NSAID medications have potential side effects, even though many of these medications can be obtained over-the-counter. Some of the side effects are minor, other certainly worrisome. Some people may be more prone to side effects given other medical conditions. For that reason, NSAID medication should be used with caution. If there is ever a question of whether or not it is safe for you to take these medications, and you should discuss this with your doctor. Anyone taking NSAID medications for more than a few days should have a discussion with her physician about the potential for side effects.
If you suffer from arthritis or other types of pain, you're probably all too familiar with drugs such as aspirin, Aleve, and Naproxen. All belong to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs), and all can be purchased without a prescription. But there is another related drug, available by prescription, you might want to talk with your doctor about: diclofenac, available as a gel, patch, or drop that you apply directly to your skin.
The advantage of using a topical analgesic is that the medication works locally. Targeting pain more precisely using a medication applied to the skin can help skirt the side effects of oral drugs. This can be a boon for people whose stomachs are sensitive to NSAIDs. (Keep in mind that a small amount of the medicine still enters the bloodstream and ends up in the stomach and elsewhere, so a topical analgesic isn’t a guarantee against NSAID-related stomach irritation.)
Research suggests that topical medications may be just as effective as oral ones. Many of them worked significantly better than placebo. These medications can come in the form of gels, creams, patches, and more. One study also saw decrease in pain when people applied lavender essential oil or ointments prepared with cayenne peppers with acupressure.
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in December 1998, celecoxib (Celebrex) was approved by the Food and Drug Administration (FDA) as the first selective COX-2 inhibitor for treatment of arthritis pain.[92,13,22] Rofecoxib (Vioxx) was approved several months later, followed by valdecoxib (Bextra).[92,28,67,79] These NSAIDs were designed to allow continued production of the gastrointestinally protective prostaglandins produced through the COX-1 enzyme system while blocking the COX-2 enzyme that produces the inflammatory prostaglandins.[34,45,51,89]
"Herbals or other nutraceuticals that may help in some way — as well as those which may not actually help — do almost universally have the potential to harm through unwanted side effects, allergic reactions, and undesirable interactions with other substances and medicines," says Sam Moon, MD, MPH, associate director of education at Duke Integrative Medicine, a division of Duke University Medical Center in Durham, N.C. "Relative safety must be very carefully balanced against likely effectiveness."
Talking about your back pain with a therapist may bring some relief. In a UK study, back pain sufferers who had 90 minutes of group cognitive behavioral therapy a week for six weeks reported less pain during the treatment. (Cognitive behavioral therapy focuses on solving problems by changing thoughts and behavior.) A year later, 59% said their pain was totally cured, compared to just 31% in the group that did not go through therapy.
Aspirin is now believed to target both the NF-kB and COX pathways. These agents inhibit the NF-kB pathway in endothelial cells and block NF-kB activation to inhibit leukocyte recruitment.[114,115,116] NSAIDs have also been found to inhibit both the COX system and the NF-kB pathway. Immunosuppressant drugs also reduce nuclear expression of NF-kB.[39,70,75] Research now indicates that blocking the activation of NF-kB along with other inflammation mediators [Table 2] is the major mechanism for reducing inflammation by natural compounds.

Research suggests that topical medications may be just as effective as oral ones. Many of them worked significantly better than placebo. These medications can come in the form of gels, creams, patches, and more. One study also saw decrease in pain when people applied lavender essential oil or ointments prepared with cayenne peppers with acupressure.
Did you know that the sensation of pain actually originates in your brain? Fortunately, we can actively alter the way our brain evaluates painful stimuli, helping to increase our pain tolerance and decrease painful symptoms.[12,13] Several techniques that aim to take more control over our minds and that relax the body can work wonders for pain control. Here are a few good examples:

Named for its hook-like horns, cat’s claw, a woody vine native to the Amazon rainforest and other places in South America, is known for containing an anti-inflammatory agent that aids in blocking the production of the hormone prostaglandin, which contributes to inflammation and pain within the body. Stick to the suggested doses to avoid diarrhea: 250 to 1,000 mg capsules one to three times daily.
I have nerve pain , spinal stenosis and no longer able to take oral medication that did help with symptoms but caused me to have allergic reactions .After stopping the oral medication I suffered with pain radiating from my lower back to my feet . At night I could not sleep. I am so glad that I found this miracle in a jar . I am sleeping very good at night without pain .It really do help with all my symptoms. I discussed the benefits of this with my doctor and have told family & friends .
This was a very informative post. I hate taking pills so anything thing that can help with any pain that I’m experiencing that you can just add topical is the best in my opinion. It’s great that it’s also as good as oral pain killers. And also has fewer side effects which is also another great thing. I’ll have to tell my friend about this because she has bad knee pain, so this would help her out a lot.
Side effects from topical medications include redness, itching, and other skin irritation. They are generally mild—and uncommon. The cause of skin irritation is often the material used to make the cream or gel, not the NSAID, says Dr. Joanne Borg-Stein, medical director of the Harvard-affiliated Spaulding-Wellesley Rehabilitation Center in Massachusetts. When that happens, it’s possible for a pharmacist to create a preparation with ingredients that are less irritating to your skin.
Customers attest to the fact that it relieves pain immediately, and say it’s a good staple to have in your medicine cabinet to treat all kinds of aches and pains beyond arthritis as well. They like that it’s not greasy, doesn’t burn and rubs in easily. Some say it works better than pills because you can apply it directly to the areas that are experiencing pain, and they love that it doesn’t have the medicinal smell of some other pain-relief creams.
Anti-inflammatory painkillers are a group of medicines that are used to ease muscle pains, sprains, strains and arthritis. They can be taken by mouth (tablets, capsules or liquids), injected, or applied to the skin. When they are applied to the skin they are called topical anti-inflammatory painkillers. Sometimes they are called 'topical non-steroidal anti-inflammatory drugs' (NSAIDs), or just 'topical anti-inflammatories'.

