Patient information articles published in both the Journal of North American Spine Society and the Journal of the American Medical Association found evidence that spinal manipulations were safe, effective, drugless forms of professional treatment for both acute (short-term or sudden) and chronic low back problems in adults. (2, 3) Egoscue, another type of postural therapy protocol that focuses on fixing musculoskeletal misalignments, may also be able to help reduce and prevent back pain.
“My husband and I prefer more natural, holistic pain relievers, and we were thrilled when we found Relief cream. We take it with us everywhere we go, use it religiously for joint pain, and recommend it to everyone we know. Relief is FAR superior to Biofreeze; there truly is NO comparison. Relief smells better, feels better, and just plain works better. Thank you so much for a natural alternative to pain medications that come with some really nasty 'side effects.'” *

How much do you have to use at once and how often? Is it easy to apply too much? Generally, roll-on applicators are the best choice for reducing waste since it’s hard to put on too much when using them. It is also important to note that if you need deep muscle penetration roll-ons often don’t provide the same effect as hand rubbing gel or cream into the affected area. So be sure to keep that factor in mind as you review these products.
Collagen—particularly Type II collagen—is the main structural building block of joint cartilage. The human body is made up of 60 percent Type II collagen, and Hydrolyzed Type II collagen contains the amino acids found in human cartilage. Your body uses these amino acids to create new collagen—and repair your cartilage and connective tissue throughout your body. Hydrolyzed Collagen Type II also contains Hyaluronic Acid, which lubricates your joints and makes it an effective natural remedy for inflammation.
Acetylsalicylic acid works by irreversibly disabling the COX enzymes to block the cascade [Figure 1]. NSAIDs have evolved from blocking both COX-1 and COX-2 to selectively only blocking COX-2 in order to inhibit the inflammatory response and reduce the production of inflammatory prostaglandins and thromboxanes. The major push to develop the selective COX-2 inhibitors has been the recognition of significant complications associated with the nonselective COX-1 and COX-2 NSAIDs. Nonselective NSAIDs’ major side effects include significant gastrointestinal upset, gastritis, ulceration, hemorrhage, and even death. By locking COX-1, which also normally acts to protect the gastrointestinal mucosa, nonselective NSAIDs and aspirin can cause significant gastric tissue damage.[34,51,78,91,3,101,115]
A study involving 120 people with acute upper or lower back pain showed that rubbing in comfrey cream, three times a day for 4 to 6 days, reduced pain intensity by 95%, compared with just 38% reduction for inactive ‘placebo’ cream. Comfrey works quickly, providing good pain relief within an hour of application. In fact, researchers have found that comfrey cream is more effective than a prescribed, non-steroidal anti-inflammatory treatment (diclofenac gel) for treating ankle sprains.
Capsicum annum is a small spreading shrub which was originally cultivated in the tropical regions of the Americas but is now grown throughout the world, including the US. The small red fruit commonly used to accentuate chili owes its stinging pungency to the chemical, capsaicin. This was isolated by chemists more than a century ago and constitutes approximately 12% of the chili pepper. This fruit has been used for various medicinal purposes by the native peoples of the American tropics for hundreds of years.
Magnesium supplements can help curb the pain of migraines, muscle spasms and fibromyalgia. “It’s really easy to be magnesium deficient,” Tanya Edwards, MD, medical director of the Center for Integrative Medicine at the Cleveland Clinic, told WebMD. Heavy consumption of alcohol lowers magnesium levels. “The foods that are highest in magnesium are things like sunflower seeds and pumpkin seeds. Most of us just don’t eat those very often.”
“I cannot even tell you how AMAZING this stuff is. I never do reviews, but this product most certainly deserves one. I have dealt with MANY injuries, I was in a bad car wreck, and I have had more surgeries than I could count on both hands. My main area of pain is my upper back and neck. I have bulging disks, cervical stenosis, degenerative disk disease that causes horrible spasms, swelling, tension, and PAIN. I also have cancer and several other issues that put my pain level over the top every day. I have seen neurosurgeons, all of whom say they will eventually need to operate. I have done absolutely every possible treatment other than a spinal fusion, have had probably 10 injections, and they even went and tried to burn the nerve endings throughout my entire cervical spine, yet nothing worked. I can't even begin to tell you the medications the doctors have tried, each of which help some, but you get to a point where you don't want to constantly take medications forever. One day I was at my spine doctor's office and they had a bottle of Relief pain cream on the counter. While I was waiting there I asked the staff some questions about Relief and thought "yea, yea, but can I try it?" So, I put some on, and thought, "HOLY COW! What is this! Whatever this is, it's amazing!" Then and there I literally bought the rest of the supply they had on-hand because I couldn't believe how much it helped relieve my pains and aches. That night, I couldn't sleep because I was in so much pain, and none of my medications were helping. I felt like I was dying. So again, I put on some Relief cream and it helped soooo much. Since that day I never, ever, go anywhere without Relief! I will use this pain cream forever and continue to tell everyone I know about it because it truly works! I'm so glad I randomly tried this stuff at the doctor's office because I finally found something that gives true RELIEF!!” *
Capsaicin. Derived from hot chile peppers, topical capsaicin may be useful for some people in relieving pain. "Capsaicin works by depleting substance P, a compound that conveys the pain sensation from the peripheral to the central nervous system. It takes a couple of days for this to occur," says David Kiefer, MD, assistant clinical professor of medicine at the Arizona Center for Integrative Medicine.
Hi Peggy, It’s not a treatment with which I am familiar. Looking at the incredients, Blue Ice contains alcohol which will cool by evaporating, an aspirin-like substance (methyl salicylate), magnesium (muscle relaxant) and capsicum which has a pain killing action by depleting nerve endings of nerve chemicals. It looks like it is effective for muscle and joint pain and has good reviews but I can’t speak from personal experience. Hope that helps, Sarah B

