I have nerve pain , spinal stenosis and no longer able to take oral medication that did help with symptoms but caused me to have allergic reactions .After stopping the oral medication I suffered with pain radiating from my lower back to my feet . At night I could not sleep. I am so glad that I found this miracle in a jar . I am sleeping very good at night without pain .It really do help with all my symptoms. I discussed the benefits of this with my doctor and have told family & friends .
I have had an Osteo Arthritic left knee for 12 years since a car accident. I have had surgery on it twice. I have Cortisone Injections in it every 90 days. I am 62.. I also have been diagnosed with Rheumatoid Arthritis and SLE Systemic Lupus which means that I have long periods of fatigue and my autoimmune system does not function properly. My left knee will need replacement in 2 to 3 years. Long story short......I needed a good external rubbing cream for my knee joint to manage world class pain. So far ......Synthaflex Joint Cream has been the best product that I have purchased and used. I rubbed it in with a paper towel because it has the old fashioned peppermint heat feel....so you do not want it on your hands. Keep it away from your face and your eyes because it will burn. It is a white cream. It takes effect instantly and lasts with my usage for about 5 hours. I use it twice per day. It has worked so well since I received it last week that I am getting ready to order two more jars tonight. I will post updates over the coming months but as of week one I strongly recommend this product. I have far less pain walking and no pain sitting or resting so far.

"I don't use topical pain relievers often, but when I do I use a product called Biofreeze ($15; performancehealth.com). It's a menthol-based gel that soothes local aches and pains in much the same way that ice therapy works but with less skin irritation, and the ability to be mobile once it's applied. It's also the product physical therapists and massage therapists choose." — Yusuf Jeffers, Tone House coach
Green tea research now demonstrates both anti-inflammatory and chondroprotective effects. Additionally, green tea research includes the “Asian paradox”, which theorizes that increased green tea consumption in Asia may lead to significant cardiovascular, neuroprotective and cancer prevention properties.[113] The usual recommendation is 3–4 cups of tea a day. Green tea extract has a typical dosage of 300–400 mg. Green tea can cause stomach irritation in some, and because of its caffeine content, a decaffeinated variety is also available; but the polyphenol content is currently unknown.[2,49,53,108,112,117,120]
Aspirin is now believed to target both the NF-kB and COX pathways. These agents inhibit the NF-kB pathway in endothelial cells and block NF-kB activation to inhibit leukocyte recruitment.[114,115,116] NSAIDs have also been found to inhibit both the COX system and the NF-kB pathway. Immunosuppressant drugs also reduce nuclear expression of NF-kB.[39,70,75] Research now indicates that blocking the activation of NF-kB along with other inflammation mediators [Table 2] is the major mechanism for reducing inflammation by natural compounds.

For those sore muscles and inflammation, peppermint oil and pine will relieve your aches and the chamomile and eucalyptus relieve tender feeling pain. For relieving the stress you are feeling, pink grapefruit, lemongrass, and spearmint oil will do that for you. These are all natural products providing you with vitamins A and C and antioxidants with the aloe vera providing moisture to your skin.
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The NSAIDs are also known to have adverse effects on kidney function.[31] Dehydration or preexisting chronic renal failure or disease, resulting in stimulation of the renin–angiotensin system, may predispose certain populations to acute renal failure through inhibition of prostaglandin synthesis, which can occur when taking NSAIDs.[31] The National Kidney Foundation asserts that approximately 10% of kidney failures per year are directly correlated to substantial overuse of NSAIDs.
Often patients will experience a different response in treatment with a different medication. This could be why some medications have helped your symptoms while others do not have a significant effect. This is not unusual, and it is difficult to predict which medications will most benefit a given individual. The best way to determine which NSAID is best for you is to try different options. Often a physician will recommend one NSAID, and if adequate relief of symptoms is not obtained within several weeks of treatment, another NSAID can be tried.
