The human body’s natural response to injury results in inflammation-induced pain, swelling, and erythema. In order to reduce pain, anti-inflammatory agents such as NSAIDs act on the multiple inflammatory pathways, which, although often very effective, can have undesirable side effects such as gastric ulceration and, infrequently, myocardial infarction and stroke.
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Think of Voltaren® Gel as “ibuprofen in a gel.” (It’s actually diclofenac, but ibuprofen is a much more familiar drug name in North America, where the product is still fairly new, and available only with a prescription in the US.) It’s a topical anti-inflammatory medication,NSAID“Non-steroidal anti-inflammatory drug,” usually pronounced “en-sed.” and FDA-approved to treat osteoarthritis in “joints amenable to topical treatment, such as the knees and those of the hands.” The evidence shows that it “provides clinically meaningful analgesia.”1 This is an appealing treatment idea that actually works reasonably well: what a pleasure to be able to say that!2
Turmeric can be consumed in a variety of forms, including as a spice added to foods or drinks and encapsulated for those who are not tolerant of the signature spicy taste. Two to three teaspoons of turmeric daily can help to provide therapeutic levels of relief and preventive benefits with little side effects. Note: Turmeric absorbs best when taken in combination with black pepper (approximately 1/4 teaspoon of black pepper for every 1 teaspoon of turmeric). (17)
This can vary depending on the reason for treating you, so speak with your doctor for advice. If you are using an anti-inflammatory for acute muscle pain, usually treatment lasts for as long as you have pain and inflammation. For example, a few days, or weeks. But if you are being treated for conditions like osteoarthritis, your doctor may advise you to use this medicine for the long term.
Boswellia serrata is a traditional Indian Ayurvedic remedy for inflammatory conditions. It is extracted from the gum of the Indian boswellia tree and has been in use for centuries to treat joint pain and inflammation. It provides anti-inflammatory activity in areas where there is chronic inflammation by turning off the pro-inflammatory cytokines that begin the inflammatory process. Moreover, research shows that the acids contained within boswellia extract stop the formation of immune cells known as leukotrienes, which are responsible for inflammation. This then allows blood to flow unobstructed to the joints for healing and improved mobility.

Dr. Pergolizzi venture offers this exquisite sore muscle cream that is scientifically proven to be about 2X effective over aches and arthritis dilemma than its competitors at a most fast pace. The foremost pain relief cream reviews primarily upheld it for the Oxygenated Oil and Menthol nurtured composition, which provides an enduring and cool comfort over all sorts of muscle pulls and swellings. The sore muscle cream owns a Zero Stinking texture and is also effective to eradicate the issue of vein throbbing. The pain relief cream reviews also favor it for its functionality to make stiffened muscles relax and treat even bursitis sting. The ‘Oxy Rub’ salve is available in both 2oz and 4oz tubes.
The active ingredients in fish oil, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), enhance the conversion of COX to prostaglandin E3. A natural anti-inflammatory agent, prostaglandin E3 competitively inhibits the effects of the arachidonic acid conversion to prostaglandin E2, a highly inflammatory substance. Prostaglandin E3 also inhibits the synthesis of TNF-α and IL-1b, both of which are inflammatory cytokines. The EPA and DHA can inhibit the 5-LOX pathway, which converts arachidonic acid to inflammatory leukotrienes, by competitive inhibition as well. When EPA and DHA are incorporated into articular cartridge chondrocyte cell membranes, there is a dose-dependent decrease in the expression and activity of the proteoglycan-degrading aggrecanase enzymes.[12,23–25,27,50,85]
These creams can be quite effective for temporary pain relief on the muscle and joints. The creams would also come in handy when handling inflammations that may be brought forth by minor injuries, sunburn, skin rash and other severe conditions. Although doctors would prescribe most of these creams for their patients, more often than not individuals go for the OTC medications to deal with simple medical conditions. When making your purchase for this particular product it is important that you make a comparison between active ingredients and the inactive ingredients used in the formulation of the cream. At the end of the day, ensure that you choose a product that would not have dire side effects on your health. The cream you choose should help you deal with your particular problem in the best way possible and if possible you should make sure that you consult with your doctor before using any of these creams.
Cognitive Behavioral Therapy (CBT). In CBT, a psychotherapist helps you identify problematic behaviors (like becoming less active or doing fewer fun activities in response to pain), negative thoughts (about self, others and the future) and feelings (depression, guilt, anxiety). This can increase your awareness of how problematic patterns develop and help you understand the connection between thought patterns and feelings. You are then trained in pain coping skills, such as relaxation techniques, imagery, and goal setting, encouraging you to have an active role in managing and controlling pain. CBT can increase your ability to control pain while acknowledging that there may be occasionally flares beyond your control.
If you need stronger pain relief, talk to your doctor about a prescription topical NSAID. A prescription topical NSAID is stronger than OTC products. Topical NSAIDs also carry less risk of stomach upset, ulcers, or other problems than oral NSAIDs do. The only prescription topical NSAID currently available is called Voltaren (diclofenac). Talk to your doctor to find out if it’s right for you.

