The only side effect most of these products have is odor. Some of them were reviewed as being neutral to actually smelling good, while others were reported to have quite a strong smell you might not like. A lot of this has to do with the nature of the ingredients in pain relieving treatments. Mentholated ingredients give natural relief, but they do tend to have a strong odor that accompanies them.
5. Birch Leaf (Betula Lenta) – The leaves from the Birch tree act much like cortisone, a prescription drug used to treat endocrine disorders, arthritis, lupus, skin disease, autoimmune disorders, and more. A main chemical compound found in Birch leaves is methyl salicylate, similar to salicylic acid used in aspirin. It is anti-spasmodic, analgesic, astringent, antifungal, diuretic, detoxifying, reduces oxidative damage to skin (stopping wrinkles), and enhances circulation. It also promotes enzymatic secretions in the body. It is truly one of the first powerful pain-relievers ever used.
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Cold and heat therapies. It's best to use cold compresses or an ice pack, not heat, immediately following a back injury, since this can alleviate pain by numbing the area and prevent or reduce swelling. About 48 hours after the onset of back pain, though, applying heating pads or a hot-water bottle to your back may be helpful. The warmth soothes and relaxes aching muscles and increases blood flow, which helps the healing process. Keep in mind that heat therapy is only helpful for the first week.
The displayed muscle relief cream of Ultra Freeze house comprises an inventive formulary that unifies the inherent pain-killing trait of Menthol with other virtuous clinical elements and in effect renders a durable cooling action and optimum soothing sensation that fortifies at the depth of physiology with the passing of time. A brain-child of DR Pat, the ointment consumes about 10 minutes to work and while catering the peak level of healing retains the ‘Cool’ feel for half-an-hour. The muscle relief cream is preferred by pros for post work-out restore phase, treatment of Tennis and Golfer’s Elbow, and to meet all kinds of soreness, neck, ankle and buttock aches and shoulder immobility. It comes in a concentrated 160z density.

Turmeric can be consumed in a variety of forms, including as a spice added to foods or drinks and encapsulated for those who are not tolerant of the signature spicy taste. Two to three teaspoons of turmeric daily can help to provide therapeutic levels of relief and preventive benefits with little side effects. Note: Turmeric absorbs best when taken in combination with black pepper (approximately 1/4 teaspoon of black pepper for every 1 teaspoon of turmeric). (17)
Perform vends this distinguished muscle rub cream, which carves its own niche amongst counterparts, principally for the impeccable effectiveness over persistent type muscle and tendon pains. The Non-NSAID graded salve is recommended for after training physiology refurbishing endeavor and is an indispensable elect for treating both minor and severe tissue lesion issue. It is crafted by availing the innate analgesic feature of Menthol and is judiciously sans Paraben. The muscle rub cream is also operative over arthritis and muscle redness and comes in a 4oz volume gel tube. It scales to an extent 1.5 x 2 x 6.2 inches and is vended in two more patterns of Roll-On and Spray.
Can stomach problems cause lower back pain? The back is a sensitive part of the body, which has many nerves and organs nearby. This means that issues such as digestive conditions can occur at the same time as back pain. Back pain and bloating are common symptoms of injury, pregnancy, or gastrointestinal problems. Treatment depends on the cause. Learn more here. Read now
Nonsteroidal anti-inflammatory drugs (NSAIDs) have shown efficacy in patients with osteoarthritis (OA) pain but are also associated with a dose-dependent risk of gastrointestinal, cardiovascular, hematologic, hepatic, and renal adverse events (AEs). Topical NSAIDs were developed to provide analgesia similar to their oral counterparts with less systemic exposure and fewer serious AEs. Topical NSAIDs have long been available in Europe for the management of OA, and guidelines of the European League Against Rheumatism and the Osteoarthritis Research Society International specify that topical NSAIDs are preferred over oral NSAIDs for patients with knee or hand OA of mild-to-moderate severity, few affected joints, and/or a history of sensitivity to oral NSAIDs.
Relief goes beyond common sport and muscle creams to relieve your pain.  With the highest level mixture of menthol and methyl salicylate of sports creams and balms, Relief quickly starts working.  Just one application of our non-greasy, no mess applicator provides the temporary relief you have been looking for.  Simply rub the balm on directly from the container – no more messy hands.  We take time tested ingredients that work and deliver them in an easy to use applicator to alleviate your muscle and joint pain.  Pick up some Relief and don’t let pain stop you.
People who used an ointment that contains this plant-based extract for 5 days reduced the intensity of lower back pain by 95%, according to a 2009 study conducted by Merck (which manufactures the ointment). In comparison, a placebo group had a 38% reduction in pain during that same time, according to the study in the British Journal of Sports Medicine. Look for comfrey root ointment in health food stores or online. Just don't use it for more than 10 days at a time—it can be toxic.
Improve your posture. Good posture can prevent future arthritis pain. Years of compensating for a sore knee can result in pain in a hip or ankle. Jutting the abdomen forward can cause lower back pain, as can slouching in a desk chair. Consult a physical therapist. A physical therapist can observe how you sit, stand and walk and teach you how to adjust your posture so you can move with less pain.
Rosenzweig, S., Greeson, J. M., Reibel, D. K., Green, J. S., Jasser, S. A., & Beasley, D. (2010, January). Mindfulness-based stress reduction for chronic pain conditions: Variation in treatment outcomes and role of home meditation practice. Journal of Psychosomatic Research, 68(1), 29–36. Retrieved from https://www.sciencedirect.com/science/article/pii/S0022399909000944