Prostaglandins act as short-lived localized hormones that can be released by any cell of the body during tissue, chemical, or traumatic injury, and can induce fever, inflammation, and pain, once they are present in the intercellular space. Thromboxanes, which are also hormone activators, can regulate blood vessel tone, platelet aggregation, and clot formation to increase the inflammatory response.[92,82] The inflammatory pathway is a complex biochemical pathway which, once stimulated by injury, leads to the production of these and other inflammatory mediators whose initial effect is pain and tissue destruction, followed by healing and recovery.[34,51] A major component of the inflammatory pathway is called the arachidonic acid pathway because arachidonic acid is immediately released from traumatized cellular membranes. Membrane-based arachidonic acid is transformed into prostaglandins and thromboxanes partly through the enzymatic action of cyclooxygenase (COX)[34,57]. There are two types of COX enzymes, COX-1 and COX-2. Both the enzymes act similarly, but selective inhibition (as accomplished by selective COX-2 inhibiting NSAIDs) can make a difference in terms of side effects.
Chondroitin sulphate is produced naturally in the body to promote the formation of healthy cartilage, tendons and ligaments, and it is also an important component of joint synovial fluid. As you get older, your joint cells secrete less and less chondroitin and this has been linked with reduced cartilage quality and the start of degenerative changes.
It is therefore necessary to resort to another type of product which are less harmful for our bodies. One of the most effective products, which is widely backed up by scientific studies, is the arnica plant extract. The most widely used plants with local anti-inflammatory action in phytotherapy are arnica (Arnica montana) and, in a distant second place, devil’s claw (Harpagophytum procumbens).

Resveratrol is available commercially as a dietary supplement capsule, generally from the P. cuspidatum source. The trans-resveratrol is the active form, and although there is not an established dosing range, the typical dose is from 50 to 500 mg daily. Any significant side effect or safety issues with resveratrol have not been established, but due to an experimentally shown anti-platelet effect, caution should be exercised when taking other prescription or herbal anti-platelet or coagulation altering products.[29,54,59,68,72,107,109]
In one study of 28 women with osteoarthritis pain, half of the women listened to a 10 to 15 minute recorded script twice daily that guided them through muscle relaxation techniques. Women in the guided imagery group showed statistically significant improvements in their pain levels and mobility within 12 weeks, versus women in the control group who did not see any improvements.4
According to recommendations of the Arthritis Foundation, when treating conditions related to arthritis it is best to use “fish oil capsules with at least 30 percent EPA/ DHA, the active ingredients. For lupus and psoriasis, 2 grams EPA/DHA three times a day. For Raynaud’s phenomenon, 1 grams four times a day. For rheumatoid arthritis, up to 2.6 grams fish oil (1.6 grams EPA) twice a day.”
Studies have shown that the gel from this medicinal plant is able to relieve the pain and improve joint movement and stiffness in individuals with arthrosis in the fingers at the same level as ibuprofen. It demonstrates that arnica is an effective alternative to the use of NSAIDs (such as ibuprofen) against this type of conditions, as arnica also prevents the gastric irritation caused by treatment with ibuprofen. Its use is therefore particularly recommended in individuals with stomach problems.

