If you suffer from muscle pain, a muscle pain relief cream is a smart option. The best pain relief gel or cream will reduce your pain and get you back to doing the things you enjoy. When you lessen your pain with muscle cream, you'll sleep better and wake feeling more comfortable. With all the benefits associated with pain relief cream, there's no reason to delay purchasing some. Of course, speak with your doctor to determine which type is right for you. When you’re ready to buy, any of the products on our list are sure to relieve your pain and help you finally relax.
For natural headache relief, two essential oils team up for natural pain relief. Peppermint oil improves circulation and lavender reduces muscle tension — two ways to quickly stop a headache in its tracks. Try placing a few drops of peppermint or lavender oil into your hands and then rubbing the blend on your forehead, temples and back of neck. You can also dilute a few drops down by mixing the essential oils with almond, grapeseed or coconut oil.

Many of the 10 million Americans suffering from widespread muscle pain due to fibromyalgia look for non-prescriptions options for pain relief. As a physician with fibromyalgia myself, I want to share with you the most effective natural options that I include in my own pain relief “toolbox,” which includes anti-inflammatory herbs, topical creams, and a unique form of massage that breaks up painful muscle knots.


Ingredients:Active ingredients (in cream): Belladonna 3X, Capsicum 3X, Colocynthis 3X, Gnaphalium Polycephalum 3X, Hypericum Perforatum 3X, Magnesia Phosphorica 3X, Rhus Tox 3X. Inactive ingredients Water, Polyacrylamide, C13-14 Isoparaffin, Propylene Glycol, Methylparaben, Propylparaben, Capsicum Annuum Resin, Lavandula Angustifolia (Lavender) Oil, Salvia Officinalis (Sage) Leaf Oil, Laureth-7, Aloe Barbadensis Leaf Juice, Magnesium Ascorbyl Phosphate, Tocopheryl Acetate, Folic Acid, Retinyl Palmitate, Calendula Officinalis Flower Extract, Salvia Officinalis (Sage) Leaf Extract, Achillea Millefolium Extract, Sambucus Nigra Flower Extract, Foeniculum Vulgare (Fennel) Seed Extract, Citrus Aurantium Dulcis (Orange) Flower Extract, Rosa Canina Flower Extract, Ger anium Maculatum Extract.
With more than 23,000 reviews on Amazon, customers give Penetrex sky-high marks for effective pain relief. If it doesn’t work for you, it comes with a 100 percent, no-questions-asked, money-back guarantee. Formulated to fight inflammation, it contains a mix of ingredients including arnica, choline, glucosamine, Vitamin B6, and MSM. It’s not odor-free, but rather has a light scent that disappears quickly after you apply it. You can use it alone or in conjunction with heating pads, massagers, ice, and other therapies.
I use my Rogue Fitness Supernova ($40; roguefitness.com) for self-myofascial release (SMR). By applying pressure directly to sore muscles with my supernova, I am able to roll out knots (or adhesions) on the muscle. This allows the body to bring blood flow to troubled areas by transporting nutrients and oxygen to the muscles for faster repair." — Troy Brooks, YG Studios and founder TB Elite Fitness

Never use a topical product if you have open wounds, scratches, or broken skin to reduce risks. You don’t want to cover up these with Band-Aids. Never apply near your eyes or mucous membranes, including your private area. Be sure to follow the directions on the product. Using these products for too long can make you skin become sensitive and you might have an allergic reaction. If you use a patch and it starts to itch, burn, or your skin has a rash or is red, stop using it. You can use the product for a long time before your body becomes sensitive to one or more of the ingredients. If you have a reaction, see your healthcare provider at once. This can also happen with lotions, creams, sticks, roll-ons, and gels. Don’t keep adding more to your skin if the product doesn’t seem to work. More is not better.


Still an excellent product. It remains effective for pain relief for about 5 hours with each application for me. Make sure to rub in a good thick portion for several minutes to the entire area of pain. Each jar of Synthaflex lasts about 18 days for me with applications twice each day. It remains the best external joint and muscle pain relief rub that I have ever used.

