People who used an ointment that contains this plant-based extract for 5 days reduced the intensity of lower back pain by 95%, according to a 2009 study conducted by Merck (which manufactures the ointment). In comparison, a placebo group had a 38% reduction in pain during that same time, according to the study in the British Journal of Sports Medicine. Look for comfrey root ointment in health food stores or online. Just don't use it for more than 10 days at a time—it can be toxic.
Topical ointments, such as sports and muscle creams, have been around for centuries.  After noticing their peculiar properties ancient civilizations began infusing plant ingredients into salves and ointments to help relieve pain.  Taking our inspiration from these time-tested traditions, Body Glide Relief was developed with a blend of menthol and methyl salicylate.  These plant derived ingredients combine to temporarily relieve muscle and joint pain.
NSAIDs such as topical diclofenac (Pennsaid, Voltaren) may cause swelling, ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who use NSAIDs for a long time, are older in age, have poor health, smoke, or drink alcohol while using topical diclofenac. Tell your doctor if you have any of these risk factors and if you have or have ever had ulcersor bleeding in your stomach or intestines, or other bleeding disorders. Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) or naproxen (Aleve, Naprosyn); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); or serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor XR). If you experience any of the following symptoms, stop using topical diclofenac and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool,or black and tarry stools.
The use of fish oil (in the form of cod liver oil), an omega-3 EFA, for the treatment of muscular, skeletal, and discogenic diseases, can be traced back to the late 18th century as detailed by Curtis et al.,[24,25] Unfortunately, because of the rapid onset of rancidity of this polyunsaturated oil when exposed to air, and hence its disconcerting odor, cod liver oil fell out of favor. With improved extraction techniques, such as using a protective nitrogen blanket and enhanced oxygen-free encapsulation methods, there is less chance of oxidation during the manufacturing process. The therapeutic benefits of fish oil can now be realized without the regurgitation and odor of previous products caused by peroxides and rancid tasting fish oil.[14]
“For most people, it means their back hurts,” says Richard A. Deyo, MD, MPH,the Kaiser-Permanente Endowed Professor of Evidence-Based Medicine in the department of family medicine at Oregon Health & Science University in Portland. “But it’s often impossible to know the precise anatomical cause of back pain because the back has so many sources of pain.”

Because natural supplements are made of organically existing substances, they affect the body in gentle ways—without side effects. The ingredients within natural remedies for inflammation, pain and anything for that matter often do not work as quickly as drugs do at relieving pain or inflammation. However, they do offer acute relief in the short term while working more powerfully over time to create a gradual and lasting change in condition. In other words, natural supplements need to build up in your system to get to a level where more significant change occurs, which is why you often will need to take them several times per day, over periods of weeks and months or even longer.

Nearly everyone suffers from some type of back pain at some point in their lives. But no matter when it appears or what may have caused it, back pain can be a real, well … pain to deal with. The good news? There are several simple things you can do to ease pain and keep your back in good condition. The following tips can help you get on the way toward feeling better.


Having a variety of solutions for pain relief is not only helpful, it’s strategic. Depending on which type of pain you’re experiencing, you want a personalized option. And having different solutions on hand helps you be prepared for whatever life throws at you. Try adding an external pain relief cream to the mix so you can relieve muscle and joint pain, then get back to doing what you love.
Pycnogenol, like white willow bark, is a nutraceutical material that has been used since ancient times. Pycnogenol is derived from the bark of the maritime pine tree (Pinus maritima) and has been used for more than 2000 years. It has been considered helpful for wound healing, treating scurvy, healing of ulcers, and reducing vascular inflammation. It contains a potent blend of active polyphenols, which includes catechin, taxifolin, procyanidins, and phenolic acids. It is one of the most potent antioxidant compounds currently known.[17,118]

Find support and understanding.. Unlike a broken leg or other obvious sign of injury, chronic pain is usually unseen. It is a profoundly personal—and often lonely—experience. For many, it is difficult to find support and understanding from family and friends who may be well intentioned but don't really get what you're dealing with. If this is the case for you, we encourage you to find your own group of people who can be supportive and understanding. There may be a chronic pain support group at your local hospital or church. Or you may prefer to interact online. You may get started with a local or online forum seeking help, and then go on to find that you have a lot to contribute, and helping others is also a way to help yourself.
I am a science writer, former massage therapist, and I was the assistant editor at ScienceBasedMedicine.org for several years. I have had my share of injuries and pain challenges as a runner and ultimate player. My wife and I live in downtown Vancouver, Canada. See my full bio and qualifications, or my blog, Writerly. You might run into me on Facebook or Twitter.

