because it truly works! I'm so glad I randomly tried this stuff at the doctor's office because I finally found something that gives true RELIEF!!” *
How much do you have to use at once and how often? Is it easy to apply too much? Generally, roll-on applicators are the best choice for reducing waste since it’s hard to put on too much when using them. It is also important to note that if you need deep muscle penetration roll-ons often don’t provide the same effect as hand rubbing gel or cream into the affected area. So be sure to keep that factor in mind as you review these products.
Vitamins are essential to health. Every natural thing that you eat contains the vitamins needed for growth, repair, bone density, pH balance and hormone regulation. The problem is that many people don’t have access to organic whole foods, so vitamin supplementation is important. When suffering from inflammation, pain and arthritis, the following vitamins may help.
Curcumin is a naturally occurring yellow pigment derived from turmeric (Curcuma longa), a flowering plant of the ginger family. It has traditionally been used as a coloring and flavoring spice in food products. Curcumin has long been used in both Ayurvedic and Chinese medicines as an anti-inflammatory agent, a treatment for digestive disorders, and to enhance wound healing. Several clinical trials have demonstrated curcumin’s antioxidant, anti-inflammatory, and antineoplastic effects. Results of a study by Zandi and Karin suggested that curcumin might be efficacious in the treatment of cystic fibrosis because of its anti-inflammatory effect.[121] Curcumin is known to inhibit inflammation by suppressing NF-kB, restricting various activators of NF-kB as well as stemming its expression.
When used together, menthol and methly salicylate create vasodilation (opening of the blood vessels) close to the surface of the skin.  Increased blood flow to the area of application is said to have pain-killing on the nerve receptors in the treated area.  When combined, these two ingredients also work together to form a class of treatment called counterirritants. Counterirritants work by tricking the body into feeling sensations other than pain. The menthol and methyl salicylate in muscle creams create conflicting feelings of warmth and cold. When the nervous system sends both of these sensations, at the same time, they compete with and ultimately block pain signals from travelling to the brain.  Together these ingredients, when delivered in muscle creams or sports balms, work to create a powerful 1-2 punch, killing pain and providing relief to aching muscles and joints.
The Biofreeze® pain relief gel is available in 16-, 32-, or 128-ounce bottles and is offered as the colorless or original green formula. The company has been making pain relief products for over 25 years. It is the #1 product that has been clinically used by professional healthcare hands-on providers, massage therapists, physical therapists, chiropractors, foot doctors (podiatrists), athletic coaches, instructors, and trainers. This is considered the best pain relief cream for muscle pain perfect for athletes. When professionals have over a hundred clients each week, the economical 128-ounce jug might be best for you for not running out. You always want it on hand for clients with sore aching body parts.
The use of fish oil (in the form of cod liver oil), an omega-3 EFA, for the treatment of muscular, skeletal, and discogenic diseases, can be traced back to the late 18th century as detailed by Curtis et al.,[24,25] Unfortunately, because of the rapid onset of rancidity of this polyunsaturated oil when exposed to air, and hence its disconcerting odor, cod liver oil fell out of favor. With improved extraction techniques, such as using a protective nitrogen blanket and enhanced oxygen-free encapsulation methods, there is less chance of oxidation during the manufacturing process. The therapeutic benefits of fish oil can now be realized without the regurgitation and odor of previous products caused by peroxides and rancid tasting fish oil.[14]
A study involving 172 people with osteoarthritis of the knee compared the use of a arnica gel with a prescribed, nonsteroidal anti-iflammatory gel (the NSAID piroxicam) with 1g of gel applied three times a day for 4 weeks. The results showed a pain reduction of 16.5 in the arnica gel group versus only 8.1 in the NSAID gel group and the researchers concluded that the Arnica gel was at least as effective and as well tolerated as the NSAID gel. A similar trial involving over 200 people with osteoarthritis of the hands showed that arnica gel was just as effective as an NSAID (ibuprofen) gel in reducing pain and improving hand function.