Biofeedback. You can learn to control your body’s responses to pain triggers. In biofeedback, through sensors connected to your body, a machine will show how thoughts and actions can affect your autonomic nervous system. This controls the heart, lungs, stomach and intestines, as well as the release of stress hormones. Learning how to control breathing and heart rate will allow you to control other physical reactions, such as pain.
People who use nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as topical diclofenac (Pennsaid, Voltaren) may have a higher risk of having a heart attack or a stroke than people who do not use these medications. These events may happen without warning and may cause death. This risk may be higher for people who use NSAIDs for a long time. Do not use an NSAID such as topical diclofenac if you have recently had a heart attack, unless directed to do so by your doctor.Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke; if you smoke; and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of your body, or slurred speech.
Can stomach problems cause lower back pain? The back is a sensitive part of the body, which has many nerves and organs nearby. This means that issues such as digestive conditions can occur at the same time as back pain. Back pain and bloating are common symptoms of injury, pregnancy, or gastrointestinal problems. Treatment depends on the cause. Learn more here. Read now
If your back pain hasn't resolved itself within four to six weeks, you'll want to make an appointment with your doctor. Your doc will examine your back and ask you to sit, stand, bend, walk, and lift your legs to see how your pain is affecting your mobility. You'll likely be asked to rate your pain on a scale of one to 10, and you may be sent for imaging tests like an x-ray or MRI. You might be asked to try one of these therapies:

Within the cartilage around your joints is a chemical known as chondroitin. Chondroitin is naturally produced by the body. As you age, your natural supply starts to plummet. And a loss of chondroitin from cartilage is linked to a major cause of joint pain. Moreover, through wear and tear the joint cartilage breaks down, resulting in the condition of Osteoarthritis. We can’t regenerate cartilage on our own, but we can take a supplement called chondroitin sulfate which, studies show, can help slow down this degenerative process and help naturally reduce arthritic pain. Chondroitin sulfate is made from the cartilage of cows and other animals, and is often used in combination with other products including glucosamine and manganese.
The Boswellia species are trees located in India, Ethiopia, Somalia, and the Arabian Peninsula, and they produce a gum resin called olibanum, better known in the western world as frankincense. This resin possesses anti-inflammatory, anti-arthritic, and analgesic properties. Boswellia can inhibit the leukotriene biosynthesis in neutrophilic granulocytes by inhibiting 5-LOX, thus affecting various inflammatory diseases that are perpetuated by leukotrienes.[95] Clinically, the substance is used in the treatment of degenerative and inflammatory joint disorders. It reduces the total white blood cell count in joint fluid, and it also inhibits leukocyte elastase, which is released in rheumatoid arthritis. In one recent study, a statistically significant improvement in arthritis of the knee was shown after 8 weeks of treatment with 333 mg B. serrata extract taken three times a day. The treatment improved function, but radiographically there was no change in the affected joints.[62]
Comfrey root has a long history of traditional use to heal wounds and fractures when applied as a poultice, and was commonly known as ‘knit bone’. Modern research shows that comfrey contains two main active ingredients: allantoin which promotes tissue regeneration, and rosmarinic acid which damps down inflammation and reduces pain. Comfrey root cream is a popular and effective treatment for joint pain, sprains and strains.
The exhibited pain cream of Penetrex brand comprises an evolved pain-relieving mechanism, which in effect is crafted by availing the highly effective ingredients of Cetyl Myristoleate or CMO and Methylsulfonylmethane or MSM. Whereas the first one enacts over the ground cause of all muscular and joint aches that is inflammation, the second one works over the physiological cells and fortifies them to fight pains. Other serviceable ingredients in the formulary include Arnica, Vitamin B6 and Choline. The pain cream is non-sticky and stain-free and vowed to gratis steroids and drugs. It is especially famous for dodging aches over knee, arm, calf, hip and wrist. The parent brand vends it in a 2oz volume pot.

