“I would rate Corganics Relief pain cream as EXCELLENT! I have a diagnosis of Stage 4 lung cancer with metastases to bones, spine, brain and liver. Every morning and night I use it on my lower back and pelvis, calves and shins. I rely on the relief I get from Relief pain cream to be comfortable all day. Thank you for giving me the peace of mind with such a quality product. I appreciate your excellence!” *


The Penetrex® inflammation formulations have received rave reviews on Amazon.com® since 2009. With the Penetrex® Pain Relief Cream you will need fewer applications, and it actually heals and repairs your problem without masking the pain. You can get around expensive prescription medications using this product. You will have no side effects and it is not addictive. The cream will increase and enhance your range of motion and flexibility when you have no pain to deal with.

A study involving 172 people with osteoarthritis of the knee compared the use of a arnica gel with a prescribed, nonsteroidal anti-iflammatory gel (the NSAID piroxicam) with 1g of gel applied three times a day for 4 weeks. The results showed a pain reduction of 16.5 in the arnica gel group versus only 8.1 in the NSAID gel group and the researchers concluded that the Arnica gel was at least as effective and as well tolerated as the NSAID gel. A similar trial involving over 200 people with osteoarthritis of the hands showed that arnica gel was just as effective as an NSAID (ibuprofen) gel in reducing pain and improving hand function.

It’s estimated that up to 80 percent of adults experience persistent symptoms of lower back pain at some point in their lives, and about 31 million Americans struggle with the condition at any given time. Given its extremely high prevalence rate — whether due to a weak psoas muscle, sciatic nerve pain or some other cause — it’s not surprising that lower back pain is considered the single leading cause of disability worldwide according to the American Chiropractic Association, with half of all American workers reporting having occasional back troubles each year. (1) Naturally, this leads to millions searching for lower back pain relief.


Luminas fast pain relief patch is incredibly easy to use. You simply apply the patch on the troublesome area or a flat area of skin close to it if the pain is in a joint like the elbow or knee. That’s all you need to do to be on your way to being pain-free for up to 24-hours. You don’t need to worry about it coming off in the shower, bath, or pool either. You’re covered!

"I don't use topical pain relievers often, but when I do I use a product called Biofreeze ($15; performancehealth.com). It's a menthol-based gel that soothes local aches and pains in much the same way that ice therapy works but with less skin irritation, and the ability to be mobile once it's applied. It's also the product physical therapists and massage therapists choose." — Yusuf Jeffers, Tone House coach
3. Menthol, Eucalyptus and Mint Oils. Pain relieving creams containing either one or a combination of menthol, camphor, eucalyptus, spearmint, wintergreen or peppermint are thought to work by "confusing" nerve signals into feeling heat and cold sensations instead of pain.  Popular brands include Mentholatum Deep Heating Rub® and Icy Hot® (which may contain methyl salicylate too).  While many pain sufferers say these products work, its' relief is temporary at best.  These pain relief creams have to be reapplied frequently and tend to have strong fragrances.
The cream is affordable, effective, and gives wonderful results. You will want to use products that keep you that way. The hot cream is available in a large 8.8-ounce orange jar with either a silver metal or white plastic lid and the contents are always the same. It is 100% natural and 87% organic. It will firm up and tone your skin and remove that stubborn cellulite. Additionally, it warms up your aching and sore muscles for relief from that pain. Another benefit is that by firming up and reducing fat, you can be as trim as you want to be.
Cetyl myristoleate (CMO) is a fatty acid, an ethylated esterified fatty acid derived from bovine tallow oil. Though it is similar to fish oil, it is made specifically to help joints through its action as a cellular lubricant. Clinical studies show CMO to be an effective natural anti inflammatory compound that promotes healthy joint function. It increases joint flexibility and range of motion by lubricating the joint at a cellular level. It works to decrease inflammation specifically in the joints and lubricate their movement. In other words, it increases the fluids that cushion the space between the joint bones. CMO is reported to effect change at the cellular level, within the cell membranes themselves. It assists in the reduction and prevention of breakdown in joint cartilage. This can be especially helpful for those suffering degenerative osteoarthritis. The Journal of Rheumatology reported on a double-blind study of patients with chronic knee osteoarthritis where the CMO group saw significant improvement while the placebo group saw none. In fact, the scientists were so impressed with the results they concluded CMO “may be an alternative to the use of non-steroidal anti-inflammatory drugs for treatment of osteoarthritis.”
"I am a huge fan of Normatec recovery bags (starting at $1600; normatecrecovery.com) You put them on like sleeves and fill up with air while massaging the muscle. It is a game changer when it comes to helping with sore muscles. Not only does it help with soreness but helps flush lactic acids and improves circulation." —Chase Weber, celebrity personal trainer (Try his three-part total-body workout for strength, power, and stability.)
Many individuals perceive surgery as the best modality for their health issues and sometimes it is.  However, research has indicated that nerve damage unavoidably produced during a surgical operation will cause chronic pain in 15 – 50% of patients (3).  Other individuals are severely damaged by treatments such as chemotherapy and radiation that cause states of increased inflammation and pain.