Aloe barbadensis (organic aloe) leaf juice, Limnanthes alba (meadow foam) seed oil, mentha arvensis (menthol), capsicum (capsicum annuum) oleoresin, cinnamomum camphora (white camphor) essential oil, ocimum basilicum (sweet basil) essential oil, piper nigrum (black pepper) essential oil, anthemis nobilis (Roman chamomile) flower essential oil, chamomilla recutita (German chamomile) flower essential oil, cinnamomum zeylanicum (cinnamon) leaf essential oil, cymbopogon winterianus (citronella) essential oil, eucalyptus globulus (eucalyptus) leaf essential oil, helichrysum italicum (helichrysum) essential oil, zingiber officinale (ginger) root essential oil, citrus paradisi (pink grapefruit) essential oil, juniper communis (juniper) berry essential oil, cymbopogon flexuous (lemongrass) essential oil, mentha piperita (peppermint) essential oil, pinus sylvestris (pine) needle essential oil, ravensara aromatica (ravensara) essential oil, Rosmarinus officinalis (rosemary) leaf essential oil, mentha spicata (spearmint) essential oil, origanum vulgare (wild oregano) essential oil, glycerin, hamamelis virginiana (witch hazel), water, alcohol, phenoxyethanol, carbomertriethanolamine (TEA), and tetrasodium (EDTA)


To avoid unwanted weight gain, consuming inflammatory ingredients or complications due to nutrient deficiencies, reduce or eliminate the following foods: added sugar, sweetened beverages or snacks, refined vegetable oils, refined grain products, too much alcohol and tobacco products (smoking impairs blood flow and adds to nutrient deprivation to spinal tissues).

Zeng C, Wei J, Persson MS, et al. Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies. Br J Sports Med. 2018 Feb. PubMed #29436380. “Topical NSAIDs were effective and safe for OA. Diclofenac patches may be the most effective topical NSAID for pain relief. No serious gastrointestinal and renal AEs were observed in trials or the general population.” BACK TO TEXT


The powerful anti-inflammatory ginger is more effective than drugs like ibuprofen for pain relief, according to a 2013 study published in the journal Arthritis. The study revealed that drugs like Tylenol or Advil do block the formation of inflammatory compounds. Ginger, however, “blocks the formation of the inflammatory compounds–prostaglandins and leukotrienes–and also has antioxidant effects that break down existing inflammation and acidity in the fluid within the joints,” reported care2.com.

Whether the pain that someone experiences is activity related, leftover from an old injury, or due to a chronic inflammatory condition, bone broth in the diet can help to reduce chronic pain and flares. This is due to the presence of collagen in bone broth, which can help to alleviate joint problems and repair pain that originates from the digestive tract. (23)
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Warning: The gel is for external use only. It is flammable therefore keep it away from heat or open flames. Check with your healthcare provider before using it if you have sensitive skin are pregnant or breastfeeding. Do not put it near your eyes or mucous membranes or apply to wounds, sores, scratched or imperfect skin. Do not use this product with other creams, sprays, liniments, or ointments. Never put a bandage over the area. Stop using if your skin becomes red, has a rash, or feels irritated. Never use with a heating pad on top of the area and always wash your hands after using. Contact your doctor if problems continue after use. Consult your pediatrician if your child is under 2-years-old. Keep out of the reach of children.
Over-the-counter (OTC) pain medications are fairly safe and somewhat effective in moderation and work in different ways, so do experiment cautiously. There are four kinds: acetaminophen/paracetamol (Tylenol, Panadol), plus three non-steroidal anti-inflammatories (NSAIDs): aspirin (Bayer, Bufferin), ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn). Don’t take any of them chronically — risks go up over time, and they can even backfire and cause nasty rebound headaches. They are all probably equally effective for acute injuries (Hung), but benefits vary with people and issues (chronic pain, headache, arthritis, etc). Acetaminophen is good for both fever and pain, and is one of the safest of all drugs at recommended dosages, but it may not work well for musculoskeletal pain (at all?) and overdose can badly hurt livers. The NSAIDs all reduce inflammation as well as pain and fever, but at any dose they can cause heart attacks and strokes and they are “gut burners” (they irritate the GI tract, even taken with food). Aspirin may be best for joint and muscle pain, but it’s the most gut-burning of them all. Voltaren® Gel Review is an ointment NSAID, effective for superficial pain and safer (Derry). Athletes, puh-lease don’t take “Vitamin I” to prevent soreness — it doesn’t work!