From tissue spasms to neurological aches and from shooting aches to twist, this best muscle rub cream of Living Well Nutraceuticals is lab-accredited to heal all patterns of pain. Its exquisiteness is essentially fortified by the presence of Cetyl Myristoleate or CMO that enacts in depth over swelled up muscles, tendons and joints and eradicates the very inflammation—the root cause of all pains. The best muscle rub cream also owns Methylsulfonylmethane or MSM, which again reaches into the body cells and opens those up to prevent the aches affecting physique. The ointment is moreover nurtured with cruxes of Belladonna and Rhus Tox and caters enduring soothe. It comes in a 3oz density tube.


Relief is the more natural alternative when compared with non-steroidal anti-inflammatory drugs (NSAIDs), all of which note they may cause stomach or intestinal problems, such as bleeding and ulcers, and may increase the chance of heart attacks and strokes. Relief is a totally vegan product that contains no animal or animal derived ingredients, and has never been tested on animals.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: acetaminophen (Tylenol, in other products); angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (Prinivil, Zestril, in Prinzide and Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers such as candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); certain antibiotics, beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, Innopran); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); lithium (Lithobid); medications for seizures, and methotrexate (Otrexup, Rasuvo, Trexall). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
Low and lower back pain can vary from dull pain that develops gradually to sudden, sharp or persistent pain felt below the waist. Unfortunately, almost everyone, at some point during life will experience low back pain that may travel downward into the buttocks and sometimes into one or both lower extremities. The most common cause is muscle strain often related to heavy physical labor, lifting or forceful movement, bending or twisting into awkward positions, or standing in one position too long.
“I would rate Corganics Relief pain cream as EXCELLENT! I have a diagnosis of Stage 4 lung cancer with metastases to bones, spine, brain and liver. Every morning and night I use it on my lower back and pelvis, calves and shins. I rely on the relief I get from Relief pain cream to be comfortable all day. Thank you for giving me the peace of mind with such a quality product. I appreciate your excellence!” *

Keep all appointments with your doctor and the laboratory. Your doctor will monitor your symptoms carefully and will probably take your blood pressure and order certain tests to check your body's response to topical diclofenac (Pennsaid, Voltaren). Be sure to tell your doctor how you are feeling so that the doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.


Chill it. Ice is best in the first 24 to 48 hours after an injury because it reduces inflammation, says E. Anne Reicherter, PhD, PT, DPT, associate professor of Physical Therapy at the University of Maryland School of Medicine. "Even though the warmth feels good because it helps cover up the pain and it does help relax the muscles, the heat actually inflames the inflammatory processes," she says. After 48 hours, you can switch to heat if you prefer. Whether you use heat or ice -- take it off after about 20 minutes to give your skin a rest. If pain persists, talk with a doctor.
The NF-kB molecule is a transcription factor that controls the transcription of DNA for the perpetuation of the inflammatory immune response. It acts as a switch to turn inflammation on and off in the body. NF-kB has the ability to detect noxious stimuli, such as infectious agents, free radicals, and other cellular injuries, and then directs DNA to produce inflammatory cytokines. The NF-kB proteins are localized in the cytoplasm of the cell and are associated with a family of inhibitory proteins known as inhibitor of kB (IkB).[43,119] The TNF-α, and especially IL-1b, can also directly stimulate enzymes known as matrix metalloproteinases, which break down extracellular collagen matrix, a hallmark of inflammatory joint disease.[32,76,77] The IkB proteins are normally bound to NF-kB and block their nuclear localization signal. A variety of provoking stimuli can degrade the IkB and result in the nuclear translocation of NF-kB to be free to activate DNA synthesis of inflammatory cytokines [Figure 2].

Omega-3 EFA, found in fish oil, can directly reduce the degenerative enzymes, aggrecanase and matrix metalloproteinase, as well as IL-1, TNF-α, and COX-2, to reduce the inflammation in synovial cartilage. A recent study of 250 patients with cervical and lumbar disc disease, who were taking NSAIDs, revealed that 59% could substitute fish oil supplements as a natural anti-inflammatory agent for the NSAIDs.[71] The recommended dosage is a total of 1.5–5g of EPA and DHA per day, taken with meals.
Amanda has a Masters of Science in Nutrition from Syracuse University which equipped her with courses applied to licensure as a dietitian. She also worked as a Program Director for the Wellness and Fitness Department for the YMCA. She is well versed in physical fitness, with a certificate from the National Academy of Sports Medicine in physical fitness training. She has taught numerous fitness classes, including college courses in the Athletic Department, as an adjunct instructor, at the SUNY University at Buffalo. She currently resides with her husband in the NYC area, and loves to put her knowledge of anatomy and physiology to use by being active. Both her and her husband are self-declared "foodies."
The evaluation of nutraceutical preparations with appropriately designed controlled studies has exploded in recent years. There is now a greater degree of confidence based on controlled study design and improved quality of the investigators that has strengthened positive findings found using natural compounds to treat diseases. It is important for healthcare practitioners to learn about these scientific studies to counsel patients who are taking various dietary supplements, herbs minerals and vitamins for both disease treatment and prevention.