A key warning about using topical analgesics: don’t use them if you are also taking an oral NSAID—either prescription or over-the-counter—without telling your doctor. Taking too much of an NSAID can land you in the hospital with stomach bleeding or an ulcer flare-up. In fact, up to 100,000 Americans are hospitalized every year for NSAID-related gastrointestinal problems.

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

Release your inner endorphins. Endorphins are the natural pain relievers produced by your body. They work by binding to the opioid receptors in your brain to block the perception of pain, similar to opioid pain medications, such as oxycodone or morphine. Spurring increased production of these natural hormones can substantially help reduce your pain, as well as produce profound feelings of pleasure and satisfaction.1
In a 2011 research review published in the British Journal of Anaesthesia, investigators looked at the available research on the use of topically applied capsaicin in the treatment of several types of chronic pain. This included two clinical trials examining back pain, both of which found that capsaicin helped reduce low back pain without causing notable side effects.
This is a good option for anyone suffering from minor arthritis pain or sore muscles. It has no odor and is perfect for rubbing into the back to relieve backaches and pain. This product does not use any heating or cooling feature, so it is perfect for someone who wants a smell-free pain relief cream without a lot of added features. People have been using this cream for decades, and many continue to prefer it.
NSAIDs such as topical diclofenac (Pennsaid, Voltaren) may cause swelling, ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who use NSAIDs for a long time, are older in age, have poor health, smoke, or drink alcohol while using topical diclofenac. Tell your doctor if you have any of these risk factors and if you have or have ever had ulcersor bleeding in your stomach or intestines, or other bleeding disorders. Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) or naproxen (Aleve, Naprosyn); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); or serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor XR). If you experience any of the following symptoms, stop using topical diclofenac and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool,or black and tarry stools.
Rosenzweig, S., Greeson, J. M., Reibel, D. K., Green, J. S., Jasser, S. A., & Beasley, D. (2010, January). Mindfulness-based stress reduction for chronic pain conditions: Variation in treatment outcomes and role of home meditation practice. Journal of Psychosomatic Research, 68(1), 29–36. Retrieved from https://www.sciencedirect.com/science/article/pii/S0022399909000944
Get enough restorative sleep. Getting enough sleep is critical to managing pain and promoting healing, so it's important to employ a variety of sleep aids to help you get a healthy amount of sleep. Regular exercise that physically exhausts the body helps promote deep sleep. Visualization, meditation, and other psychological techniques can also help you get to sleep and stay asleep.
Acetylsalicylic acid works by irreversibly disabling the COX enzymes to block the cascade [Figure 1]. NSAIDs have evolved from blocking both COX-1 and COX-2 to selectively only blocking COX-2 in order to inhibit the inflammatory response and reduce the production of inflammatory prostaglandins and thromboxanes. The major push to develop the selective COX-2 inhibitors has been the recognition of significant complications associated with the nonselective COX-1 and COX-2 NSAIDs. Nonselective NSAIDs’ major side effects include significant gastrointestinal upset, gastritis, ulceration, hemorrhage, and even death. By locking COX-1, which also normally acts to protect the gastrointestinal mucosa, nonselective NSAIDs and aspirin can cause significant gastric tissue damage.[34,51,78,91,3,101,115]
SynthaFlex uses Celadrin®. Celadrin® is a patented matrix of cetylated fatty acid esters. It reduces inflammation to relieve joint pain and increase joint mobility. It also helps restore synovial fluid that cushions bones and joints to promote flexibility without pain. As a topical cream, it's design to be rapidly absorbed by the dermis to provide fast and continuous relief.
The use of both over-the-counter and prescription nonsteroidal medications is frequently recommended in a typical neurosurgical practice. But persistent long-term use safety concerns must be considered when prescribing these medications for chronic and degenerative pain conditions. This article is a literature review of the biochemical pathways of inflammatory pain, the potentially serious side effects of nonsteroidal drugs and commonly used and clinically studied natural alternative anti-inflammatory supplements. Although nonsteroidal medications can be effective, herbs and dietary supplements may offer a safer, and often an effective, alternative treatment for pain relief, especially for long-term use.
Cinnamon is a popular natural remedy for helping to control blood sugar, but it can also keep inflammation levels low in the body and improve digestion. (20) Spices have long been used for medicinal purposes, but in a modern day where pharmaceutical options abound, it is rarer to use food as medicine. Still, cinnamon and other spices can have broad anti-inflammatory benefits and in many cases, can be equally as effective to (or more) than NSAIDs, whether over-the-counter or prescription. (21)
My doctor reddened and paniced a bit when he took my B/P and blamed it on the tablets which I rarely took, but the gel had been increased due to a worsening scoliosis and and a damaged knee getting worse with age. Recent research states clearly that this is a serious side effect, and it was not just a small rise but one of 25-30 points on my normal B/P!!! It can also cause hardening of the arteries and eventually a heart attack.