Ensure that the type of anti-inflammatory cream you buy for yourself, a friend, or family member is of the right quality and more efficient in helping you deal with your health predicaments. The best quality brands would be fast acting and gentle to your skin with every application. Most of all, the cream that you choose at any given point in time should not have any side effects otherwise you would be exposing yourself to the ordeal of tackling what would result from using the poor quality creams in hopes of dealing with a minor injury. The best cream would take the shortest period to help relieve you of any kind of pain or inflammation so that you would comfortably carry on with whatever you might be doing.


They are not also greasy and you can use apply it whenever you like. You can use it even when you are on a business meeting or you are on a party and no one will smell it due to its odorless feature. After using the pain relief products you feel relaxed within minutes and you feel healthy to work again. So don’t feel hesitate to have the best muscle pain relief cream nowadays and save a spot in your office or purse.
The Inactive ingredients are aloe barbadensis leaf extract, arnica Montana flower extract, Actium lappa root (burdock) extract, boswellia carterii resin extract, calendula officinalis extract, carbomer, camellia sinensis (green tea) leaf extract, camphor, glycerin, ilex paraguariensis leaf extract, isopropyl alcohol, isopropyl myristate, melissa officinalis (lemon balm) leaf extract, silica, tocopheryl (vitamin E) acetate, triethanolamine, water, blue 1, and yellow 5. Ilex is a skin protectant for topical skin barrier gels and lotions designed to protect the skin from harmful irritants such as urine and feces. It usually contains good things such as corn starch, white petroleum jelly, and zinc oxide.
Most of us spend a good part of our day sitting down, which may be more harmful than you realize. You can minimize the impact by maintaining good posture. Correct posture in a chair means having all the bones in your spine lined up neatly, like a stack of perfectly aligned blocks. You should keep your feet flat on the floor and your computer keyboard within easy reach so you’re not leaning forward or slumping. This is part of proper office ergonomics.
Most of us spend a good part of our day sitting down, which may be more harmful than you realize. You can minimize the impact by maintaining good posture. Correct posture in a chair means having all the bones in your spine lined up neatly, like a stack of perfectly aligned blocks. You should keep your feet flat on the floor and your computer keyboard within easy reach so you’re not leaning forward or slumping. This is part of proper office ergonomics.
The omega-3 fatty acids found in abundance in fish oil derived from cod, trout, herring, salmon and other coldwater fish are proven natural remedies to reduce inflammation. Research from Cardiff University in Great Britain found that cod liver oil not only relieves pain, but also stops and even reverses the damage caused by osteoarthritis and rheumatoid arthritis. Omega-3s help morning stiffness, regenerate joint tissue and have been shown to also aid in autoimmune disease like RA, lupus and psoriasis.
Pro Therapy Supplies now has aromatherapy items as well. These essential oils are 100 percent pure and natural. We carry the most popular and useful scents. These include Ylang Ylang, Peppermint, Lavender, Chamomile, Tea Tree and many more. Add these to our massage oils and creams or use them on their own. In addition to our single note essential oils, we stock blends that are made with your specific needs in mind. Some of our blends include calming, relaxation, serenity and vitality.
Rannou F, Pelletier JP, Martel-Pelletier J. Efficacy and safety of topical NSAIDs in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S18–21. PubMed #26806189. “Topical NSAIDs have a moderate effect on pain relief, with efficacy similar to that of oral NSAIDs, with the advantage of a better risk:benefit ratio. In real-life studies, topical and oral NSAIDs demonstrate an equivalent effect on knee pain over 1 year of treatment, with fewer adverse events due to lower systemic absorption of topical NSAIDs compared with oral NSAIDs.” BACK TO TEXT

When you think of a needle poking into your skin, the last thing you probably think about is natural pain relief. The truth is, though, that dry needling works by stimulating trigger points to reduce pain or disability. A 2007 study found dry needling significantly reduced shoulder pain by targeting a trigger point. Dry needling can also help deal with trigger points that reduce a person’s range of motion, which can lead to serious pain and musculoskeletal side effects.