Topical gels have been shown to reduce the need for oral analgesics which is a good thing for reducing side effects.One trial found that topical capsaicin reduce pain more than placebo in people with AS, although it can cause burning sensations. Another trial used a gel form of a drug called tenoxicam (an NSAID) that suggested it might be helpful. Do ask your specialist if you can try something like voltarol – or a stronger version on prescription – and follow their individual advice. They may prefer you to have some oral anti-inflammatory on board to reduce inflammation throughout the body, however.


Many individuals perceive surgery as the best modality for their health issues and sometimes it is.  However, research has indicated that nerve damage unavoidably produced during a surgical operation will cause chronic pain in 15 – 50% of patients (3).  Other individuals are severely damaged by treatments such as chemotherapy and radiation that cause states of increased inflammation and pain.
Glutathione is a natural protein found within every cell in the body and consists of the amino acids Glutamic acid, L-cysteine, L-glycine. It is produced by the liver and is also found in fruit, vegetables and meats like mutton, lamb and beef. It is the most powerful antioxidant in the body and helps protect cells from free radical damage and oxidative stress, thereby improving cellular health and strengthening the immune system. As such, in addition to a host of other diseases, L-glutathione is useful in the natural treatment of rheumatoid arthritis.
This substance comes from edible hot peppers and helps to reduce a substance in the body that works to produce pain. Be careful with gels and creams that contain this substance, you must wash your hands after using, especially before touching sensitive areas of the body. Some people may also experience adverse reactions to this ingredient. When first using a gel or cream with capsaicin use just a small amount in a small area to see how you react to it.
Open the cream and gently use it on the affected area of your body, you will feel a tingling sensation which means it works. The best part is that the Pain Relief Cream gets quickly absorbed through your skin and leaves no traces of greasiness or stickiness. Another vital thing you need to know is that such creams nowadays. You just open the cream and apply it to the affected area of your body. There is also best pain relief spray out on the market which also helps you to feel tingling sensation and relief you from pain.
Prolotherapy treatments work by naturally promoting a minor inflammatory response near damaged connective tissue, promoting regeneration and the growth of new, healthier tissue in the process. These treatments have been used to effectively reduce or heal chronic musculoskeletal conditions of the back, such as herniated/bulging discs, arthritis, osteoarthritis or other chronic joint pains, and tendonitis that affects the lower body and causes compensations in the spine. (7) For the most benefits, it seems that prolotherapy works best when combined with other back pain treatments, such as spinal manipulation, exercise and in some cases medications when needed.
Most of these gels and creams won’t cure your ailment. You’ll probably run into countless negative reviews of products from people that complain that their pain is not gone. These types of products are not a cure. Pain relief creams and gels are a helpful way to reduce pain. With acute pain, these gels and creams help users get relief until treatment can occur. In the case of a sprained ankle or torn muscle, for instance, using this kind of medicine can be a good alternative to NSAIDs to help reduce pain. For chronic ailments like arthritis, these substances are merely a way to help sufferers cope with pain. They are a band-aid. Some aches and pains may be helped with further treatment but don’t expect miracles with these types of products. Just because they don’t completely remove pain doesn’t mean they aren’t helpful in some instances and for some people.
For short-term pain relief, over-the-counter pain relievers including acetaminophen and NSAIDs (non-steroidal anti-inflammatory drugs) are sometimes suggested. The most common NSAIDs include aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve). Potential side effects of NSAIDs include stomach and liver problems. Talk to your doctor if you don't find relief after taking the recommended dose.

We looked at both gels and creams to create our top ten list. How did we evaluate consistency? We looked at whether the substances stained, went on greasy, or were otherwise messy to deal with. Did users like the feel of the gel or cream on their skin? Why or why not? We also looked at whether formulas were quick drying and whether they left a residue. When it came to ingredients, we wanted to select as many options as possible with natural ingredients that were easily recognizable.


“I finally found relief. I've got fibromyalgia and I'm always in pain. I tried Relief because it says, "Chiropractor recommended," so what did I have to lose. This was the BEST chance I ever took!! I'm so happy I ordered this. I will be a customer for life as long as it works. I'm sold. I've got nothing but GREAT things to say about this cream. It does exactly what it's called, it gives you relief. Thank you SO MUCH :)" *
The most commonly used drugs to treat chronic pain conditions include opioids (morphine), nonsteroids (salicylates such as aspirin and ibuprofen), antidepressants, antiepileptics and anti-nerve growth factor inhibitors.   All of these drugs have awful side effects and addictive tendencies.  In fact, prescription and over the counter pain medications are the fastest growing drug addiction in North America (1).
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