Note: The cream is hot to your skin and should be used with caution. The heat comes from capsicum (capsicum annuum) oleoresin a hot pepper. Try a small amount the first time at your inside wrist and wait a half hour to see how it feels. Do not bathe or shower after putting it on because that will only make you feel hotter. Let your body cool down first. Never put the cream near your eyes or mucous membranes such at the lower nose. Do not use on your private area. Wash your hands after you have rubbed the cream into your skin.


Low and lower back pain can vary from dull pain that develops gradually to sudden, sharp or persistent pain felt below the waist. Unfortunately, almost everyone, at some point during life will experience low back pain that may travel downward into the buttocks and sometimes into one or both lower extremities. The most common cause is muscle strain often related to heavy physical labor, lifting or forceful movement, bending or twisting into awkward positions, or standing in one position too long.

Some manufacturers inflate nutraceutical products’ claims and may not cite possible side effects and potential drug interactions. Bleeding complications are associated with white willow bark, ginger, garlic, and others. Therefore, such medicinal preparations are not without risk. Products such as omega-3 essential fatty acids (EFAs) (O3) do have strong scientific support to be considered as an alternative and/or complementary agent to NSAIDs. Published studies have shown the effectiveness of O3 to successfully treat spine-related pain.[71] Capsaicin, oil of camphor, and other natural topical preparations are commonly used for muscle soreness and local application for painful traumatic injuries.[12,16,80] The subsequent sections will review many of these products and discuss both their efficacy and safety issues. As with any drug or natural compounds, additional caution should be used when considering these treatments for children, pregnant or lactating mothers or any other clinical or disease condition that could increase possible risk of side effect or complication.


8. Capsaicin (Capsicum) – Found in hot chile peppers, this natural remedy does wonders for pain. Capsaicin, the active pain-reducing ingredient, temporarily desensitizes nerve receptors called C-fibers which cause the pain response. Capsaicin also diminishes soreness for 3 to 5 weeks while the C-fibers regain sensation. A single 60-min application in patients with neuropathic pain produced effective pain relief for up to 12 weeks. Patients at the New England Center for Headache decreased their migraine and cluster headache intensity by applying capsaicin cream to their nasal passages.
ASU is a vegetable extract made from the oil of avocados and soybeans that is said to slow the progression of osteoarthritis. It slows down the production of inflammatory chemicals in the body and thus the breakdown of cartilage in the joints. It has also been found to spur new cartilage cell growth. It is available in capsule form at a recommended 300 mg daily.
If you need stronger pain relief, talk to your doctor about a prescription topical NSAID. A prescription topical NSAID is stronger than OTC products. Topical NSAIDs also carry less risk of stomach upset, ulcers, or other problems than oral NSAIDs do. The only prescription topical NSAID currently available is called Voltaren (diclofenac). Talk to your doctor to find out if it’s right for you.