7) The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma. Li M, Bolduc AR, Hoda MN, Gamble DN, Dolisca SB, Bolduc AK, Hoang K, Ashley C, McCall D, Rojiani AM, Maria BL, Rixe O, MacDonald TJ, Heeger PS, Mellor AL, Munn DH, Johnson TS. J Immunother Cancer. 2014 Jul 7; PMID: 25054064
“I was first introduced to Relief by my Chiropractor after I pulled a muscle. Later my son, while playing hockey, received a very nasty hit during a game and was given Biofreeze as part of his recovery process. I can tell you Relief is 10x better—he was still in pain after using the Biofreeze, so I grabbed the Relief and he could not believe the difference. Now we are a Relief ONLY household. I am spreading the word to all the other hockey mom’s on the quality of your product and how well it works. Thank you for creating Relief and keep up the good work.” *
Stretch. Don't sit slumped in your desk chair all day. Get up every 20 minutes or so and stretch the other way. "Because most of us spend a lot of time bending forward in our jobs, it's important to stand up and stretch backward throughout the day," Reicherter says. Don't forget to also stretch your legs. Some people find relief from their back pain by doing a regular stretching routine, like yoga.
Can stomach problems cause lower back pain? The back is a sensitive part of the body, which has many nerves and organs nearby. This means that issues such as digestive conditions can occur at the same time as back pain. Back pain and bloating are common symptoms of injury, pregnancy, or gastrointestinal problems. Treatment depends on the cause. Learn more here. Read now
For a blast of cool pain relief, Biofreeze has been a go-to for arthritis sufferers for decades. Made with 4 percent menthol, this gel promises immediate relief from pain that’s long-lasting. It has a light green color, so you can see where you’re applying it, but it also comes in a colorless version as well. Both versions are greaseless and have a scent that’s designed to disappear after application.

Having the best pain relief gel or cream in your household or any other place is a must. You can also keep this remedy in your office or in your purse as you don’t know when you have pain. Of course, suffering from a back pain is a one of the worst one. So you should always have a cream near you. Suppose due to work you get tired. You hit yourself somewhere and the entire day gets ruined. For this reason, you need to have a cream near to you as you can use it immediately and get relief from severe pain.
“I cannot even tell you how AMAZING this stuff is. I never do reviews, but this product most certainly deserves one. I have dealt with MANY injuries, I was in a bad car wreck, and I have had more surgeries than I could count on both hands. My main area of pain is my upper back and neck. I have bulging disks, cervical stenosis, degenerative disk disease that causes horrible spasms, swelling, tension, and PAIN. I also have cancer and several other issues that put my pain level over the top every day. I have seen neurosurgeons, all of whom say they will eventually need to operate. I have done absolutely every possible treatment other than a spinal fusion, have had probably 10 injections, and they even went and tried to burn the nerve endings throughout my entire cervical spine, yet nothing worked. I can't even begin to tell you the medications the doctors have tried, each of which help some, but you get to a point where you don't want to constantly take medications forever. One day I was at my spine doctor's office and they had a bottle of Relief pain cream on the counter. While I was waiting there I asked the staff some questions about Relief and thought "yea, yea, but can I try it?" So, I put some on, and thought, "HOLY COW! What is this! Whatever this is, it's amazing!" Then and there I literally bought the rest of the supply they had on-hand because I couldn't believe how much it helped relieve my pains and aches. That night, I couldn't sleep because I was in so much pain, and none of my medications were helping. I felt like I was dying. So again, I put on some Relief cream and it helped soooo much. Since that day I never, ever, go anywhere without Relief! I will use this pain cream forever and continue to tell everyone I know about it because it truly works! I'm so glad I randomly tried this stuff at the doctor's office because I finally found something that gives true RELIEF!!” *
"I have used your Arthritis Pain Relief Cream for a couple of years now, and I don’t know how I could do without it. I have arthritis in my back, arms, legs, and fingers. When I’m hurting, I apply the Cream, and the pain is gone in just a few minutes. I have referred this product to several friends and relatives. I also like your Intensive Night Repair Cream. I can’t live without it."

The use of both over-the-counter and prescription nonsteroidal medications is frequently recommended in a typical neurosurgical practice. But persistent long-term use safety concerns must be considered when prescribing these medications for chronic and degenerative pain conditions. This article is a literature review of the biochemical pathways of inflammatory pain, the potentially serious side effects of nonsteroidal drugs and commonly used and clinically studied natural alternative anti-inflammatory supplements. Although nonsteroidal medications can be effective, herbs and dietary supplements may offer a safer, and often an effective, alternative treatment for pain relief, especially for long-term use.


“I am a musician and have been one for almost 40 years. With practice and performance comes pain, which sometimes becomes chronic. I manage it with body work and adjustments but I can’t always be around practitioners, especially when I am traveling. These pain relieving patches fill the void extremely well providing relief, very quickly without chemicals or drugs. Kudos to Luminas for developing them. Highly recommended!” – Rafe S.
The omega-3 fatty acids found in abundance in fish oil derived from cod, trout, herring, salmon and other coldwater fish are proven natural remedies to reduce inflammation. Research from Cardiff University in Great Britain found that cod liver oil not only relieves pain, but also stops and even reverses the damage caused by osteoarthritis and rheumatoid arthritis. Omega-3s help morning stiffness, regenerate joint tissue and have been shown to also aid in autoimmune disease like RA, lupus and psoriasis.
Named for its hook-like horns, cat’s claw, a woody vine native to the Amazon rainforest and other places in South America, is known for containing an anti-inflammatory agent that aids in blocking the production of the hormone prostaglandin, which contributes to inflammation and pain within the body. Stick to the suggested doses to avoid diarrhea: 250 to 1,000 mg capsules one to three times daily.
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