Despite what a majority of people may have been made to believe concerning the issue of anti-inflammatory creams and the pain-relieving creams the truth is that the two types of creams differ immensely. Pain relief creams serve the important function of disrupting the transmission of pain signals from different parts of the body to the brain thus allowing you to feeling a sense of temporary pain relief. However, most cream pain relievers would not have elements that would help reduce inflammation or swelling. Nevertheless, the anti-inflammatory creams and the pain relief creams both can be used for arthritis flare-ups and dealing with minor sports injuries. Nevertheless, for those people who may have never used these types of medications before or those who may not be sure of the type to use it is important to consult with the doctor before using such a product. Most all, never use the anti-inflammatory creams on a child or expectant mother unless who check in with your doctor.

Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.
Also, many painful factors in neck, back and muscle pain are deep inside the body — probably much deeper than Voltaren® Gel can “reach.” For instance, if your low back pain is coming from the facet joints — small joints deep in the spine, under a thick layer of muscle — chances are that a topical treatment simply doesn’t stand a chance of having an effect.
Pycnogenol, like white willow bark, is a nutraceutical material that has been used since ancient times. Pycnogenol is derived from the bark of the maritime pine tree (Pinus maritima) and has been used for more than 2000 years. It has been considered helpful for wound healing, treating scurvy, healing of ulcers, and reducing vascular inflammation. It contains a potent blend of active polyphenols, which includes catechin, taxifolin, procyanidins, and phenolic acids. It is one of the most potent antioxidant compounds currently known.[17,118]
Over-the-counter (OTC) pain relievers. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve), might relieve acute back pain. Take these medications only as directed by your doctor. Overuse can cause serious side effects. If OTC pain relievers don't relieve your pain, your doctor might suggest prescription NSAIDs.

We looked at both gels and creams to create our top ten list. How did we evaluate consistency? We looked at whether the substances stained, went on greasy, or were otherwise messy to deal with. Did users like the feel of the gel or cream on their skin? Why or why not? We also looked at whether formulas were quick drying and whether they left a residue. When it came to ingredients, we wanted to select as many options as possible with natural ingredients that were easily recognizable.
The Penetrex® pain relief cream is a top choice for those suffering from arthritis, back pain, fibromyalgia, neck pain, sciatica, carpal tunnel syndrome, sore aching joints and muscles, tennis and golfer’s elbow, neuropathy, sports injuries, plantar fasciitis, strains, sprains, hip and shoulder pain, all pain and other inflammations. The advanced development cream comes in a 2-ounce jar with other sizes available. Eight years went into the development and creation of this fantastic cream. Penetrex is favored by people troubled with inflammation related injuries because it works!
Still an excellent product. It remains effective for pain relief for about 5 hours with each application for me. Make sure to rub in a good thick portion for several minutes to the entire area of pain. Each jar of Synthaflex lasts about 18 days for me with applications twice each day. It remains the best external joint and muscle pain relief rub that I have ever used.
A key warning about using topical analgesics: don’t use them if you are also taking an oral NSAID—either prescription or over-the-counter—without telling your doctor. Taking too much of an NSAID can land you in the hospital with stomach bleeding or an ulcer flare-up. In fact, up to 100,000 Americans are hospitalized every year for NSAID-related gastrointestinal problems.
One of the most common reasons people develop low back pain is posture. Postural problems, including spinal abnormalities, along with muscular compensations or inactivity put added pressure on the back. Although people of all ages experience low back pain — including both athletes and those who are sedentary — middle-aged to older adults (especially when they’re overweight) are most likely to develop severe symptoms and therefore can benefit from lower back pain relief treatments like chiropractic care, soft tissue therapy and regular exercise.
If you think you may have a medical emergency, call your healthcare provider or 911 immediately. Any mention of products or services is not meant as a guarantee, endorsement, or recommendation of the products, services, or companies. Reliance on any information provided is solely at your own risk. Please discuss any options with your healthcare provider.
Consumer Reports is an independent, non-profit organization dedicated to helping consumers. We make it easy to buy the right product from a variety of retailers. Clicking a retailer link will take you to that retailer’s website to shop. When you shop through retailer links on our site, we may earn an affiliate commission – 100% of the fees we collect are used to support our mission. Learn more. Our service is unbiased: retailers can’t influence placement. All prices are subject to change.