Many pharmaceutical pain medications, while effective and useful at times, can be downright dangerous, but there is another solution to your pain problem. “Almost always, if we find pharmaceuticals doing the trick, we’ll find a plant doing the same trick—and doing it more safely,” remarks botanist James A. Duke, PhD, author of The Green Pharmacy Guide to Healing Foods.


The contents displayed within this public group(s), such as text, graphics, and other material ("Content") are intended for educational purposes only. The Content is not intended to substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your healthcare provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in a public group(s).
Research suggests that topical medications may be just as effective as oral ones. Many of them worked significantly better than placebo. These medications can come in the form of gels, creams, patches, and more. One study also saw decrease in pain when people applied lavender essential oil or ointments prepared with cayenne peppers with acupressure.
For arthritis relief, it is important to have proteolytic activity on the systemic level. Known as protease, this category of enzymes acts as a catalyst in the breakdown of proteins into peptides or amino acids. This helps control both systemic inflammation and inflammation resulting from soft tissue injuries, like those associated with both rheumatoid and osteoarthritis. Proteolytic enzymes also provide essential antioxidant and cardiovascular support. I will discuss two of the more potent ones here:
It’s estimated that up to 80 percent of adults experience persistent symptoms of lower back pain at some point in their lives, and about 31 million Americans struggle with the condition at any given time. Given its extremely high prevalence rate — whether due to a weak psoas muscle, sciatic nerve pain or some other cause — it’s not surprising that lower back pain is considered the single leading cause of disability worldwide according to the American Chiropractic Association, with half of all American workers reporting having occasional back troubles each year. (1) Naturally, this leads to millions searching for lower back pain relief.
Whether it was brought on by arthritis, a structural or nerve problem, bending the wrong way, or lifting something a little too heavy, low back pain is frustrating as all get-out. But if you're struggling, know this: You're definitely not alone. Most people experience back pain at some point in their lives, and it's one of the most common reasons people book doctor's appointments and call out of work. It's also one of the leading causes of disability worldwide.

The advantage of using a topical analgesic is that the medication works locally. Targeting pain more precisely using a medication applied to the skin can help skirt the side effects of oral drugs. This can be a boon for people whose stomachs are sensitive to NSAIDs. (Keep in mind that a small amount of the medicine still enters the bloodstream and ends up in the stomach and elsewhere, so a topical analgesic isn’t a guarantee against NSAID-related stomach irritation.)
I hope after reviewing this article you will get to know all the necessary information about the best pain relief cream. All the products that I mentioned above are the best selling and top rated. There is no reason to buy any one of the above items after reviewing each of the pain relief cream. However, if you have a severe health problem you should consult with your doctor.
The power of Luminas pain patches on pain and inflammation has successfully been measured with the help of thermography technology. When inflammation occurs, blood flow is increased in that area, causing the temperatures to rise. This is identifiable on our infrared cameras. Once a Luminas pain patch is applied to the area, you can see it working right away. In as little as 15 minutes, most of the inflammation and pain had disappeared.
Research shows that certain forms of magnesium can be effective for pain relief and muscle relaxation, as well as nerve pain. Many people in our society are magnesium deficient, so it may be a good idea to supplement. Magnesium glycinate is known to be a highly bioavailable form. Magnesium citrate can be used by those who tend toward constipation, as it has an additional effect of loosening the bowels.
If you find yourself snacking at night before bed, it may be because you're bored or anxious — not truly hungry — and eating makes you feel better. Try eating a healthy dinner a bit later in the evening. If your stomach is truly growling before bed, try a protein-based snack like a hard-boiled egg or a slice of cheese. A few spoonfuls of yogurt or some fruit is another good option. 
The first generic (cheaper) equivalent of Voltaren® Gel entered the marketplace in 2016, produced by Amneal Pharmaceutical. It should be widely available now. Both products are still prescription-only in the US, but fortunately they are over-the-counter almost everywhere else (there’s a rack of tubes of Voltaren by the till at my neighbhourhood drugstore).
You probably wonder what are in the topical products, right? Menthol is cooling, capsaicin from chili pepper makes your skin feel warm. Methyl salicylate, from the oil of wintergreen, also gives you a feeling of warmth or heat. Eucalyptus is also cooling. These ingredients are known as counter-irritants causing the nerves to have a less intense sensation where blood circulation might increase at the area as the theory goes. We just do not know the exact method for working.
This substance comes from edible hot peppers and helps to reduce a substance in the body that works to produce pain. Be careful with gels and creams that contain this substance, you must wash your hands after using, especially before touching sensitive areas of the body. Some people may also experience adverse reactions to this ingredient. When first using a gel or cream with capsaicin use just a small amount in a small area to see how you react to it.
Consumer Reports is an independent, non-profit organization dedicated to helping consumers. We make it easy to buy the right product from a variety of retailers. Clicking a retailer link will take you to that retailer’s website to shop. When you shop through retailer links on our site, we may earn an affiliate commission – 100% of the fees we collect are used to support our mission. Learn more. Our service is unbiased: retailers can’t influence placement. All prices are subject to change.