Glutathione is a natural protein found within every cell in the body and consists of the amino acids Glutamic acid, L-cysteine, L-glycine. It is produced by the liver and is also found in fruit, vegetables and meats like mutton, lamb and beef. It is the most powerful antioxidant in the body and helps protect cells from free radical damage and oxidative stress, thereby improving cellular health and strengthening the immune system. As such, in addition to a host of other diseases, L-glutathione is useful in the natural treatment of rheumatoid arthritis.
Endorphins are hormones made naturally in your body. What most people don't know is that they can be just as strong as any manufactured pain medication. When endorphins are released in your body, they help block pain signals from registering with your brain. Endorphins also help alleviate anxiety, stress, and depression, which are all associated with chronic back pain and often make the pain worse.

As part of your exercise routine, you may want to consider doing yoga regularly for lower back pain relief. One study of over 960 people with low back pain found that those who completed a 12-week yoga program experienced greater improvements in back function and reduced pain compared to controls who did not participate. (4) There’s even evidence that mindfulness meditation, often practiced in some form with yoga, can also help people deal with chronic back pain more effectively. (5)
Ongoing pain can wreak havoc on your life, affecting your cherished relationships, finances, and your ability to get stuff done at work and at home. It can also interrupt your sleep and affect your mood. Because many other problems commonly occur along with chronic lower back pain, anything you can do for yourself that is a natural anti-depressant will help.
Topical treatments: One potential concern with dietary supplements is that some may interfere with medications you’ve been prescribed to treat back pain or other health conditions. For this reason, Grossman suggests topical treatments: “Gels and creams can be very helpful and won't interfere with supplements or medications,” she explains. “They're generally inexpensive, too.”

I recommend a woman takes 1,500 milligrams starting on the first day of her period and continuing until ovulation. If your’e on certain antidepressants, you have a bleeding or a seizure disorder, you’re on phenothiazine drugs for schizophrenia, or you’re being treated for high blood pressure, you should talk to your doctor before starting evening primrose oil.
All the aforementioned creams are exceptional in dealing with joint pains. Therefore, if you wish to deal with pain experienced on the back, knees, and elbow then any of the creams outlined above would do you some good. Even if you may not be a fun of using pain relief medications the ten distinctive anti-inflammatory creams that have been discussed earlier would make you develop a liking for these types of medication.
Injections. If other measures don't relieve your pain, and if your pain radiates down your leg, your doctor may inject cortisone — an anti-inflammatory medication — or numbing medication into the space around your spinal cord (epidural space). A cortisone injection helps decrease inflammation around the nerve roots, but the pain relief usually lasts less than a few months.
The Inactive ingredients are aloe barbadensis leaf extract, arnica Montana flower extract, Actium lappa root (burdock) extract, boswellia carterii resin extract, calendula officinalis extract, carbomer, camellia sinensis (green tea) leaf extract, camphor, glycerin, ilex paraguariensis leaf extract, isopropyl alcohol, isopropyl myristate, melissa officinalis (lemon balm) leaf extract, silica, tocopheryl (vitamin E) acetate, triethanolamine, water, blue 1, and yellow 5. Ilex is a skin protectant for topical skin barrier gels and lotions designed to protect the skin from harmful irritants such as urine and feces. It usually contains good things such as corn starch, white petroleum jelly, and zinc oxide.