For those amenable joints, though, Voltaren® Gel delivers a good dose of medication directly to the joint, while sparing the gastrointestinal tract from the harshness of NSAIDs — which are actually known as “gut burners,” and many people just can’t stomach ibuprofen. A gel almost completely eliminates the risks associated with digesting the stuff.4
Curcumin is a naturally occurring yellow pigment derived from turmeric (Curcuma longa), a flowering plant of the ginger family. It has traditionally been used as a coloring and flavoring spice in food products. Curcumin has long been used in both Ayurvedic and Chinese medicines as an anti-inflammatory agent, a treatment for digestive disorders, and to enhance wound healing. Several clinical trials have demonstrated curcumin’s antioxidant, anti-inflammatory, and antineoplastic effects. Results of a study by Zandi and Karin suggested that curcumin might be efficacious in the treatment of cystic fibrosis because of its anti-inflammatory effect.[121] Curcumin is known to inhibit inflammation by suppressing NF-kB, restricting various activators of NF-kB as well as stemming its expression.
We looked at both gels and creams to create our top ten list. How did we evaluate consistency? We looked at whether the substances stained, went on greasy, or were otherwise messy to deal with. Did users like the feel of the gel or cream on their skin? Why or why not? We also looked at whether formulas were quick drying and whether they left a residue. When it came to ingredients, we wanted to select as many options as possible with natural ingredients that were easily recognizable.
The contents displayed within this public group(s), such as text, graphics, and other material ("Content") are intended for educational purposes only. The Content is not intended to substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your healthcare provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in a public group(s).

While leading the most vigorous life filled with project deadlines and domestic responsibilities and accomplishing success at all endeavors do you sometimes get compelled to lag behind other such active individuals given to the muscle pain agony? And does this dilemma affect you at a most recurring frequency at times when you are preparing for an office presentation or venturing out to complete household tasks? Be aware that in order to prevail as a most efficient professional and sincere family person putting forward causes of back pain or calf cramp or wrist soreness as reasons for not fulfilling your duties is the least enterprise that you can undertake.
Think of Voltaren® Gel as “ibuprofen in a gel.” (It’s actually diclofenac, but ibuprofen is a much more familiar drug name in North America, where the product is still fairly new, and available only with a prescription in the US.) It’s a topical anti-inflammatory medication,NSAID“Non-steroidal anti-inflammatory drug,” usually pronounced “en-sed.” and FDA-approved to treat osteoarthritis in “joints amenable to topical treatment, such as the knees and those of the hands.” The evidence shows that it “provides clinically meaningful analgesia.”1 This is an appealing treatment idea that actually works reasonably well: what a pleasure to be able to say that!2
Ensure that the type of anti-inflammatory cream you buy for yourself, a friend, or family member is of the right quality and more efficient in helping you deal with your health predicaments. The best quality brands would be fast acting and gentle to your skin with every application. Most of all, the cream that you choose at any given point in time should not have any side effects otherwise you would be exposing yourself to the ordeal of tackling what would result from using the poor quality creams in hopes of dealing with a minor injury. The best cream would take the shortest period to help relieve you of any kind of pain or inflammation so that you would comfortably carry on with whatever you might be doing.
Hi Shelie, Sorry to hear about your fracture. Comfrey cream is traditionally used to boost healing and is known as ‘knitbone’. It contains allantoin – a substance which is also beneficial for Raynaud’s. As described in my post, a trial showed rapid reduction in pain, and more effectiveness than for diclofenac gel in reducing symptoms associated with ankle sprain. A cream will sink in better than an ointment if you are working as a seamstress. Best wishes, Sarah B
Many readers assume that “skeptics” will always favour mainstream and pharmaceutical treatments like Voltaren, but nothing could be further from the truth. Indeed, some skeptics are leading the charge against bad pharmaceutical industry science and practices (and a great example is Ben Goldacre’s new book, Bad Pharma: How drug companies mislead doctors and harm patients). Pharmacist Scott Gavura of Science-Based Pharmacy was certainly skeptical about topical NSAIDs like Voltaren when he first tackled the topic early in 2011.13 “When I recently noticed a topical NSAID appear for sale as an over-the-counter treatment for muscle aches and pains … I was confident it would make a good case study in bad science.”
"Arnicare Gel ($8; target.com) had me at first application. It not only works great to help relieve any muscle pain and swelling, but it also has no scent and isn't greasy. I can apply it at night or even before a workout." —Derek DeGrazio, celebrity trainer, Barry's Bootcamp Miami Beach (See his Barry's Bootcamp-Inspired Abs, Butt, and Core Workout.)

