Traditional wisdom says that NSAID pain relievers only damage your gut lining if you take them every day for a long time, but recent research disagrees. High-level athletes with stress-related intestinal damage tried taking ibuprofen to improve muscle soreness and recovery. Ibuprofen ended up damaging their gut lining even further after just a couple weeks; it increased inflammation and made their original pain issues worse.[3] In fact, a single dose of aspirin can significantly increase your intestinal permeability.[4]

Sudden and intense cold exposure makes you release cold-shock proteins, a special class of proteins that decrease inflammation and speed up recovery.[10] To get the benefits of cold therapy, you can take an ice bath or use a cryotherapy chamber, like the one at Bulletproof Labs. Cryotherapy’s benefits go far beyond inflammation, too. Get a full breakdown of how cryotherapy upgrades your biology.
The power of Luminas pain patches on pain and inflammation has successfully been measured with the help of thermography technology. When inflammation occurs, blood flow is increased in that area, causing the temperatures to rise. This is identifiable on our infrared cameras. Once a Luminas pain patch is applied to the area, you can see it working right away. In as little as 15 minutes, most of the inflammation and pain had disappeared.
This cream acts as a natural pain reliever with every application on the body. With this particular cream, you are assured of getting relieved from the pain that you may experience on the joints and muscles, back pain, and arthritis pain. It would also assist you in effectively dealing with bruises by helping you deal with pain while reserving the gentle touch.

I’ve just emphasized that Voltaren is mainly appropriate for shallow inflammation, but there is some evidence that Voltaren might be able to “reach deeper.” This is hardly the stuff of medical certainty yet, but researchers Huang et al found that Voltaren treated pain coming from deep inside the spine, right in the centre.6 They concluded that it could be a “convenient and safe clinical intervention” for a few types of back pain. An anti-inflammatory gel will likely fail with many kinds of back pain, but there’s also virtually no down-side to trying. See my low back pain tutorial for extremely detailed information about medications for back pain.
Diclofenac is an extremely popular drug — again, we’re talking oral here — and it is associated with serious cardiovascular risks: “There is increasing regulatory concern about diclofenac. … Diclofenac has no advantage in terms of gastrointestinal safety and it has a clear cardiovascular disadvantage.”14 This has been in the news quite a bit, and NPR had a hit in 2013 with this headline: “World's Most Popular Painkiller Raises Heart Attack Risk.”
Topical treatments: One potential concern with dietary supplements is that some may interfere with medications you’ve been prescribed to treat back pain or other health conditions. For this reason, Grossman suggests topical treatments: “Gels and creams can be very helpful and won't interfere with supplements or medications,” she explains. “They're generally inexpensive, too.”
One reviewer describes the Penetrex cream as “magic in a jar,” saying that it helps her cope with back discomfort that doesn’t respond to other pain-treatment methods, whether massage or physical therapy. People say that the Penetrex cream has helped them while recovering from injury or surgery, but many also use it on a daily basis to alleviate arthritis pain as well as the normal but nagging aches that can spring up later in life.
"I don't use topical pain relievers often, but when I do I use a product called Biofreeze ($15; performancehealth.com). It's a menthol-based gel that soothes local aches and pains in much the same way that ice therapy works but with less skin irritation, and the ability to be mobile once it's applied. It's also the product physical therapists and massage therapists choose." — Yusuf Jeffers, Tone House coach
An ancient mind-body practice, meditation has been found to increase pain tolerance and promote management of chronic pain in a number of small studies. In addition, a number of preliminary studies have focused specifically on the use of meditation in the management of low back pain. A 2008 study published in Pain, for example, found that an eight-week meditation program led to an improvement of pain acceptance and physical function in patients with chronic low back pain. The study included 37 older adults, with members meditating an average of 4.3 days a week for an average of 31.6 minutes a day.

Thank you for providing a list with creams that aren’t simply analgesic! Most lists are just full of creams that provide analgesic properties by blocking pain receptors. It doesn’t really help your body repair from damage or strain. I use a cell-regenerative, anti-inflammatory cream with analgesics and its completely natural. It has the MSM and Arnica. I apply it before I work out and after to help nurture and heal my muscles & joints as well provide pain relief. This way I recover faster and get into the gym quicker knowing my body is supported and I am not just exasperating a problem.
The first generic (cheaper) equivalent of Voltaren® Gel entered the marketplace in 2016, produced by Amneal Pharmaceutical. It should be widely available now. Both products are still prescription-only in the US, but fortunately they are over-the-counter almost everywhere else (there’s a rack of tubes of Voltaren by the till at my neighbhourhood drugstore).