People who use nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as topical diclofenac (Pennsaid, Voltaren) may have a higher risk of having a heart attack or a stroke than people who do not use these medications. These events may happen without warning and may cause death. This risk may be higher for people who use NSAIDs for a long time. Do not use an NSAID such as topical diclofenac if you have recently had a heart attack, unless directed to do so by your doctor.Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke; if you smoke; and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of your body, or slurred speech.
Funny how things like this slip through the cracks. I communicate with patients and professionals locally and abroad more or less all day every day, study and research musculoskeletal pain problems obsessively, and am more or less constantly immersed in answering the question, “What can you do for body parts that hurt?” And yet I didn’t hear about this stuff for a good year after it had already hit the shelves.
Just how does acupuncture work? According to traditional Chinese medicine, pain results from blocked energy along the meridians of the body, which are unblocked when acupuncture needles are inserted along these invisible pathways. Acupuncture may also release natural pain-relieving opioids, send signals to the sympathetic nervous system, and release neurochemicals and hormones.
Various studies have also shown that NSAIDs can delay muscle regeneration and may reduce ligament, tendon, and cartilage healing.[4,13,77] Specifically, NSAIDs are believed to wipe out the entire inflammatory mediated proliferative phase of healing associated with WBC actions (days 0–4). A study of the effects of NSAIDs on acute hamstring injuries was done in humans by Reynolds et al.,[93] and these investigators concluded that patients who used NSAIDs did not experience a greater reduction of pain and soft-tissue swelling when compared with the placebo group. Interestingly enough, the authors noted that the NSAIDs’ group had worse pain associated with severe injuries compared with the placebo group.
Many patients have told me they find celadrin cream effective for rapid relief of painful joints. It appears to work best when you apply it all around the joint – for example in a continuous band around the front, sides and back of a knee. One patient, who had two arthritic knees, told me he performed a personal experiment in which he applied celadrin cream around one knee but not the other. He was amazed at the difference in the treated knee which, within hours, became less painful and more mobile. Needless to say, he soon started applying it to both knees!
"I have used your Arthritis Pain Relief Cream for a couple of years now, and I don’t know how I could do without it. I have arthritis in my back, arms, legs, and fingers. When I’m hurting, I apply the Cream, and the pain is gone in just a few minutes. I have referred this product to several friends and relatives. I also like your Intensive Night Repair Cream. I can’t live without it."
Chondroitin sulphate chains bind to hyaluronic acid to form ‘springy’ molecules that increase the strength and elasticity of cartilage, making it more resilient. Chondroitin also acts as a signal to inhibit the enzymes responsible for breaking down cartilage, and to increase the production of collagen. Chondroitin is therefore an ideal complement to glucosamine and the two are often combined in joint and muscle pain relief creams.
Ginger is in the same family of anti-inflammatory spices as turmeric. While they share similar benefits, ginger is well known for its ability to relieve nausea associated with pregnancy and cancer treatments. It can also relieve pain in the same category as NSAIDs, making it another effective alternative to over-the-counter medications that have unpleasant side effects. (18)

Schematic showing that when a cell membrane is injured the arachidonic acid pathway is activated to initiate the local inflammatory response through the production of prostaglandins, thromboxanes, and leukotrienes. Their activation requires the enzymes COX and LOX. The NSAIDs can block COX action and thereby prevent the formation of the COX-derived inflammatory mediators. 5-HPETE = 5-hydroperoxyeicosatetraenoic acid; LTC4 = leukotriene C4; PGE2 = prostaglandin E2; PGF2 = prostaglandin F2; PGI2 = prostacyclin; TXA2 = thromboxane.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with topical diclofenac 1% and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) to obtain the Medication Guide.

