I am allergic to anti-inflammatory pills since they affect my stomach. I don't like the bad side effects they give either. So I look to topical anti-inflammatory cream to help when I have back, hip and/or shoulders sprains and strains. I have tried endless products: Penetrex, Aspercreme, Australian dream, Celadrin and so on. Out of these, Muscle Care works best for pain management. However, I do have some skin reactions to it so I have to give it a rest. When that happens, I use Topricin which works quite well. However, to me, SynthaFlex works as well, if not better. On top of that, it gives a strong cool menthol effect which Topricin doesn't. So when I overwork some muscles, I like to use SynthaFlex and/or Topricin. When my skin reactions calm down, I go back to using Muscle Care from time to time. I also use a roller to stretch which also helps. I hope this review gives others a better sense of what might work for them.
Maybe. They may not completely get rid of your monster headache but they may help relieve some of the aches that come with them. Some people who experience migrains also have neck and shoulder pain and topical pain relief gels and creams may help to lessen this symptom. Some migraine sufferers use roll-ons on the forehead or back of the head to induce a cooling or heating sensation to help cope with the pain.
The arnica Montana plant—also known as the mountain daisy—has been used for centuries to provide natural pain relief. For people who prefer a homeopathic approach to pain, the Boiron Arnica Cream is a great addition to your medicine cabinet. The non-sticky cream can help relieve muscle pain, stiffness, swelling, and bruise discoloration. It’s also a good option for sensitive skin thanks to the natural ingredients. It can even be applied to the face and is safe to use on children.

Back pain is a health concern for most people in the United States at some point in their lives and one of the most common reasons people miss work or visit the doctor. More than 80 percent of Americans will experience low back pain, and this health problem costs the United States over $100 billion each year, most of which is a result of lost wages. 
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Pycnogenol inhibits TNF-α–induced NF-kB activation as well as adhesion molecule expression in the endothelium. Grimm et al, recently reported that oral intake of pycnogenol inhibited NF-kB activation in lipopolysaccharide-stimulated monocytes as well, thus decreasing the inflammatory response. It also statistically significantly inhibited matrix metalloproteinase-9.[46] This matrix-degrading enzyme is highly expressed at sites of inflammation, and contributes to the pathogenesis of various chronic inflammatory diseases.[96]
I am 63 with osteoarthritis of my knee. I have struggled with pain relief and steroid injection hasn’t helped now waiting for new knee but need to control pain. I have just been recommended emu oil. I went to holland and Barrett and found Blue ease gel that has emu oil, capsicum and MSN amongst its ingredients. It does help the pain but skin burns (may have put too much on) how much will I need for a knee and will the burning sensation go away I have tried capsicum cream on prescription and that advised that burning sensation improves in a couple of weeks. From reading your advise re capsicum am I right in thinking that the burning sensation distracts the brain from the joint pain thanks

Because of the significant side effect profiles of steroidal and NSAID medications, there is a greater interest in natural compounds, such as dietary supplement and herbal remedies, which have been used for centuries to reduce pain and inflammation.[94] Many of these natural compounds also work by inhibiting the inflammatory pathways in a similar manner as NSAIDs. In addition to the COX pathway, many natural compounds act to inhibit nuclear factor-kB (NF-kB) inflammatory pathways.
The use of fish oil (in the form of cod liver oil), an omega-3 EFA, for the treatment of muscular, skeletal, and discogenic diseases, can be traced back to the late 18th century as detailed by Curtis et al.,[24,25] Unfortunately, because of the rapid onset of rancidity of this polyunsaturated oil when exposed to air, and hence its disconcerting odor, cod liver oil fell out of favor. With improved extraction techniques, such as using a protective nitrogen blanket and enhanced oxygen-free encapsulation methods, there is less chance of oxidation during the manufacturing process. The therapeutic benefits of fish oil can now be realized without the regurgitation and odor of previous products caused by peroxides and rancid tasting fish oil.[14]

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Omega-3 EFA, found in fish oil, can directly reduce the degenerative enzymes, aggrecanase and matrix metalloproteinase, as well as IL-1, TNF-α, and COX-2, to reduce the inflammation in synovial cartilage. A recent study of 250 patients with cervical and lumbar disc disease, who were taking NSAIDs, revealed that 59% could substitute fish oil supplements as a natural anti-inflammatory agent for the NSAIDs.[71] The recommended dosage is a total of 1.5–5g of EPA and DHA per day, taken with meals.
Curcumin is the bioactive compound in turmeric that gives the herb its healing properties. It’s one of the safest anti-inflammatories you can take, and is an effective natural pain reliever too — even for severe pain. In fact, curcumin matches or outperforms ibuprofen, acetaminophen, and other over-the-counter painkillers without any side effects.[12]
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