Maybe. They may not completely get rid of your monster headache but they may help relieve some of the aches that come with them. Some people who experience migrains also have neck and shoulder pain and topical pain relief gels and creams may help to lessen this symptom. Some migraine sufferers use roll-ons on the forehead or back of the head to induce a cooling or heating sensation to help cope with the pain.
Side effects from topical medications include redness, itching, and other skin irritation. They are generally mild—and uncommon. The cause of skin irritation is often the material used to make the cream or gel, not the NSAID, says Dr. Joanne Borg-Stein, medical director of the Harvard-affiliated Spaulding-Wellesley Rehabilitation Center in Massachusetts. When that happens, it’s possible for a pharmacist to create a preparation with ingredients that are less irritating to your skin.
For natural headache relief, two essential oils team up for natural pain relief. Peppermint oil improves circulation and lavender reduces muscle tension — two ways to quickly stop a headache in its tracks. Try placing a few drops of peppermint or lavender oil into your hands and then rubbing the blend on your forehead, temples and back of neck. You can also dilute a few drops down by mixing the essential oils with almond, grapeseed or coconut oil.
Turmeric. This spice has been used to relieve arthritis pain and heartburn, and to reduce inflammation. It's unclear how turmeric works against pain or inflammation, but its activity may be due to a chemical called curcumin, which has anti-inflammatory properties. Turmeric is usually safe to use, but high doses or long-term use may cause indigestion. Also, people with gallbladder disease should avoid using turmeric.
I am in my mid 50’s and was recently diagnosed with arthritis in both my knees. My left knee was the absolute worse. Seems squats and lunges are the worst for arthritic knees and my worst pain followed these exercises. Since then I have gotten a personal trainer so that I won’t hurt myself trying to workout. Anyway, I am a 5k runner and I want to continue. But let me tell you guys about the topical regimen that I am using that I employed just short of going to get a cortisone injection. Magnesium Oil, MSM lotion and organic silica gel. I got all of these products from an on-line source of organic foods, products and such. I absolutely love their products and these 3 products have made my knee feel like I never was diagnosed with arthritis, and I’ve been following this morning and night application of the 3 products for a little over two weeks now. Let me tell you, I couldn’t sleep at night because of the pain. Now it’s the difference between night and day. I hope this helps someone
After an injury, first rest, ice the area, use compression, and elevate the area. The acronym to help you remember is RICE. Rest the area. Ice the area 4 times a day for 10 to 15 minutes. If it looks better, compress the area with an Ace-type elastic bandage. To reduce swelling, ice helps, and so does elevating the area above your heart. When the swelling is down but you still have mild pain, apply a topical cream or gel according to the package directions. If it has worsened, consult your doctor.
I am a science writer, former massage therapist, and I was the assistant editor at ScienceBasedMedicine.org for several years. I have had my share of injuries and pain challenges as a runner and ultimate player. My wife and I live in downtown Vancouver, Canada. See my full bio and qualifications, or my blog, Writerly. You might run into me on Facebook or Twitter.

Voltaren® Gel (topical diclofenac) is a particularly safe and useful medicine. It’s an anti-inflammatory cream, so it can be applied only where you need it, instead of soaking your entire system with a medication, avoiding or dramatically reducing common side effects like indigestion, as well as some serious safety concerns associated with oral diclofenac. In the US, this drug is FDA-approved to treat osteoarthritis in “joints amenable to topical treatment, such as the knees and those of the hands,” but it probably also works for some other painful problems, such as some repetitive strain injuries and back pain. The evidence shows that it “provides clinically meaningful analgesia.” So this product actually works and gets a pass from skeptics and critics — a rare thing in the world of pain treatments!
The packaging for this Outback cream doesn’t look like that of your typical arthritis cream, and thousands of customers say it doesn’t work like one either. They say, in fact, that Outback works better than them. It was developed by Dave Ireland, aka the Wildlife Man, who couldn’t find relief from his arthritis pain, so he developed this and put his picture on it.