The InstaNatural™ pain relief gel is ohhh soo cooling for your sore aching back, chest, neck, elbows, arm muscles, knees, and arthritic conditions. Arthritis makes your bones ache and skin tender at that area. This will relax you and make you feel more comfortable. Arthritis stiffness is indeed very painful, especially in the fingers. This might provide relief to rheumatoid arthritis sufferers too, a more significant and painful condition. It performs well for tendonitis, carpal tunnel syndrome, sciatica, tennis elbow, golfer’s elbow, plantar fasciitis, fibromyalgia, and more aches and pains. The 2-ounce jar of gel will not stain your skin or clothes.
A warming cream from Sombra with a pleasant orange scent. Good for the relief of pain related to inflammation. It doesn't contain any artificial fragrances or dyes. Also suitable for muscle pain and aches. Sombra also sells a cooling gel and different packaging formats for various uses. The gel is also free of animal ingredients so vegans can happily use it when they experience joint or muscle pain. This gel uses a warming sensation to help alleviate pain and inflammation. Users should take care to wash their hands after application to avoid getting it in their eyes or around the eye area.
The exhibited pain cream of Penetrex brand comprises an evolved pain-relieving mechanism, which in effect is crafted by availing the highly effective ingredients of Cetyl Myristoleate or CMO and Methylsulfonylmethane or MSM. Whereas the first one enacts over the ground cause of all muscular and joint aches that is inflammation, the second one works over the physiological cells and fortifies them to fight pains. Other serviceable ingredients in the formulary include Arnica, Vitamin B6 and Choline. The pain cream is non-sticky and stain-free and vowed to gratis steroids and drugs. It is especially famous for dodging aches over knee, arm, calf, hip and wrist. The parent brand vends it in a 2oz volume pot.

In contrast, the guidelines of the American Pain Society and American College of Rheumatology have in the past recommended topical methyl salicylate and topical capsaicin, but not topical NSAIDs. This reflects the fact that the American guidelines were written several years before the first topical NSAID was approved for use in the United States. Neither salicylates nor capsaicin have shown significant efficacy in the treatment of OA.


In addition to the other methods and strategies discussed throughout my book, I recommend taking natural remedies that reduce pain and inflammation, protect joint health and promote healing without side effects. Below I offer an overview of 20 different supplements formulas or ingredients often found within such formulations. Read each, keeping in mind your specific condition and how some may be more effective for you than others.

There's a reason there are so many roll-ons on this list. They're super handy and easy to use. This CobraZol gel provides quick relief that lasts up to 10 hours. It's a good choice for both chronic and acute pain. This gel comes in a 2 oz format. Believe it or not, this stuff actually contains cobra venom. Venom apparently is thought to help de-active pain pathways and reduce pain. This roll-on is a great way to manage pain and help users wean off of more serious and potentially dangerous pain medications.


Wasabi is another spicy food with natural painkilling properties. Scientists are studying the isothiocyanates in wasabi as potential pain relievers. Researcher from University of California San Francisco made a recent discovery suggesting that isothiocyanates could block an inflammation receptor, making it a potentially important natural painkiller. (2)
As I write in this month’s Harvard Men’s Health Watch, these so-called topical analgesics work best for more superficial joints like the knees, ankles, feet, elbows, and hands. “In those areas, the medication can penetrate closer to the joint,” says Dr. Rosalyn Nguyen, a clinical instructor in physical medicine and rehabilitation at Harvard Medical School.

