The Inactive ingredients are aloe barbadensis leaf extract, arnica Montana flower extract, Actium lappa root (burdock) extract, boswellia carterii resin extract, calendula officinalis extract, carbomer, camellia sinensis (green tea) leaf extract, camphor, glycerin, ilex paraguariensis leaf extract, isopropyl alcohol, isopropyl myristate, melissa officinalis (lemon balm) leaf extract, silica, tocopheryl (vitamin E) acetate, triethanolamine, water, blue 1, and yellow 5. Ilex is a skin protectant for topical skin barrier gels and lotions designed to protect the skin from harmful irritants such as urine and feces. It usually contains good things such as corn starch, white petroleum jelly, and zinc oxide.

In a 2011 research review published in the British Journal of Anaesthesia, investigators looked at the available research on the use of topically applied capsaicin in the treatment of several types of chronic pain. This included two clinical trials examining back pain, both of which found that capsaicin helped reduce low back pain without causing notable side effects.

Prolotherapy treatments work by naturally promoting a minor inflammatory response near damaged connective tissue, promoting regeneration and the growth of new, healthier tissue in the process. These treatments have been used to effectively reduce or heal chronic musculoskeletal conditions of the back, such as herniated/bulging discs, arthritis, osteoarthritis or other chronic joint pains, and tendonitis that affects the lower body and causes compensations in the spine. (7) For the most benefits, it seems that prolotherapy works best when combined with other back pain treatments, such as spinal manipulation, exercise and in some cases medications when needed.
Schematic showing another inflammatory pathway that is activated by tissue injury. This is the NF-kB activation, in which once the protein is free as a result of tissue injury, it can enter the cell nucleus and activate the DNA to enhance the inflammatory response further by the production of additional cytokines, chemokines, and adhesion molecules (IKKB = IkB kinase)

The benefits of heat therapy are twofold: it increases the flow of healing oxygen and nutrients to the damaged area, and it suppresses pain signals. Some find that wearing a heat wrap, such as those from ThermaCare, is best because it releases a low level heat for several hours and can be worn under clothes so you can remain mobile. You can also combine the benefits of aromatherapy and a heat by adding an essential oil to the hot pack; you can experiment by making your own microwaveable heating pad at home and adding different essential oils to see what works best for you.
I have had an Osteo Arthritic left knee for 12 years since a car accident. I have had surgery on it twice. I have Cortisone Injections in it every 90 days. I am 62.. I also have been diagnosed with Rheumatoid Arthritis and SLE Systemic Lupus which means that I have long periods of fatigue and my autoimmune system does not function properly. My left knee will need replacement in 2 to 3 years. Long story short......I needed a good external rubbing cream for my knee joint to manage world class pain. So far ......Synthaflex Joint Cream has been the best product that I have purchased and used. I rubbed it in with a paper towel because it has the old fashioned peppermint heat feel....so you do not want it on your hands. Keep it away from your face and your eyes because it will burn. It is a white cream. It takes effect instantly and lasts with my usage for about 5 hours. I use it twice per day. It has worked so well since I received it last week that I am getting ready to order two more jars tonight. I will post updates over the coming months but as of week one I strongly recommend this product. I have far less pain walking and no pain sitting or resting so far.

One of the problems with pain relief creams is that application can become messy. It can be difficult to keep the cream contained to the area of skin that needs treating, and if you get the product on your hands, it’s easy to accidentally rub it into the eyes, which can be painful! To the rescue: Roll-on formulas, like Outback All-Natural Pain Relief, which allow for hands-free and targeted pain relief. The product contains just four ingredients: tea tree oil, vanilla, eucalyptus, and olive oil. The ingredients ease pain by reducing inflammation.
How it works: When back muscles hurt, the pain is usually caused by inflamed tissue. Cold reduces the swelling and discomfort, says Jason Highsmith, a neurosurgeon in Charleston, South Carolina. As soon as you feel pain, apply cold several times a day, 10 minutes at a time, for about three days. A bag of frozen peas works, or try a cold pack, like an Ace Reusable Cold Compress ($10 at drugstores).
Many arthritis creams have a telling medicinal smell, but you won’t get that from this Blue Emu cream. Like other arthritis creams on the market, it contains glucosamine and MSM. What stands out about this one, however, is that it contains emu oil (thus the name), which promises to penetrate deeply into the skin and provide soothing relief to joints and muscles. Thousands of customers say it delivers on those promises too.
A type of enzyme extracted from pineapple stems, bromelain reduces levels of prostaglandins, which are hormones that induce inflammation. Bromelain may benefit people with arthritis and conditions associated with musculoskeletal tension (such as TMJ syndrome), as well as those suffering trauma-related inflammation. What's more, the enzyme may promote healing in muscles and connective tissues.
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Its active ingredients include eucalyptus oil and tea tree oil, but nothing that will heat up your skin or provide the icy, cooling sensation that some other arthritis creams do. It comes in a roller-ball format, which you use to massage the product into the skin. Devoted fans say it’s the best pain-relief cream on the market, and they love that it doesn’t come with a lingering medicinal scent.
Carun Active Hemp Ointment is an infusion of cannabidiol CBD in petroleum jelly, hemp seed oil and olive oil, and is scented with a blend of natural lemon, peppermint and lavender essential oils. This ointment contains CBD at a strength of 3% (a 100ml pot contains 300mg CBD) and has a soft, melting texture at room temperature. Carun Active Hemp Ointment is available from Amazon.co.uk. A wide range of CBD ointments and creams are also available on Amazon.com some of which combine CBD with Arnica for additional healing benefits.
Over-the-counter (OTC) pain relievers. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve), might relieve acute back pain. Take these medications only as directed by your doctor. Overuse can cause serious side effects. If OTC pain relievers don't relieve your pain, your doctor might suggest prescription NSAIDs.
Also, many painful factors in neck, back and muscle pain are deep inside the body — probably much deeper than Voltaren® Gel can “reach.” For instance, if your low back pain is coming from the facet joints — small joints deep in the spine, under a thick layer of muscle — chances are that a topical treatment simply doesn’t stand a chance of having an effect.
Looking for a nonaddictive way to soothe aches? LifeSeasons’ award-winning Pain Bloc-R helps deliver the benefits of conventional approaches, including decreased aches and discomforts and increased relaxation, without the common pharmaceutical side effects. Pain Bloc-R combines natural ingredients and compounds, including Angelica dahurica, white willow bark, L-tetrahydropalmatine, and L-theanine, that work together to help support the body’s natural ability to relieve everyday aches.

In addition to the other methods and strategies discussed throughout my book, I recommend taking natural remedies that reduce pain and inflammation, protect joint health and promote healing without side effects. Below I offer an overview of 20 different supplements formulas or ingredients often found within such formulations. Read each, keeping in mind your specific condition and how some may be more effective for you than others.
Turmeric. This spice has been used to relieve arthritis pain and heartburn, and to reduce inflammation. It's unclear how turmeric works against pain or inflammation, but its activity may be due to a chemical called curcumin, which has anti-inflammatory properties. Turmeric is usually safe to use, but high doses or long-term use may cause indigestion. Also, people with gallbladder disease should avoid using turmeric.
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