In summer 2018 I had my first personal experience with dramatic relief from Voltaren Gel (topical diclofenac). It’s not the first time I have found it useful, but it was the first time it was amazing. I’d been having some unexplained knee pain intermittently for several weeks when it kicked up a notch or two and became constant and even started waking me up at night. When I finally remembered to try Voltaren Gel — I’m not sure what took me so long — things were bad enough that it was going to be obvious if it worked. And it was! After many days of constant discomfort ranging from 3-6 on a 10-scale, it just ended: half an hour after applying the stuff, I simply didn’t have that problem anymore. Hallelujah! It’s been weeks since then with no relapse. Although the pain was not terrible, this is actually one of the clearest examples of pain relief from any treatment that I’ve ever enjoyed.

There is plenty of pain relief cream out on the market. So it becomes quite challenging to choose the best one for reducing the severe pain you have. But we research a lot and make a list of top 10 best pain relief creams which works greatly to reducing the pain and gives you an extreme clam sensation. Let’s discuss the 10 best pain relief creams and their reviews below:


The good news is that myofascial release is also something we can do for ourselves! A recent study showed that a regular program of self-myofascial release lowered pain intensity and lessened stiffness. To start, you can simply lie on the floor and place a small, soft ball (around the size and density of a large orange) under any tight and painful muscle areas. Then allow your body to sink onto and around the ball for a few minutes to provide the right amount of sustained pressure to allow the fascia to release. Learn how to self-myofascial release with this Myofascial Self Care Video Course that was developed by a pair of myofascial release therapists, and is is a great way to do MFR treatment at home.
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Creams derived from natural products can also provide local relief for painful muscles in fibromyalgia. The best part is that topical treatments tend to be very well tolerated with few side effects. Arnica is an herb used since the 1500s to treat bruises, muscle pain, and inflammation. It is still used today as a natural treatment for muscle pain in many different topical remedies. One herbal homeopathic cream that I have found helpful is MyPainAway Fibro cream. It includes arnica to reduce muscle pain, echinacea to reduce inflammation, along with other herbs targeted to reduce nerve pain by improving microcirculation around pain-sensing nerves.
The powerful anti-inflammatory ginger is more effective than drugs like ibuprofen for pain relief, according to a 2013 study published in the journal Arthritis. The study revealed that drugs like Tylenol or Advil do block the formation of inflammatory compounds. Ginger, however, “blocks the formation of the inflammatory compounds–prostaglandins and leukotrienes–and also has antioxidant effects that break down existing inflammation and acidity in the fluid within the joints,” reported care2.com.
Could you find pain relief through a method that focuses on soft tissue manipulation and your psyche? The answer is yes. Rolfing, also known as structural integration, involves soft tissue work and movement education to realign your body’s myofascial structure with gravity. (8) (Think of your body’s fascia as the “netting” that encases your muscles and organs.)

I use my Rogue Fitness Supernova ($40; roguefitness.com) for self-myofascial release (SMR). By applying pressure directly to sore muscles with my supernova, I am able to roll out knots (or adhesions) on the muscle. This allows the body to bring blood flow to troubled areas by transporting nutrients and oxygen to the muscles for faster repair." — Troy Brooks, YG Studios and founder TB Elite Fitness


While most people are only looking to relieve the immediate symptoms of the pain, this will only provide temporary relief.  Addressing the underlying mental/emotional, chemical and physical stressors that are causing the chronic inflammation and pain is the ultimate goal.  This process takes time and deep introspection along with trusted holistic health care providers.