I will admit I wasn't a believer. I have torn my knees all up and have had surgery. Surgery fixed the torn meniscus but the pain didn't stop. So I got on the pain pill routine. I hate taking the pills they make me feel fuzzy. A friend recommended Topricin to me. I got some and used it. Within days I noticed I needed less pills. It really does help the pain. I love it IT WORKS! I still have the pills in case it gets really bad but most of the time the pain can be managed by using the cream. I even keep a small tube in my purse just in case I need it. It also helps to show people what I am using. An added benefit is that it doesn't smell.
Hi iv just had my cast removed following my broken wrist where both bones were broken, im 58 and would like advice on which creams/gels i could safely use to help reduce the swelling in my fingers and hand and help reduce the muscle and tendon stiffness, im already doing exercises but the swelling stops me from being able to do much, im a self employed seamstress so maximising the use of my hand is essential, i cant use ice packs as i have Raynards syndrome, any advice would be very much appreciated, kindest regards
Reduce the inflammation that's contributing to your pain. It may seem obvious but it bears repeating; inflammation is a contributor to most forms of chronic pain, and reducing the inflammation will help reduce your pain. A simple way to address inflammation is to regularly apply a cold pack or ice to the local area of pain. Ice also helps by acting as a local anesthetic and by slowing nerve impulses, which in turn can interrupts the pain signals generated in the affected area.
Health.com is part of the Meredith Health Group. All rights reserved. The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments. All products and services featured are selected by our editors. Health.com may receive compensation for some links to products and services on this website. Offers may be subject to change without notice. See the Terms of Servicethis link opens in a new tab and Privacy Policythis link opens in a new tab (Your California Rightsthis link opens in a new tab)for more information. Ad Choicesthis link opens in a new tab | EU Data Subject Requeststhis link opens in a new tab
MSM is a potent sulfur naturally found in plants, animals and humans that helps rebuild the connective tissue in your joints and is a powerful natural remedy for inflammation and pain. What’s more, MSM has the unique ability to improve cell permeability. This allows harmful toxins to flow out, while allowing health boosting nutrients to flow in to feed your joints, cartilage and connective tissue. It is used for hundreds of symptoms related to a myriad of health diseases and conditions, and is especially effective as a natural remedy for relieving inflammation for improved joint function, and pain associated with joint inflammation, osteoarthritis, rheumatoid arthritis, osteoporosis and tendonitis. One study published in the Journal of AntiAging Medicine found that MSM provides an 80 percent greater reduction in pain compared to the placebo.
You should always consult with a medical professional to get a diagnosis and consultant about treatments, but if they suggest an OTC cream as part of your treatment, there are some good ones to consider. You can find creams with various ingredients and in a variety of formats, including gels, roll-ons, and lotions. Some have a cooling effect, while others bring the heat, and there are scented and unscented options, so it all comes down to preference.
One of the products I like mixes bromelain, curcumin, and quercetin. This powerful trio provides enhanced support for maintaining a healthy inflammatory response to reduce pain. Another favorite is a blend that contains essential nutrients the body needs to repair and recover, along with potent herbal pain alleviators, including black cohosh, white willow bark, valerian, and devil’s claw. Lastly, I suggest a high-potency proteolytic enzyme product combined with rutin. This supports the body’s natural processes for tissue and joint recovery. The enzymes work synergistically with rutin to naturally boost muscle and tissue repair.
×