Diclofenac is an extremely popular drug — again, we’re talking oral here — and it is associated with serious cardiovascular risks: “There is increasing regulatory concern about diclofenac. … Diclofenac has no advantage in terms of gastrointestinal safety and it has a clear cardiovascular disadvantage.”14 This has been in the news quite a bit, and NPR had a hit in 2013 with this headline: “World's Most Popular Painkiller Raises Heart Attack Risk.”
There is strong scientific support for the effectiveness of Alexander Technique lessons in the treatment of chronic back pain, according to a research review published in the International Journal of Clinical Practice in 2012. The review included one well-designed, well-conducted clinical trial demonstrating that Alexander Technique lessons led to significant long-term reductions in back pain and incapacity caused by chronic back pain. These results were broadly supported by a smaller, earlier clinical trial testing the use of Alexander Technique lessons in the treatment of chronic back pain.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
The first generic (cheaper) equivalent of Voltaren® Gel entered the marketplace in 2016, produced by Amneal Pharmaceutical. It should be widely available now. Both products are still prescription-only in the US, but fortunately they are over-the-counter almost everywhere else (there’s a rack of tubes of Voltaren by the till at my neighbhourhood drugstore).
Diclofenac topical gel (Voltaren) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the lining of the joints) in certain joints such as those of the knees, ankles, feet, elbows, wrists, and hands. Diclofenac topical liquid (Pennsaid) is used to relieve osteoarthritis pain in the knees. Diclofenac is in a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by stopping the body's production of a substance that causes pain.
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Physical therapists often recommend aquatic therapy — including exercises done in warm, therapeutic pools — for back pain. The buoyancy of the water helps alleviate strain on the joints to encourage strengthening and gentle stretching of the muscles. Even floating in warm water can help relax muscles and release tension as well as increase circulation, according to the Arthritis Foundation. With home whirlpool baths, try aiming the jets directly at your sore spots for a soothing underwater massage.
Dr. Pergolizzi venture offers this exquisite sore muscle cream that is scientifically proven to be about 2X effective over aches and arthritis dilemma than its competitors at a most fast pace. The foremost pain relief cream reviews primarily upheld it for the Oxygenated Oil and Menthol nurtured composition, which provides an enduring and cool comfort over all sorts of muscle pulls and swellings. The sore muscle cream owns a Zero Stinking texture and is also effective to eradicate the issue of vein throbbing. The pain relief cream reviews also favor it for its functionality to make stiffened muscles relax and treat even bursitis sting. The ‘Oxy Rub’ salve is available in both 2oz and 4oz tubes.
Rutin is a flavonoid composed of the flavonol quercetin and the disaccharide rutinose. Rutin is found naturally in a variety of plants, and dietary sources include black tea and apple peels. Rutin’s natural anti-inflammatory potential is attributed mainly to its powerful antioxidant activity. Rutin also helps maintain the levels of reduced glutathione, which is a powerful biological antioxidant. The combination of these activities helps to minimize the cellular damage and resulting inflammation caused by the various oxidative processes.
Resveratrol is a plant-based polyphenol molecule that is found in various concentrations of many different plant sources. The plant is called Japanese Knot weed or Polygonum cuspidatum, and the skins of red wine grapes are believe to have the most concentrated amounts of resveratrol. In plants, resveratrol is generally found in the plant skin and acts as a phytoalexin to protect the plant from infection, excessive UV radiation and aide in general plant defense. Resveratrol has also been found to have significant anti-mutation, anti-inflammatory, antoxidant and DNA protective actions, when consumed by animals and humans.
Customers say that while they were skeptical at first, they are pleasantly surprised by just how well this lotion from Two Old Goats works to relieve arthritis pain. Its name come from its key ingredient—goat’s milk—which is blended with essential oils, including lavender, rosemary, peppermint, and eucalyptus in a formula designed to penetrate deep into your joints and muscles. All those oils also act as a moisturizer so it keeps your skin looking great too, and the pump bottle makes it easy to dispense.