Burdock root is a natural botanical for that is in wide use for many conditions, among them arthritic pain, swollen joints and rheumatism. More than anything else, clinical studies have found it most effective as a blood purifier that helps to rid the body of deleterious toxins and clear congestion from the circulatory, lymphatic, respiratory and urinary systems. Burdock is said to cleanse and eliminate long-term impurities from the blood very rapidly through its action on both the liver and kidneys. For those who suffer from arthritis and have taken too much Tylenol, burdock root has been clinical proven to protect the liver cells from the damage of taking acetaminophen. It is believed to stimulate the gallbladder and encourage liver cells to regenerate.
People who use nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as topical diclofenac (Pennsaid, Voltaren) may have a higher risk of having a heart attack or a stroke than people who do not use these medications. These events may happen without warning and may cause death. This risk may be higher for people who use NSAIDs for a long time. Do not use an NSAID such as topical diclofenac if you have recently had a heart attack, unless directed to do so by your doctor.Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke; if you smoke; and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of your body, or slurred speech.

Try taking one 250-milligram capsule of valerian four times a day. Some scientists claim that this herb’s active ingredient interacts with receptors in the brain to cause a sedating effect. Although sedatives are not generally recommended, valerian is much milder than any pharmaceutical product. (Valerian can also be made into a tea, but the smell is so strong-resembling overused gym socks-that capsules are vastly preferable.)

"Dr. Teal's Epsom Salt ($5; target.com) is a must-have for my sore muscles. Aside from the fact that baths are relaxing and stress relievers, adding Epsom salt helps your body absorb and replenish magnesium levels that are depleted when you're stressed. Weekly Epsom salt baths are huge for my overall well-being!" —Anna Victoria, creator of the Fit Body Guides (Next, check out the sweat-proof makeup trainers can't live without.)
These proinflammatory cytokines result in chemoattractant for neutrophils and help them to stick to the endothelial cells for migration. They also stimulate white cell phagocytosis and the production of inflammatory lipid prostaglandin E2 (PGE2). NSAIDs’ ability to interfere with the production of prostaglandin during the inflammatory cascade is the major mechanism cited for the anti-inflammatory success of these medications [Figure 1].[112]
Warming tissues eases arthritis pain by increasing blood flow to affected areas, which decreases inflammation, relaxes tight muscles, and eliminates waste products, like lactic acid, that cause stiffness and soreness. Cold decreases blood flow to reduce swelling, slows the transmission of pain signals through nerves, and inhibits inflammatory chemicals. Cold therapy is best for pain and swelling after exercise, during a flare, or in the first 48 to 72 hours after an injury. Here are some ways to soothe joint pain with heat and cold at home:

Beauty Breeze brings this exquisite muscle cream that emerges as a distinctive one for the factuality of getting crafted from peerless pain-soothing herbs and functional emollients extracted from Cajput, Clove, Mint and Cassia. Enriched by the nimbleness of Thai masseurs, this ‘Tiger Balm’ class cream for sore muscles is also lab-tested to be effective over severe type migraines. The reddish consistency muscle cream is accredited as an ‘Extra Strength’ one and is especially operative over abdominal cramps, spinal ache and joint inflammation. Vended in a unique edged carton-pattern container, the cream for sore muscles has a 30 gram density. It has a measure dynamics of 3 x 3 x 4.1 inches and a menthol aroma.

Rannou F, Pelletier JP, Martel-Pelletier J. Efficacy and safety of topical NSAIDs in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S18–21. PubMed #26806189. “Topical NSAIDs have a moderate effect on pain relief, with efficacy similar to that of oral NSAIDs, with the advantage of a better risk:benefit ratio. In real-life studies, topical and oral NSAIDs demonstrate an equivalent effect on knee pain over 1 year of treatment, with fewer adverse events due to lower systemic absorption of topical NSAIDs compared with oral NSAIDs.” BACK TO TEXT
The advantage of using a topical analgesic is that the medication works locally. Targeting pain more precisely using a medication applied to the skin can help skirt the side effects of oral drugs. This can be a boon for people whose stomachs are sensitive to NSAIDs. (Keep in mind that a small amount of the medicine still enters the bloodstream and ends up in the stomach and elsewhere, so a topical analgesic isn’t a guarantee against NSAID-related stomach irritation.)

