15. Bromelain – This natural pain-reducer comes from the enzymes present in pineapple stems. Research shows that it reduces levels of prostaglandins, which are hormones that induce inflammation. Bromelain may benefit people with arthritis and conditions marked by musculoskeletal tension (like TMJ syndrome), in addition to those suffering trauma-related inflammation. The enzyme also promotes healing in muscles and connective tissues.
If you need stronger pain relief, talk to your doctor about a prescription topical NSAID. A prescription topical NSAID is stronger than OTC products. Topical NSAIDs also carry less risk of stomach upset, ulcers, or other problems than oral NSAIDs do. The only prescription topical NSAID currently available is called Voltaren (diclofenac). Talk to your doctor to find out if it’s right for you.
Massage. Various forms of body work can provide temporary pain relief. You can try full-body Swedish massage for  stress relief and relaxation; deep-tissue massage, which uses pressure and slow strokes on deeper muscle tissue to release knots and relieve tension; or myofascial release, which uses long, stretching strokes to relieve tension around the connective tissue of the muscles.
NSAIDs don’t just damage your gut lining. They affect your gut bacteria, too. A study of regular users found that different NSAIDs caused different changes in gut bacteria.[5] Ibuprofen and arthritis drug celecoxib (Celebrex), for example, increased pathogenic Enterobacteriaceae, a family of bacteria that includes E. coli, Salmonella, and a number of lesser-known bacteria that contribute to eye, skin, respiratory, and urinary tract infections.[6]
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