For short-term pain relief, over-the-counter pain relievers including acetaminophen and NSAIDs (non-steroidal anti-inflammatory drugs) are sometimes suggested. The most common NSAIDs include aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve). Potential side effects of NSAIDs include stomach and liver problems. Talk to your doctor if you don't find relief after taking the recommended dose.


Can inversion therapy help with back pain? Inversion therapy, where a person is held upside down for several minutes, is an alternative therapy for back pain. They may use gravity boots or an inversion table or chair to reduce the pressure on their spine. Evidence for the effectiveness of this technique is mixed. Learn more about the benefits and risks here. Read now
China, Korea and Japan grow a vine known as Thunder God, which is one of the powerful natural relievers of arthritis, especially rheumatoid arthritis. It has properties that regulate the immune system and naturally reduce inflammation, thus being good for autoimmune diseases. One clinical trial carried out at the University of Texas Southwestern Medical Center discovered that roughly 80 percent of those patients who were given a high dose of the plant supplement found that their rheumatoid arthritis symptoms got better considerably making it well worth a try for those looking for natural remedies for inflammation and pain.
Our writers spent 5 hours researching the most popular arthritis creams on the market. Before making their final recommendations, they considered 30 different creams overall, screened options from 20 different brands and manufacturers, read over 50 user reviews (both positive and negative), and tested 1 of the creams themselves. All of this research adds up to recommendations you can trust.

Nonsteroidal anti-inflammatory medications are one of the most commonly used types of medications for musculoskeletal conditions. NSAIDs can be effective for a wide variety of orthopedic conditions from arthritis, tendinitis, or other inflammatory conditions. Determining the best NSAID for your condition may depend on a number of different factors, and what works well for one individual may not be the best medication for another. There are possible side effects of different NSAID medications the patient should be aware of, and you should discuss with your physician if taking these medications for more than a short period of time.
Bark from the white willow tree is one of the oldest herbal remedies for pain and inflammation, dating back to ancient Egyptian, Roman, Greek, and Indian civilizations, as an analgesic and antipyretic agent. Because of the gastric side effects of aspirin, there has been a resurgence in the use of white willow bark for the treatment of inflammatory syndromes. The mechanism of action of white willow bark is similar to that of aspirin which is a nonselective inhibitor of COX-1 and COX-2, used to block inflammatory prostaglandins.[48]
Diclofenac is an extremely popular drug — again, we’re talking oral here — and it is associated with serious cardiovascular risks: “There is increasing regulatory concern about diclofenac. … Diclofenac has no advantage in terms of gastrointestinal safety and it has a clear cardiovascular disadvantage.”14 This has been in the news quite a bit, and NPR had a hit in 2013 with this headline: “World's Most Popular Painkiller Raises Heart Attack Risk.”
Just how does acupuncture work? According to traditional Chinese medicine, pain results from blocked energy along the meridians of the body, which are unblocked when acupuncture needles are inserted along these invisible pathways. Acupuncture may also release natural pain-relieving opioids, send signals to the sympathetic nervous system, and release neurochemicals and hormones.
A type of enzyme extracted from pineapple stems, bromelain reduces levels of prostaglandins, which are hormones that induce inflammation. Bromelain may benefit people with arthritis and conditions associated with musculoskeletal tension (such as TMJ syndrome), as well as those suffering trauma-related inflammation. What's more, the enzyme may promote healing in muscles and connective tissues.
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