There's a reason there are so many roll-ons on this list. They're super handy and easy to use. This CobraZol gel provides quick relief that lasts up to 10 hours. It's a good choice for both chronic and acute pain. This gel comes in a 2 oz format. Believe it or not, this stuff actually contains cobra venom. Venom apparently is thought to help de-active pain pathways and reduce pain. This roll-on is a great way to manage pain and help users wean off of more serious and potentially dangerous pain medications.
Hi Patricia, Sorry to hear about your experience. The patient information leaflet for diclofenac gel inside each pack advises that users should avoid applying on large areas of skin, that an amount ranging in size from a 1 penny to a 2 pence piece will usually be sufficient, and not to use it if you are already taking NSAID tablets. High blood pressure is not listed as a possible side effect, as this was not detected in clinical trials. As you say, diclofenac tablets and other oral NSAIDs are now associated with an increased risk of cardiovascular disease which is why the gel is considered a better option. I have coverd this in a post about ibuprofen increasing blood pressure here. Research looking into the long-term tolerability of topical diclogenac gel in people with an elevated risk of NSAID-related side effects, such as existing high blood pressure, type 2 diabetes, stroke and heart disease, suggests that the gel appears to be safe to use to treat osteoarthritis, even in these high risk groups. Having said that, everyone is different, due to the genes they have inherited, and you may have experienced an unusual, idiosyncratic reaction to the small amounts absorbed via the skin. It’s good that you or your doctor were monitoring your blood pressure to detect this. I have a website dedicated to lowering a high blood pressure, which includes lots of complementary approaches, that you may find helpful. Are you able to share the name of the herbal cream which you have found works better? Best wishes, Sarah B
When anti-inflammatories are taken by mouth they work by blocking (inhibiting) the effect of chemicals (enzymes) called cyclo-oxygenase (COX) enzymes. COX enzymes help to make other chemicals called prostaglandins. Some prostaglandins are involved in the production of pain and inflammation at sites of injury or damage. A reduction in prostaglandin production reduces pain and inflammation.
What makes a joint “amenable”? Is it mellow and easy-going? No, just accessible: a pain-killing gel is useful only for joints that aren’t covered by a thick layer of muscle (like the shoulder). The medication gets diluted as it penetrates deeper into tissue, and a meaningful amount can only get into joints if the joint is just under the surface of the skin.
Capsaicin. The main ingredient of hot chili peppers, capsaicin is also one of the most effective ingredients for topical pain relief.It can be helpful for joint pain and for diabetic nerve pain. When first applied, capsaicin creams cause a warm tingling or burning sensation. This gets better over time. You may need to apply these creams for a few days up to a couple of weeks before you notice relief from pain.

This substance comes from edible hot peppers and helps to reduce a substance in the body that works to produce pain. Be careful with gels and creams that contain this substance, you must wash your hands after using, especially before touching sensitive areas of the body. Some people may also experience adverse reactions to this ingredient. When first using a gel or cream with capsaicin use just a small amount in a small area to see how you react to it.

From tissue spasms to neurological aches and from shooting aches to twist, this best muscle rub cream of Living Well Nutraceuticals is lab-accredited to heal all patterns of pain. Its exquisiteness is essentially fortified by the presence of Cetyl Myristoleate or CMO that enacts in depth over swelled up muscles, tendons and joints and eradicates the very inflammation—the root cause of all pains. The best muscle rub cream also owns Methylsulfonylmethane or MSM, which again reaches into the body cells and opens those up to prevent the aches affecting physique. The ointment is moreover nurtured with cruxes of Belladonna and Rhus Tox and caters enduring soothe. It comes in a 3oz density tube.
Rubbing the pain relief cream on the affected area reduces the pain quickly. When you rubbing the cream or gel on the affected area then it warms the spot and increases the blood flow. The bodily action of massaging or rubbing allows the active ingredients to absorb into the affected skin smoothly. So you feel relaxed from severe pain such as back pain or knee pain.