A 2008 study published in the journal Spine found "strong evidence that acupuncture can be a useful supplement to other forms of conventional therapy" for low back pain. After analyzing 23 clinical trials with a total of 6,359 patients, the study authors also found "moderate evidence that acupuncture is more effective than no treatment" in relief of back pain.


Green tea has long been recognized to have cardiovascular and cancer preventative characteristics due to its antioxidant properties. Its use in the treatment of arthritic disease as an anti-inflammatory agent has been recognized more recently. The constituents of green tea are polyphenolic compounds called catechins, and epigallocatechin-3 galate is the most abundant catechin in green tea.
Warming tissues eases arthritis pain by increasing blood flow to affected areas, which decreases inflammation, relaxes tight muscles, and eliminates waste products, like lactic acid, that cause stiffness and soreness. Cold decreases blood flow to reduce swelling, slows the transmission of pain signals through nerves, and inhibits inflammatory chemicals. Cold therapy is best for pain and swelling after exercise, during a flare, or in the first 48 to 72 hours after an injury. Here are some ways to soothe joint pain with heat and cold at home:
You are eligible for a full refund if no ShippingPass-eligible orders have been placed. You cannot receive a refund if you have placed a ShippingPass-eligible order. In this case, the Customer Care team will remove your account from auto-renewal to ensure you are not charged for an additional year and you can continue to use the subscription until the end of your subscription term.
Cinnamon is a popular natural remedy for helping to control blood sugar, but it can also keep inflammation levels low in the body and improve digestion. (20) Spices have long been used for medicinal purposes, but in a modern day where pharmaceutical options abound, it is rarer to use food as medicine. Still, cinnamon and other spices can have broad anti-inflammatory benefits and in many cases, can be equally as effective to (or more) than NSAIDs, whether over-the-counter or prescription. (21)
3. Menthol, Eucalyptus and Mint Oils. Pain relieving creams containing either one or a combination of menthol, camphor, eucalyptus, spearmint, wintergreen or peppermint are thought to work by "confusing" nerve signals into feeling heat and cold sensations instead of pain.  Popular brands include Mentholatum Deep Heating Rub® and Icy Hot® (which may contain methyl salicylate too).  While many pain sufferers say these products work, its' relief is temporary at best.  These pain relief creams have to be reapplied frequently and tend to have strong fragrances.
Rubbing the pain relief cream on the affected area reduces the pain quickly. When you rubbing the cream or gel on the affected area then it warms the spot and increases the blood flow. The bodily action of massaging or rubbing allows the active ingredients to absorb into the affected skin smoothly. So you feel relaxed from severe pain such as back pain or knee pain.

Release your inner endorphins. Endorphins are the natural pain relievers produced by your body. They work by binding to the opioid receptors in your brain to block the perception of pain, similar to opioid pain medications, such as oxycodone or morphine. Spurring increased production of these natural hormones can substantially help reduce your pain, as well as produce profound feelings of pleasure and satisfaction.1
Cognitive behavioral therapy can benefit your health and well being in numerous ways. It is a therapeutic technique that helps you to identify negative thoughts, emotions, and behaviors and learn how to replace them with productive alternatives. Cognitive behavioral therapy is an effective treatment for chronic pain,[15,16] as you learn to respond less to your pain and live a life less controlled by your pain.
×