Most of these gels and creams won’t cure your ailment. You’ll probably run into countless negative reviews of products from people that complain that their pain is not gone. These types of products are not a cure. Pain relief creams and gels are a helpful way to reduce pain. With acute pain, these gels and creams help users get relief until treatment can occur. In the case of a sprained ankle or torn muscle, for instance, using this kind of medicine can be a good alternative to NSAIDs to help reduce pain. For chronic ailments like arthritis, these substances are merely a way to help sufferers cope with pain. They are a band-aid. Some aches and pains may be helped with further treatment but don’t expect miracles with these types of products. Just because they don’t completely remove pain doesn’t mean they aren’t helpful in some instances and for some people.
Diclofenac topical gel (Voltaren) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the lining of the joints) in certain joints such as those of the knees, ankles, feet, elbows, wrists, and hands. Diclofenac topical liquid (Pennsaid) is used to relieve osteoarthritis pain in the knees. Diclofenac is in a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by stopping the body's production of a substance that causes pain.
“I recently started using Relief in my practice after being introduced to the product by a friend. My patients tell me they prefer Relief to the other analgesic gel because Relief works better, lasts longer, and there is no stickiness or unpleasant scent after using the cream. In addition to the patient response, I use Relief in my office because Corganics provides a high quality product with great customer service. Relief has been a great addition to my practice.” *
For those sore muscles and inflammation, peppermint oil and pine will relieve your aches and the chamomile and eucalyptus relieve tender feeling pain. For relieving the stress you are feeling, pink grapefruit, lemongrass, and spearmint oil will do that for you. These are all natural products providing you with vitamins A and C and antioxidants with the aloe vera providing moisture to your skin.
Keep moving. "Our spines are like the rest of our body -- they're meant to move," says Reicherter. Keep doing your daily activities. Make the beds, go to work, walk the dog. Once you're feeling better, regular aerobic exercises like swimming, bicycling, and walking can keep you -- and your back -- more mobile. Just don't overdo it. There's no need to run a marathon when your back is sore.
“I was first introduced to Relief by my Chiropractor after I pulled a muscle. Later my son, while playing hockey, received a very nasty hit during a game and was given Biofreeze as part of his recovery process. I can tell you Relief is 10x better—he was still in pain after using the Biofreeze, so I grabbed the Relief and he could not believe the difference. Now we are a Relief ONLY household. I am spreading the word to all the other hockey mom’s on the quality of your product and how well it works. Thank you for creating Relief and keep up the good work.” *
Last year, I suffered a severe attack of gouty arthritis. I was crying in pain and tried several pain killers without any effect. Then, I consulted my doctor. He told me to not take any pain killers and prescribed Generic Colchicine 0.5mg no rx instead. And thankfully, the pain started subsiding. I would like to recommend this medicine to all patients suffering from gouty arthritis.
Deng ZH, Zeng C, Yang Y, et al. Topical diclofenac therapy for osteoarthritis: a meta-analysis of randomized controlled trials. Clin Rheumatol. 2016 May;35(5):1253–61. PubMed #26242469. “Topical diclofenac is effective in pain relief as a treatment of OA. It may also have a potential effect in function improvement, which needs further studies to be explored. Although, some adverse effects were observed in the application of topical diclofenac, none of them was serious.” BACK TO TEXT
Magnesium is the fourth most abundant mineral in the body. Involved in over 300 biochemical reactions, it helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and preserves bones strength. Magnesium also helps regulate blood sugar levels, promotes normal blood pressure, and is known to be involved in energy metabolism and protein synthesis.
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.
Arnica is a natural anti-inflammatory, which is why you’ll find it in many pain relief gels and creams. It is a powerful natural medicine that comes from the perennial flower Arnica Montana. It that makes natural quick and easy pain relief possible, and it is also one of the biggest reasons why most pain relief gels and creams that use Arnica are available over the counter without a prescription or a doctor’s visit.

Jackson, M., & Tummon Simmons, L. (2018, April 1). Challenging case in clinical practice: Improvement in chronic osteoarthritis pain with use of arnica oil massage, therapeutic ultrasound, and acupuncture — A case report [Abstract]. Alternative and Complementary Therapies, 24(2), 60–62. Retrieved from https://www.liebertpub.com/doi/abs/10.1089/act.2018.29152.mja?journalCode=act
Having a variety of solutions for pain relief is not only helpful, it’s strategic. Depending on which type of pain you’re experiencing, you want a personalized option. And having different solutions on hand helps you be prepared for whatever life throws at you. Try adding an external pain relief cream to the mix so you can relieve muscle and joint pain, then get back to doing what you love.

Sometimes referred to as vitamin P, citrus bioflavonoids enhance the absorption of vitamin C and act as important antioxidants. Flavonoids also inhibit collagenase and elastase, the enzymes responsible for the breakdown of connective tissue. Connective tissue breakdown is one of the factors that may cause arthritis. Flavonoids reinforce the natural structure of collagen, improve the integrity of connective tissue, protect against free radical damage and are a great natural remedy for inflammation and pain.
You should always consult with a medical professional to get a diagnosis and consultant about treatments, but if they suggest an OTC cream as part of your treatment, there are some good ones to consider. You can find creams with various ingredients and in a variety of formats, including gels, roll-ons, and lotions. Some have a cooling effect, while others bring the heat, and there are scented and unscented options, so it all comes down to preference.
Schematic showing another inflammatory pathway that is activated by tissue injury. This is the NF-kB activation, in which once the protein is free as a result of tissue injury, it can enter the cell nucleus and activate the DNA to enhance the inflammatory response further by the production of additional cytokines, chemokines, and adhesion molecules (IKKB = IkB kinase)