Even though it is important to strive for quality when shopping for different types of products on the market, it is equally important that you think about your budget before making any purchase. Make sure that what you buy like, in this case, the anti-inflammatory cream does not overstretch your existing budget. Once you find the brand that is within your price range, the next thing to ascertain to would be to ensure that the reasonably priced brand is effective and would not have adverse side effects on your health. Nevertheless, just keep in mind that there are counterfeits products available on the market. Therefore, it is vital to watch out for such products so that you do not become a victim of purchasing counterfeit goods so that you would have not only wasted your money but you may end up with a product that may have dire consequences to your health. The best way you could avoid being duped with the unscrupulous dealers is by consulting with your doctor who would advise you best on the anti-inflammatory cream that would adequately serve your needs regardless of the price at which it might be sold on the market.
The evaluation of nutraceutical preparations with appropriately designed controlled studies has exploded in recent years. There is now a greater degree of confidence based on controlled study design and improved quality of the investigators that has strengthened positive findings found using natural compounds to treat diseases. It is important for healthcare practitioners to learn about these scientific studies to counsel patients who are taking various dietary supplements, herbs minerals and vitamins for both disease treatment and prevention.
In summer 2018 I had my first personal experience with dramatic relief from Voltaren Gel (topical diclofenac). It’s not the first time I have found it useful, but it was the first time it was amazing. I’d been having some unexplained knee pain intermittently for several weeks when it kicked up a notch or two and became constant and even started waking me up at night. When I finally remembered to try Voltaren Gel — I’m not sure what took me so long — things were bad enough that it was going to be obvious if it worked. And it was! After many days of constant discomfort ranging from 3-6 on a 10-scale, it just ended: half an hour after applying the stuff, I simply didn’t have that problem anymore. Hallelujah! It’s been weeks since then with no relapse. Although the pain was not terrible, this is actually one of the clearest examples of pain relief from any treatment that I’ve ever enjoyed.

Menthol, Levomenthol, Eucalyptus, Camphor and Oil of Wintergreen are often added to topical joint treatments. These essential oils are absorbed into the skin and stimulate skin receptors to produce either a warm sensation or a cooling sensation as they numb the pain. They work by overwhelming nerve endings with these sensations so pain messages do not get passed on. This is known as a counter-irritant effect. Wintergreen is also a rich source of methyl salicylate, a natural anti-inflammatory painkiller related to aspirin. These essential oil creams and gels tend to have names such as Deep Heat or Deep Freeze to describe how they feel during use.
When used together, menthol and methly salicylate create vasodilation (opening of the blood vessels) close to the surface of the skin.  Increased blood flow to the area of application is said to have pain-killing on the nerve receptors in the treated area.  When combined, these two ingredients also work together to form a class of treatment called counterirritants. Counterirritants work by tricking the body into feeling sensations other than pain. The menthol and methyl salicylate in muscle creams create conflicting feelings of warmth and cold. When the nervous system sends both of these sensations, at the same time, they compete with and ultimately block pain signals from travelling to the brain.  Together these ingredients, when delivered in muscle creams or sports balms, work to create a powerful 1-2 punch, killing pain and providing relief to aching muscles and joints.
I have had an Osteo Arthritic left knee for 12 years since a car accident. I have had surgery on it twice. I have Cortisone Injections in it every 90 days. I am 62.. I also have been diagnosed with Rheumatoid Arthritis and SLE Systemic Lupus which means that I have long periods of fatigue and my autoimmune system does not function properly. My left knee will need replacement in 2 to 3 years. Long story short......I needed a good external rubbing cream for my knee joint to manage world class pain. So far ......Synthaflex Joint Cream has been the best product that I have purchased and used. I rubbed it in with a paper towel because it has the old fashioned peppermint heat feel....so you do not want it on your hands. Keep it away from your face and your eyes because it will burn. It is a white cream. It takes effect instantly and lasts with my usage for about 5 hours. I use it twice per day. It has worked so well since I received it last week that I am getting ready to order two more jars tonight. I will post updates over the coming months but as of week one I strongly recommend this product. I have far less pain walking and no pain sitting or resting so far.
Green tea research now demonstrates both anti-inflammatory and chondroprotective effects. Additionally, green tea research includes the “Asian paradox”, which theorizes that increased green tea consumption in Asia may lead to significant cardiovascular, neuroprotective and cancer prevention properties.[113] The usual recommendation is 3–4 cups of tea a day. Green tea extract has a typical dosage of 300–400 mg. Green tea can cause stomach irritation in some, and because of its caffeine content, a decaffeinated variety is also available; but the polyphenol content is currently unknown.[2,49,53,108,112,117,120]
Meditation and mindfulness. Mindfulness meditation, which focuses on awareness of the present moment, can reduce the way we perceive pain. In one study, only four days of training led to a 40% reduction in pain rating and a 57% reduction in pain-unpleasantness.[14] This kind of meditation can help you to control back pain, fibromyalgia, and migraines. Read more about meditation and mindfulness for pain control here.
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