Cool it off. To do a 10-minute ice massage, fill up small paper or foam cups about one third full and freeze them. When ready to use, peel away the top of the cup to expose the ice and gently slide over the painful area. Try to avoid the bony parts of the joint, such as the knee cap and elbow points. Cover the affected area with a plastic wrap before applying the ice to protect the skin, and place a towel underneath to pick up the moisture as the ice melts. You can also use ice cubes wrapped in plastic for smaller areas. Cold packs and wraps applied for 15 to 30 minutes may also relieve sore lower back or shoulders.
Improve your posture. Good posture can prevent future arthritis pain. Years of compensating for a sore knee can result in pain in a hip or ankle. Jutting the abdomen forward can cause lower back pain, as can slouching in a desk chair. Consult a physical therapist. A physical therapist can observe how you sit, stand and walk and teach you how to adjust your posture so you can move with less pain.
Get enough restorative sleep. Getting enough sleep is critical to managing pain and promoting healing, so it's important to employ a variety of sleep aids to help you get a healthy amount of sleep. Regular exercise that physically exhausts the body helps promote deep sleep. Visualization, meditation, and other psychological techniques can also help you get to sleep and stay asleep.
All you need is to be ever-ready to dodge such life-halting aches with prompt effectiveness and regain your exuberance and potency. And to ensure that, having at your disposal an immaculate muscle rub ointment is an indispensable criterion. Pondering what are the grounds over which this ‘immaculacy’ gets established? Well, most fundamentally opt for such a muscle gel that is functional on a multi-dimensional spectrum.
"Dr. Teal's Epsom Salt ($5; target.com) is a must-have for my sore muscles. Aside from the fact that baths are relaxing and stress relievers, adding Epsom salt helps your body absorb and replenish magnesium levels that are depleted when you're stressed. Weekly Epsom salt baths are huge for my overall well-being!" —Anna Victoria, creator of the Fit Body Guides (Next, check out the sweat-proof makeup trainers can't live without.)
This Biofreeze brand gel comes in a small tube of 4 oz, perfect for bringing to work in a small purse or bag. The small tube contains a gel substance that provides a cooling effect to fight aching pain. The popular gel is an excellent choice for those with joint or muscle pain and is the perfect addition to a physiotherapists toolbox. It can be used topically on areas of the body and is easy to apply. It's also inexpensive compared to some other gel formulations on the market. The product has been around for 25 years and is not tested on animals.

Talking about your back pain with a therapist may bring some relief. In a UK study, back pain sufferers who had 90 minutes of group cognitive behavioral therapy a week for six weeks reported less pain during the treatment. (Cognitive behavioral therapy focuses on solving problems by changing thoughts and behavior.) A year later, 59% said their pain was totally cured, compared to just 31% in the group that did not go through therapy.
Prostaglandins act as short-lived localized hormones that can be released by any cell of the body during tissue, chemical, or traumatic injury, and can induce fever, inflammation, and pain, once they are present in the intercellular space. Thromboxanes, which are also hormone activators, can regulate blood vessel tone, platelet aggregation, and clot formation to increase the inflammatory response.[92,82] The inflammatory pathway is a complex biochemical pathway which, once stimulated by injury, leads to the production of these and other inflammatory mediators whose initial effect is pain and tissue destruction, followed by healing and recovery.[34,51] A major component of the inflammatory pathway is called the arachidonic acid pathway because arachidonic acid is immediately released from traumatized cellular membranes. Membrane-based arachidonic acid is transformed into prostaglandins and thromboxanes partly through the enzymatic action of cyclooxygenase (COX)[34,57]. There are two types of COX enzymes, COX-1 and COX-2. Both the enzymes act similarly, but selective inhibition (as accomplished by selective COX-2 inhibiting NSAIDs) can make a difference in terms of side effects.
For short-term pain relief, over-the-counter pain relievers including acetaminophen and NSAIDs (non-steroidal anti-inflammatory drugs) are sometimes suggested. The most common NSAIDs include aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve). Potential side effects of NSAIDs include stomach and liver problems. Talk to your doctor if you don't find relief after taking the recommended dose.