I will admit I wasn't a believer. I have torn my knees all up and have had surgery. Surgery fixed the torn meniscus but the pain didn't stop. So I got on the pain pill routine. I hate taking the pills they make me feel fuzzy. A friend recommended Topricin to me. I got some and used it. Within days I noticed I needed less pills. It really does help the pain. I love it IT WORKS! I still have the pills in case it gets really bad but most of the time the pain can be managed by using the cream. I even keep a small tube in my purse just in case I need it. It also helps to show people what I am using. An added benefit is that it doesn't smell.
Stay strong. Once your low back pain has receded, you can help avert future episodes of back pain by working the muscles that support your lower back, including the back extensor muscles. "They help you maintain the proper posture and alignment of your spine," Reicherter says. Having strong hip, pelvic, and abdominal muscles also gives you more back support. Avoid abdominal crunches, because they can actually put more strain on your back.
Customers say that while they were skeptical at first, they are pleasantly surprised by just how well this lotion from Two Old Goats works to relieve arthritis pain. Its name come from its key ingredient—goat’s milk—which is blended with essential oils, including lavender, rosemary, peppermint, and eucalyptus in a formula designed to penetrate deep into your joints and muscles. All those oils also act as a moisturizer so it keeps your skin looking great too, and the pump bottle makes it easy to dispense.
I am a science writer, former massage therapist, and I was the assistant editor at ScienceBasedMedicine.org for several years. I have had my share of injuries and pain challenges as a runner and ultimate player. My wife and I live in downtown Vancouver, Canada. See my full bio and qualifications, or my blog, Writerly. You might run into me on Facebook or Twitter.
What makes a joint “amenable”? Is it mellow and easy-going? No, just accessible: a pain-killing gel is useful only for joints that aren’t covered by a thick layer of muscle (like the shoulder). The medication gets diluted as it penetrates deeper into tissue, and a meaningful amount can only get into joints if the joint is just under the surface of the skin.
In as much as your doctor would prescribe these types of medication for you, whenever you shop for an Over The Counter cream such as the ones outlined above you would be left with minimal choice to make aside from the fact that you would be required to make comparisons based on the price of the product, its brand and the types of ingredients used in formulating the cream. These types of cream would play a very significant role in enabling you to effectively deal with cases of bruises, skin inflammation as well as muscle and joint pains. The most effective anti-inflammatory cream qualities are the ones that would be readily absorbed into the skin for enhanced action. The cream can be your best friend if it happens that you may be unwilling to take pills. Besides, most of these creams do not have side effects as long as they are used as instructed.

Think of Voltaren® Gel as “ibuprofen in a gel.” (It’s actually diclofenac, but ibuprofen is a much more familiar drug name in North America, where the product is still fairly new, and available only with a prescription in the US.) It’s a topical anti-inflammatory medication,NSAID“Non-steroidal anti-inflammatory drug,” usually pronounced “en-sed.” and FDA-approved to treat osteoarthritis in “joints amenable to topical treatment, such as the knees and those of the hands.” The evidence shows that it “provides clinically meaningful analgesia.”1 This is an appealing treatment idea that actually works reasonably well: what a pleasure to be able to say that!2

How it works: A misaligned spine can cause muscle tension (read: pain). Both physical therapy and chiropractic treatment improve spinal alignment. Physical therapists strategically stretch and strengthen the muscles that help hold the spine in place. Chiropractors manipulate the spine to relieve areas of tension on the muscles. Consult your primary-care doctor for a referral.
Voltaren® Gel (topical diclofenac) is a particularly safe and useful medicine. It’s an anti-inflammatory cream, so it can be applied only where you need it, instead of soaking your entire system with a medication, avoiding or dramatically reducing common side effects like indigestion, as well as some serious safety concerns associated with oral diclofenac. In the US, this drug is FDA-approved to treat osteoarthritis in “joints amenable to topical treatment, such as the knees and those of the hands,” but it probably also works for some other painful problems, such as some repetitive strain injuries and back pain. The evidence shows that it “provides clinically meaningful analgesia.” So this product actually works and gets a pass from skeptics and critics — a rare thing in the world of pain treatments!
Stretch. Don't sit slumped in your desk chair all day. Get up every 20 minutes or so and stretch the other way. "Because most of us spend a lot of time bending forward in our jobs, it's important to stand up and stretch backward throughout the day," Reicherter says. Don't forget to also stretch your legs. Some people find relief from their back pain by doing a regular stretching routine, like yoga.
With more than 23,000 reviews on Amazon, customers give Penetrex sky-high marks for effective pain relief. If it doesn’t work for you, it comes with a 100 percent, no-questions-asked, money-back guarantee. Formulated to fight inflammation, it contains a mix of ingredients including arnica, choline, glucosamine, Vitamin B6, and MSM. It’s not odor-free, but rather has a light scent that disappears quickly after you apply it. You can use it alone or in conjunction with heating pads, massagers, ice, and other therapies.