Side effects from topical medications include redness, itching, and other skin irritation. They are generally mild—and uncommon. The cause of skin irritation is often the material used to make the cream or gel, not the NSAID, says Dr. Joanne Borg-Stein, medical director of the Harvard-affiliated Spaulding-Wellesley Rehabilitation Center in Massachusetts. When that happens, it’s possible for a pharmacist to create a preparation with ingredients that are less irritating to your skin.
Cruciferous vegetables like broccoli, cauliflower, and cabbage have several health benefits. They naturally support detox organs like the liver and kidneys, and they contain plenty of natural fiber, folate, and vitamin C. But they can also help to regulate inflammatory bacteria within the digestive tract, especially H. pylori, which is implicated in ulcers and other chronic digestive conditions. (25) Since the body obtains all of its nutrients via digestion, an inflamed digestive system will contribute to inflammation throughout the rest of the body. Eating cruciferous vegetables daily can help to promote the healthy elimination of toxins as well as the proper regulation of the digestive system.

Chill it. Ice is best in the first 24 to 48 hours after an injury because it reduces inflammation, says E. Anne Reicherter, PhD, PT, DPT, associate professor of Physical Therapy at the University of Maryland School of Medicine. "Even though the warmth feels good because it helps cover up the pain and it does help relax the muscles, the heat actually inflames the inflammatory processes," she says. After 48 hours, you can switch to heat if you prefer. Whether you use heat or ice -- take it off after about 20 minutes to give your skin a rest. If pain persists, talk with a doctor.
Cetyl myristoleate (CMO) is a fatty acid, an ethylated esterified fatty acid derived from bovine tallow oil. Though it is similar to fish oil, it is made specifically to help joints through its action as a cellular lubricant. Clinical studies show CMO to be an effective natural anti inflammatory compound that promotes healthy joint function. It increases joint flexibility and range of motion by lubricating the joint at a cellular level. It works to decrease inflammation specifically in the joints and lubricate their movement. In other words, it increases the fluids that cushion the space between the joint bones. CMO is reported to effect change at the cellular level, within the cell membranes themselves. It assists in the reduction and prevention of breakdown in joint cartilage. This can be especially helpful for those suffering degenerative osteoarthritis. The Journal of Rheumatology reported on a double-blind study of patients with chronic knee osteoarthritis where the CMO group saw significant improvement while the placebo group saw none. In fact, the scientists were so impressed with the results they concluded CMO “may be an alternative to the use of non-steroidal anti-inflammatory drugs for treatment of osteoarthritis.”
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Snö presents this unique pain-killing ointment that is enhanced with the Swedish of ‘Fast Healing’ mechanism. Popular sore muscle relief reviews esteem the item for its compositional framework, which in turn is devised fundamentally by Arnica Montana and glycerin. The first one is famous as to pace up blood circulation while enacting over the ache with utmost promptness. Glycerin again keeps the body rightfully moisturized. The sore muscle relief reviews suggest using the salve to treat back, shoulder and neck pains and rejuvenate fatigued feet. It comes in a with airless propeller falcon and has a concentration of 2.75oz. The merchandise has a measure dynamics of 4 x 4 x 4 inches and is available in two functionality variants.
As a doctor I’ve tried, recommended and prescribed many pain-relieving creams and gels to treat painful joints, backache, sore muscles, strained tendons and sprained ligaments. Medical guidelines even recommend that doctors prescribe topical creams and gels to treat mild to moderate joint pain. The best pain relief creams and gels are often just as effective as oral painkillers, but with much less risk of side effects. When I experience muscle or joint pain, I prefer to use a pain relief cream myself.

For greater efficiency in using these types of products ensure that you by an anti-inflammatory cream that would not make you feel less comfortable when you are around other people. The best quality creams in such a case are the ones whose scent vanishes quickly with every application or the ones that would emit no scent thus allowing you to continue your daily life activities more proficiently with no distractions. The creams made of natural ingredients are the best quality you could ever buy because they are both efficient and would not leave you feeling less comfortable perhaps because of the irritating smell you may be forced to endure in the hopes of dealing with your pain or inflammation that may arise from an injury. Never spend your money on a product that would not serve your needs as desired because the very reason why we buy different products at different points in time is so that they could meet our needs if not then there would be no need of acquiring the product in the first place.