Topical diclofenac gel (Voltarol) is highly effective for treating muscle and joint aches and pains. In fact, a direct comparison of topical non-steroidal anti-inflammatory diclofenac gel with an oral equivalent did not show any difference in their ability to reduce pain and stiffness. Data from 34 studies, involving over 7,600 people, suggests that the topical NSAID, diclofenac, is the most effective form of non-steroidal anti-inflammatory painkiller for applying to the skin to treat muscle and joint pain.
Endorphins are hormones made naturally in your body. What most people don't know is that they can be just as strong as any manufactured pain medication. When endorphins are released in your body, they help block pain signals from registering with your brain. Endorphins also help alleviate anxiety, stress, and depression, which are all associated with chronic back pain and often make the pain worse.
This substance comes from edible hot peppers and helps to reduce a substance in the body that works to produce pain. Be careful with gels and creams that contain this substance, you must wash your hands after using, especially before touching sensitive areas of the body. Some people may also experience adverse reactions to this ingredient. When first using a gel or cream with capsaicin use just a small amount in a small area to see how you react to it.
Yes, most of these creams can either be used on a daily basis or long-term basis. Nevertheless, at any given point in time, always ensure that you consult with your doctor to find out how often it would be advisable to use such forms of medication. The best quality ones are the ones that would be FDA approved and natural. Therefore, you should use these types of medication for as long as the health practitioners advise.
Back pain is one of the most common reasons why people visit a health care provider. The good news is that the pain often goes away on its own, and people usually recover in a week or two. Many people want to stay in bed when their back hurts. For many years, getting bed rest was the normal advice. But current studies recommend no bed rest at all and stress that staying in bed longer than 48 hours not only won’t help but it may, in fact, actually delay your recovery. Here’s why:
The Biofreeze® pain relief gel is available in 16-, 32-, or 128-ounce bottles and is offered as the colorless or original green formula. The company has been making pain relief products for over 25 years. It is the #1 product that has been clinically used by professional healthcare hands-on providers, massage therapists, physical therapists, chiropractors, foot doctors (podiatrists), athletic coaches, instructors, and trainers. This is considered the best pain relief cream for muscle pain perfect for athletes. When professionals have over a hundred clients each week, the economical 128-ounce jug might be best for you for not running out. You always want it on hand for clients with sore aching body parts.
Soft tissue therapies help treat the underlying causes of back pain, such as poor posture, muscular compensations, and weakness through manipulative, hands-on adjustments. These natural therapies can help “turn on” muscles that have been “turned off” due to past injuries and therefore eliminate added stress on painful parts of the back or legs. I recommend finding a practitioner who offers one of the following:
"I don't use topical pain relievers often, but when I do I use a product called Biofreeze ($15; performancehealth.com). It's a menthol-based gel that soothes local aches and pains in much the same way that ice therapy works but with less skin irritation, and the ability to be mobile once it's applied. It's also the product physical therapists and massage therapists choose." — Yusuf Jeffers, Tone House coach
Boswellia serrata is a traditional Indian Ayurvedic remedy for inflammatory conditions. It is extracted from the gum of the Indian boswellia tree and has been in use for centuries to treat joint pain and inflammation. It provides anti-inflammatory activity in areas where there is chronic inflammation by turning off the pro-inflammatory cytokines that begin the inflammatory process. Moreover, research shows that the acids contained within boswellia extract stop the formation of immune cells known as leukotrienes, which are responsible for inflammation. This then allows blood to flow unobstructed to the joints for healing and improved mobility.
NSAIDs don’t just damage your gut lining. They affect your gut bacteria, too. A study of regular users found that different NSAIDs caused different changes in gut bacteria.[5] Ibuprofen and arthritis drug celecoxib (Celebrex), for example, increased pathogenic Enterobacteriaceae, a family of bacteria that includes E. coli, Salmonella, and a number of lesser-known bacteria that contribute to eye, skin, respiratory, and urinary tract infections.[6]
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