The evaluation of nutraceutical preparations with appropriately designed controlled studies has exploded in recent years. There is now a greater degree of confidence based on controlled study design and improved quality of the investigators that has strengthened positive findings found using natural compounds to treat diseases. It is important for healthcare practitioners to learn about these scientific studies to counsel patients who are taking various dietary supplements, herbs minerals and vitamins for both disease treatment and prevention.


The evaluation of nutraceutical preparations with appropriately designed controlled studies has exploded in recent years. There is now a greater degree of confidence based on controlled study design and improved quality of the investigators that has strengthened positive findings found using natural compounds to treat diseases. It is important for healthcare practitioners to learn about these scientific studies to counsel patients who are taking various dietary supplements, herbs minerals and vitamins for both disease treatment and prevention.
Could you find pain relief through a method that focuses on soft tissue manipulation and your psyche? The answer is yes. Rolfing, also known as structural integration, involves soft tissue work and movement education to realign your body’s myofascial structure with gravity. (8) (Think of your body’s fascia as the “netting” that encases your muscles and organs.)
If your back pain hasn't resolved itself within four to six weeks, you'll want to make an appointment with your doctor. Your doc will examine your back and ask you to sit, stand, bend, walk, and lift your legs to see how your pain is affecting your mobility. You'll likely be asked to rate your pain on a scale of one to 10, and you may be sent for imaging tests like an x-ray or MRI. You might be asked to try one of these therapies:
Aloe barbadensis (organic aloe) leaf juice, Limnanthes alba (meadow foam) seed oil, mentha arvensis (menthol), capsicum (capsicum annuum) oleoresin, cinnamomum camphora (white camphor) essential oil, ocimum basilicum (sweet basil) essential oil, piper nigrum (black pepper) essential oil, anthemis nobilis (Roman chamomile) flower essential oil, chamomilla recutita (German chamomile) flower essential oil, cinnamomum zeylanicum (cinnamon) leaf essential oil, cymbopogon winterianus (citronella) essential oil, eucalyptus globulus (eucalyptus) leaf essential oil, helichrysum italicum (helichrysum) essential oil, zingiber officinale (ginger) root essential oil, citrus paradisi (pink grapefruit) essential oil, juniper communis (juniper) berry essential oil, cymbopogon flexuous (lemongrass) essential oil, mentha piperita (peppermint) essential oil, pinus sylvestris (pine) needle essential oil, ravensara aromatica (ravensara) essential oil, Rosmarinus officinalis (rosemary) leaf essential oil, mentha spicata (spearmint) essential oil, origanum vulgare (wild oregano) essential oil, glycerin, hamamelis virginiana (witch hazel), water, alcohol, phenoxyethanol, carbomertriethanolamine (TEA), and tetrasodium (EDTA)
Herbal therapies: “When back spasms are so strong you can barely move from the bed,” Grossman says, she suggests the homeopathic medicine Bryonia; when you have soreness after overexertion, she uses Arnica.  Keep in mind, there’s little scientific evidence that herbals such as Bryonia and Arnica are effective treatments for back pain; though, a study published in Alternative Therapies in Health and Medicine in 2016 suggested they might help to reduce chronic low back pain from arthritis when combined with physical therapy.
Sudden and intense cold exposure makes you release cold-shock proteins, a special class of proteins that decrease inflammation and speed up recovery.[10] To get the benefits of cold therapy, you can take an ice bath or use a cryotherapy chamber, like the one at Bulletproof Labs. Cryotherapy’s benefits go far beyond inflammation, too. Get a full breakdown of how cryotherapy upgrades your biology.
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