Try taking one 250-milligram capsule of valerian four times a day. Some scientists claim that this herb’s active ingredient interacts with receptors in the brain to cause a sedating effect. Although sedatives are not generally recommended, valerian is much milder than any pharmaceutical product. (Valerian can also be made into a tea, but the smell is so strong-resembling overused gym socks-that capsules are vastly preferable.)
When you think of a needle poking into your skin, the last thing you probably think about is natural pain relief. The truth is, though, that dry needling works by stimulating trigger points to reduce pain or disability. A 2007 study found dry needling significantly reduced shoulder pain by targeting a trigger point. Dry needling can also help deal with trigger points that reduce a person’s range of motion, which can lead to serious pain and musculoskeletal side effects.
Improve your posture. Good posture can prevent future arthritis pain. Years of compensating for a sore knee can result in pain in a hip or ankle. Jutting the abdomen forward can cause lower back pain, as can slouching in a desk chair. Consult a physical therapist. A physical therapist can observe how you sit, stand and walk and teach you how to adjust your posture so you can move with less pain.
NSAID medications have potential side effects, even though many of these medications can be obtained over-the-counter. Some of the side effects are minor, other certainly worrisome. Some people may be more prone to side effects given other medical conditions. For that reason, NSAID medication should be used with caution. If there is ever a question of whether or not it is safe for you to take these medications, and you should discuss this with your doctor. Anyone taking NSAID medications for more than a few days should have a discussion with her physician about the potential for side effects.
Pycnogenol inhibits TNF-α–induced NF-kB activation as well as adhesion molecule expression in the endothelium. Grimm et al, recently reported that oral intake of pycnogenol inhibited NF-kB activation in lipopolysaccharide-stimulated monocytes as well, thus decreasing the inflammatory response. It also statistically significantly inhibited matrix metalloproteinase-9.[46] This matrix-degrading enzyme is highly expressed at sites of inflammation, and contributes to the pathogenesis of various chronic inflammatory diseases.[96]
Also referred to as "hypnosis," hypnotherapy is a mind-body technique that involves entering a trance-like state of deep relaxation and concentration. When undergoing hypnotherapy, patients are thought to be more open to suggestion. As such, hypnotherapy is often used to effect change in behaviors thought to contribute to health problems (including chronic pain).
I use my Rogue Fitness Supernova ($40; roguefitness.com) for self-myofascial release (SMR). By applying pressure directly to sore muscles with my supernova, I am able to roll out knots (or adhesions) on the muscle. This allows the body to bring blood flow to troubled areas by transporting nutrients and oxygen to the muscles for faster repair." — Troy Brooks, YG Studios and founder TB Elite Fitness
You may already have tried exercise and over-the-counter (OTC) pain relievers you take by mouth. These include nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen. Another option is to try one of the many OTC topical creams that can help relieve arthritis pain. Here’s the low-down on these products to help you decide which arthritis cream might be best for you.
Massage. Various forms of body work can provide temporary pain relief. You can try full-body Swedish massage for  stress relief and relaxation; deep-tissue massage, which uses pressure and slow strokes on deeper muscle tissue to release knots and relieve tension; or myofascial release, which uses long, stretching strokes to relieve tension around the connective tissue of the muscles.
Physical therapists use PEMF to heal fractures and torn cartilage faster, and surgeons recommend it as a post-op way to minimize soft tissue inflammation.[20][21] I use it to recover from workouts faster and keep inflammation low. PEMF machines send electromagnetic pulses through your tissue, gently stimulating anti-inflammatory and repair compounds.
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