Topical glucosamine cream and gel can significantly reduce the pain of knee osteoarthritis within 4 weeks. One study involving a glucosamine cream found that 100% of those with arthritis of the shoulder gained benefit. Of those with arthritis of the ankle, wrist or elbow, glucosamine cream reduced pain in 75% of people, and it worked in 58% of those with knee osteoarthritis.


Homeopathic (diluted) herbal ointments featuring Arnica are claimed to be good medicine for muscle pain, joint pain, sports injuries and bruises, but their effectiveness is questionable. Known to most customers as an “herbal” arnica cream, most actually contain only trace amounts — too little to be a chemically active ingredient. Homeopathy involves extreme dilution of ingredients, to the point of completely removing them. Some other herbal ingredients may be less diluted and more useful. However, neither homeopathic or pure herbal creams of this type have produced results better than placebo in good quality modern tests. See Does Arnica Gel Work for Pain? A detailed review of popular homeopathic (diluted) herbal creams and gels like Traumeel, used for muscle pain, joint pain, sports injuries, bruising, and post-surgical inflammation. BACK TO TEXT

If you’re someone who experiences muscle and joint pain from time to time (or on a regular basis), you’ve probably tried quite a few options for pain relief. And you’re probably already using external pain relievers—the kind you apply directly to your skin for fast relief from sore muscles and joints. But have you thought of adding an external pain relief cream to the mix?
Within the cartilage around your joints is a chemical known as chondroitin. Chondroitin is naturally produced by the body. As you age, your natural supply starts to plummet. And a loss of chondroitin from cartilage is linked to a major cause of joint pain. Moreover, through wear and tear the joint cartilage breaks down, resulting in the condition of Osteoarthritis. We can’t regenerate cartilage on our own, but we can take a supplement called chondroitin sulfate which, studies show, can help slow down this degenerative process and help naturally reduce arthritic pain. Chondroitin sulfate is made from the cartilage of cows and other animals, and is often used in combination with other products including glucosamine and manganese.
Pain is a leading cause of insomnia—difficulty with falling asleep and/or staying asleep. Approximately two-thirds of people with chronic back pain suffer from some type of sleep disorder. Paradoxically, inadequate sleep can make your back pain worse. This vicious cycle makes it ineffective to treat just the pain. If you have sleep problems, you need to get the sleep problems addressed too.
Many pharmaceutical pain medications, while effective and useful at times, can be downright dangerous, but there is another solution to your pain problem. “Almost always, if we find pharmaceuticals doing the trick, we’ll find a plant doing the same trick—and doing it more safely,” remarks botanist James A. Duke, PhD, author of The Green Pharmacy Guide to Healing Foods.
Looking for a nonaddictive way to soothe aches? LifeSeasons’ award-winning Pain Bloc-R helps deliver the benefits of conventional approaches, including decreased aches and discomforts and increased relaxation, without the common pharmaceutical side effects. Pain Bloc-R combines natural ingredients and compounds, including Angelica dahurica, white willow bark, L-tetrahydropalmatine, and L-theanine, that work together to help support the body’s natural ability to relieve everyday aches.
Although it is normal to experience some pain and soreness when running or while engaging in similarly intense forms of physical activity, pain that persists long after you exercise is usually indicative of a greater problem. Be sure to consult with a medical professional before turning to any topical creams and gels; they can help you diagnose the source of your pain and may recommend alternate treatment options.

Zeng C, Wei J, Persson MS, et al. Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies. Br J Sports Med. 2018 Feb. PubMed #29436380. “Topical NSAIDs were effective and safe for OA. Diclofenac patches may be the most effective topical NSAID for pain relief. No serious gastrointestinal and renal AEs were observed in trials or the general population.” BACK TO TEXT


Those who have tried using this Neosporin product say that cuts and scrapes heal within three days when this ointment is applied and that pain subsides quickly. To properly use the ointment, be sure to first clean the affected area with mild soap or saline water. Apply the Neosporin and then use a bandage to properly protect the area while it heals.
How it works: A misaligned spine can cause muscle tension (read: pain). Both physical therapy and chiropractic treatment improve spinal alignment. Physical therapists strategically stretch and strengthen the muscles that help hold the spine in place. Chiropractors manipulate the spine to relieve areas of tension on the muscles. Consult your primary-care doctor for a referral.
Physical therapists use PEMF to heal fractures and torn cartilage faster, and surgeons recommend it as a post-op way to minimize soft tissue inflammation.[20][21] I use it to recover from workouts faster and keep inflammation low. PEMF machines send electromagnetic pulses through your tissue, gently stimulating anti-inflammatory and repair compounds.
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