The processes used to prepare herb-derived compounds pose complications when it comes to determining the quantity and concentration of the products.[30,63,102] The preparation processes are not standardized, and therefore, the extraction process and the type of plant used may affect the true concentration of the product. In addition, there is a lack of uniformity within and between manufacturers. Although dietary supplements are not held to the same rigorous testing and standards as pharmaceutically derived medications in the US, there are many regulations that still control their manufacture because these are food products.
Hi Patricia, Sorry to hear about your experience. The patient information leaflet for diclofenac gel inside each pack advises that users should avoid applying on large areas of skin, that an amount ranging in size from a 1 penny to a 2 pence piece will usually be sufficient, and not to use it if you are already taking NSAID tablets. High blood pressure is not listed as a possible side effect, as this was not detected in clinical trials. As you say, diclofenac tablets and other oral NSAIDs are now associated with an increased risk of cardiovascular disease which is why the gel is considered a better option. I have coverd this in a post about ibuprofen increasing blood pressure here. Research looking into the long-term tolerability of topical diclogenac gel in people with an elevated risk of NSAID-related side effects, such as existing high blood pressure, type 2 diabetes, stroke and heart disease, suggests that the gel appears to be safe to use to treat osteoarthritis, even in these high risk groups. Having said that, everyone is different, due to the genes they have inherited, and you may have experienced an unusual, idiosyncratic reaction to the small amounts absorbed via the skin. It’s good that you or your doctor were monitoring your blood pressure to detect this. I have a website dedicated to lowering a high blood pressure, which includes lots of complementary approaches, that you may find helpful. Are you able to share the name of the herbal cream which you have found works better? Best wishes, Sarah B
One of the problems with pain relief creams is that application can become messy. It can be difficult to keep the cream contained to the area of skin that needs treating, and if you get the product on your hands, it’s easy to accidentally rub it into the eyes, which can be painful! To the rescue: Roll-on formulas, like Outback All-Natural Pain Relief, which allow for hands-free and targeted pain relief. The product contains just four ingredients: tea tree oil, vanilla, eucalyptus, and olive oil. The ingredients ease pain by reducing inflammation.
Arnica montana is a flowering mountain herb with a long history of traditional use in pain relief. Arnica extracts contain numerous pain reliefing ingredients, including sesquiterpene lactones, flavonoids which reduce inflammation, swelling and pain, plus thymol which fights infection. Arnica cream, gel and ointment is used to ease muscle pain and spasm, insect bites, superficial burns – including sunburn – sprains and painful joints caused by arthritis or other rheumatic disorders. Herbal arnica products contain measurable levels of active ingredients, while homeopathic arnica products contain lower levels that work in a different way. Research shows that arnica products are as effective at relieving painful joints as ibuprofen gel when applied two to four times a day.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: acetaminophen (Tylenol, in other products); angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (Prinivil, Zestril, in Prinzide and Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers such as candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); certain antibiotics, beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, Innopran); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); lithium (Lithobid); medications for seizures, and methotrexate (Otrexup, Rasuvo, Trexall). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
For natural headache relief, two essential oils team up for natural pain relief. Peppermint oil improves circulation and lavender reduces muscle tension — two ways to quickly stop a headache in its tracks. Try placing a few drops of peppermint or lavender oil into your hands and then rubbing the blend on your forehead, temples and back of neck. You can also dilute a few drops down by mixing the essential oils with almond, grapeseed or coconut oil.
The advantage of using a topical analgesic is that the medication works locally. Targeting pain more precisely using a medication applied to the skin can help skirt the side effects of oral drugs. This can be a boon for people whose stomachs are sensitive to NSAIDs. (Keep in mind that a small amount of the medicine still enters the bloodstream and ends up in the stomach and elsewhere, so a topical analgesic isn’t a guarantee against NSAID-related stomach irritation.)
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